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Clareo Health | Brain Cancer Clinical Trials in Cleveland | 102 Studies

Clinical Trials Brain CancerCleveland

Brain Cancer Clinical Trials in Cleveland

Find 102 clinical trials for brain cancer near Cleveland, Ohio. Connect with research centers in your area.

All Brain Cancer trials nationwide All trials in Cleveland

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Status

RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4Not applicable

Who can join

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Showing 1-20 of 102 trials

CompletedA Study Assessing Pamiparib With Radiation and/or Temozolomide (TMZ) in Participants With Newly Diagnosed or Recurrent GlioblastomaThe primary objective of this study is to evaluate the safety, efficacy and clinical activity of Pamiparib in combination with radiation therapy (RT) and/or temozolomide (TMZ) in…NCT03150862·Tucson, Arizona and 21 others TerminatedCelecoxib in Patients With Newly Diagnosed GBM Who Are Receiving Anticonvulsant Drugs and Undergoing RTRATIONALE: Celecoxib may stop the growth of tumor cells by blocking the enzymes necessary for their growth.NCT00068770·Tampa, Florida and 6 others

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Data from ClinicalTrials.govTerms

CompletedA Study of a Retroviral Replicating Vector Combined With a Prodrug Administered to Patients With Recurrent Malignant GliomaThis is a multicenter, open-label, ascending-dose trial of the safety and tolerability of increasing doses of Toca 511, a Retroviral Replicating Vector (RRV), administered to…NCT01156584·Duarte, California and 9 others

CompletedSafety & Radiation Distribution Study of Cotara® in Patients With Recurrent Glioblastoma MultiformeRATIONALE: Cotara® is an experimental new treatment that links a radioactive isotope (iodine 131) to a targeted monoclonal antibody.NCT00509301·Phoenix, Arizona and 3 others

CompletedPhenylacetate in Treating Children With Recurrent or Progressive Brain TumorsRATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.NCT00003241·Los Angeles, California and 5 others

Active not recruitingVorinostat and Temozolomide in Treating Patients With Malignant GliomasThis phase I trial is studying the side effects and best dose of vorinostat when given together with temozolomide in treating patients with malignant gliomas.NCT00268385·Birmingham, Alabama and 16 others

CompletedCombination Adenovirus + Pembrolizumab to Trigger Immune Virus EffectsGlioblastoma (GBM) and gliosarcoma (GS) are the most common and aggressive forms of malignant brain tumor in adults and can be resistant to conventional therapies.NCT02798406·Little Rock, Arkansas and 14 others

CompletedDovitinib in Treating Patients With Recurrent or Progressive GlioblastomaThis phase II trial studies how well dovitinib works in treating patients with recurrent or progressive glioblastoma.NCT01753713·Cleveland, Ohio

CompletedChemotherapy in Treating Patients With Progressive or Recurrent Brain TumorsRATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.NCT00012038·Birmingham, Alabama and 9 others

CompletedSurgery Followed by Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma MultiformeRATIONALE: Internal radiation uses radioactive material placed directly into or near a tumor to kill tumor cells.NCT00053183·Birmingham, Alabama and 9 others

CompletedRadiation Therapy and Tamoxifen in Treating Adults With Newly Diagnosed Supratentorial Glioblastoma MultiformeRATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. Drugs such as tamoxifen may make the tumor cells more sensitive to radiation therapy.NCT00006388·Birmingham, Alabama and 256 others

CompletedTemozolomide Plus Lomustine Followed by Radiation Therapy in Treating Patients With High-Grade Malignant GliomaRATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.NCT00006024·Birmingham, Alabama and 234 others

CompletedImaging Procedure Using ALA in Finding Residual Tumor in Grade IV Malignant AstrocytomaRATIONALE: Imaging procedures that use aminolevulinic acid (ALA) may help find and diagnose residual tumor in participants with grade IV malignant astrocytoma who are undergoing…NCT00752323·Cleveland, Ohio

Active not recruitingA Phase 1b / 2 Drug Resistant Immunotherapy With Activated, Gene Modified Allogeneic or Autologous γδ T Cells (DeltEx) in Combination With Maintenance Temozolomide in Subjects With Recurrent or Newly Diagnosed GlioblastomaThis multicenter, Phase 1b/2 study is being conducted to determine if the experimental cell therapy is safe, tolerable and can delay the return of cancer in patients with a newly…NCT05664243·Birmingham, Alabama and 4 others

RecruitingTesting the Addition of an Anti-cancer Drug, Selinexor, to the Usual Chemotherapy Treatment (Temozolomide) for Brain Tumors That Have Returned After Previous TreatmentThis phase I/II trial tests the safety, side effects and best dose of selinexor given in combination with the usual chemotherapy (temozolomide) and compares the effect of this…NCT05432804·Phoenix, Arizona and 38 others

RecruitingLiving Well With Brain Cancer: A Group-Based Intervention to Promote Whole-Person Well-BeingThe goal of this clinical trial is to learn if the newly designed group self-management program is feasible to conduct and improves mental and behavioral health outcomes compared…NCT07628647·Aurora, Colorado and 1 other

CompletedStudy of a Retroviral Replicating Vector Given Intravenously to Patients Undergoing Surgery for Recurrent Brain TumorThis is a multicenter study evaluating the safety and tolerability of Toca 511 administered intravenously to patients with recurrent or progressive Grade III or Grade IV Gliomas…NCT01985256·Irvine, California and 5 others

TerminatedAminolevulinic Acid in Visualizing a Tumor During Surgery in Patients With Glioblastoma MultiformeThe purpose of this study is to investigate the safety and performance of an investigational agent, known as 5-ALA or Gliolan (aminolevulinic acid), that many be useful to a…NCT01575275·Cleveland, Ohio

CompletedA Study of DSP-7888 Dosing Emulsion in Combination With Bevacizumab in Patients With Recurrent or Progressive Glioblastoma Following Initial TherapyThis is an event driven, adaptive design, a randomized, active-controlled, multicenter, open-label, parallel groups, Phase 3 study of DSP-7888 Dosing Emulsion plus Bevacizumab…NCT03149003·Birmingham, Alabama and 60 others

RecruitingStudy of Silevertinib With Temozolomide for the Treatment of Newly Diagnosed GBM With Unmethylated MGMT and EGFRvIIIThe purpose of this study is to see if combining silevertinib with temozolomide after surgery and radiotherapy helps treat newly diagnosed glioblastoma (GBM) better than using…NCT07326566·Birmingham, Alabama and 37 others

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