Clinical Trials in Boston

Showing 1961-1980 of 17,836 trials

Starlight Cardiovascular Lifeline Ductus Arteriosus Stent IDE Study

NCT07114718

Starlight Cardiovascular, Inc. is sponsoring a prospective, multi-center, study to evaluate safety and effectiveness of the Lifeline Ductus Arteriosus Stent System. The study device is a stent that is designed to maintain patency of the Ductus Arteriosus for children who need blood flow through that part of the heart.

Congenital Heart DiseaseCongenital Heart Disease (CHD)

Starlight Cardiovascular Inc35 participantsStarted Dec 2025

Los Angeles, California, United States • Stanford, California, United States • Aurora, Colorado, United States +4 more locations

COMPLETEDPhase 3< 1 mile

Cisplatin With or Without Monoclonal Antibody Therapy in Treating Patients With Metastatic or Recurrent Head and Neck Cancer

NCT00003809

RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Monoclonal antibodies can locate cancer cells and either kill them or deliver tumor-killing substances to them without harming normal cells. It is not yet known whether cisplatin plus monoclonal antibody therapy is more effective than cisplatin alone for metastatic or recurrent head and neck cancer. PURPOSE: Randomized double-blinded phase III trial to compare the effectiveness of cisplatin with or without monoclonal antibody in treating patients who have metastatic or recurrent head and neck cancer.

Head and Neck Cancer

Eastern Cooperative Oncology GroupStarted Aug 1999

Scottsdale, Arizona, United States • Scottsdale, Arizona, United States • Los Angeles, California, United States +73 more locations

Starlight Cardiovascular Lifeline Ductus Arteriosus Stent IDE Study

Cisplatin With or Without Monoclonal Antibody Therapy in Treating Patients With Metastatic or Recurrent Head and Neck Cancer

Find Trials by Condition in Boston

Expanded Access Program for OOS Obe-cel

Plasma and Radiologic Biomarkers of Response to ECP in Lung Transplant Recipients With CLAD

Fremanezumab, Migraine and Sleep

GCC19CART for Patients With Metastatic Colorectal Cancer

REFOCUS: A First-in-Human Study of Highly Selective FGFR2 Inhibitor, RLY-4008, in Patients With ICC and Other Advanced Solid Tumors

Testing the Addition of 131I-MIBG or Lorlatinib to Intensive Therapy in People With High-Risk Neuroblastoma (NBL)

Mobile Health and Social Media Physical Activity Intervention Among Adolescent and Young Adult Childhood Cancer Survivors, the StepByStep Study

Behavioral Activation for Independence in Older Veterans

A Study to Assess the Efficacy and Safety of Satralizumab in Duchenne Muscular Dystrophy (DMD)

An Induction Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Ulcerative Colitis

Study Comparing Combination of LGX818 Plus MEK162 Versus Vemurafenib and LGX818 Monotherapy in BRAF Mutant Melanoma

A Trial of Etelcalcetide in Pediatric Participants With Secondary Hyperparathyroidism and Chronic Kidney Disease on Hemodialysis

Open-Label Extension of EryDex Study IEDAT-04-2022

A Study to Test Inavolisib Treatments in Participants With Early-Stage, PIK3CA-Mutated Breast Cancer

A Phase Ⅲ Clinical Study of HLX22 in Combination With Trastuzumab and Chemotherapy for the Treatment of Gastroesophageal Junction and Gastric Cancer

Defining Clinical Endpoints in Limb Girdle Muscular Dystrophy (LGMD)

A Study to Assess the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, Immunogenicity and Anti-tumour Activity of IPN01203 in Adults With Locally Advanced or Metastatic Solid Tumours Exposed to Immune Checkpoint Inhibitor Therapies

SMP-3124LP in Adults With Advanced Solid Tumors