Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Forest Laboratories
Age
18–85
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Eligible for study treatment within 3-9 hours after onset of stroke symptoms.
Score of 4-24 on the NIHSS with clinical signs of hemispheric infarction (i.e. hemiparesis) suggestive of ischemic stroke.
Distinct penumbra (at least 20%), measured by MRI (PWI/DWI) or perfusion CT, related to middle cerebral artery (MCA), anterior cerebral artery (ACA), or posterior cerebral artery (PCA) territory in a hemispheric distribution.
You may not be if
History or clinical presentation of intracranial hemorrhage (ICH), subarachnoid hemorrhage, arteriovenous malformation, aneurysm, or cerebral neoplasm.
Rapidly improving neurological symptoms.
Pre-stroke MRS score of \> 1 (including previous disability).
Suspected acute vertebral or basilar artery occlusion.
Current use of anticoagulants and a prolonged prothrombin time.
Uncontrolled hypertension.
Baseline hematocrit of \< 0.25.
Baseline platelet count \< 100,000/mm3.
Clareo Health | Study of Desmoteplase (International Nonproprietary Name [INN]) in Acute Ischemic Stroke (DIAS-2)