A Study to Evaluate ASP0367 in Participants With Reduced Maximum Oxygen Uptake Due to Poor Systemic Oxygen Extraction

The study will consist of a screening period (up to 27 days \[approximately 4 weeks\]), treatment period (up to 44 days \[6 weeks\]) and follow-up period (7 days \[1 week\]). The study will be completed with an end-of-study visit (ESV). The ESV will take place 7 days (1 week) after the end-of-treatment on day 44 (week 6) or 7 days (1 week) after early discontinuation from the study. The anticipated total duration of the study for each participant, including screening and follow-up, is approximately 75 days (11 week). An interim analysis may be performed before the end of the study.