Clinical Trials in Boston

Showing 1621-1640 of 17,836 trials

Autus Valve Continued Access Study (CAS)

NCT07466745

Prospective, single-arm, multi-center, continued access study of the Autus Size-Adjustable Valve in pediatric patients aged 18 months to 16 years requiring surgical pulmonary valve replacement. The Autus Valve may be expanded pre-implant to match the subject's body size. Subjects will be evaluated prior to the Autus Valve implant procedure, immediately post-implantation, at hospital discharge, 30 days, 6 months, and annually through 10 years. The Autus Valve may be expanded post-implant via transcatheter balloon dilation to accommodate growth of the subject.

Congenital Heart Disease

Autus Valve Technologies, Inc.36 participantsStarted Apr 2026

Los Angeles, California, United States • Aurora, Colorado, United States • Atlanta, Georgia, United States +7 more locations

Active Not RecruitingPhase 2< 1 mile

Study of Efficacy and Safety of LXH254 Combinations in Patients With Previously Treated Unresectable or Metastatic Melanoma

NCT04417621

The primary purpose of this study is to evaluate the efficacy of LXH254 combinations in previously treated unresectable or metastatic melanoma

Melanoma

Novartis Pharmaceuticals134 participantsStarted Oct 2020

Los Angeles, California, United States • San Francisco, California, United States • Fort Myers, Florida, United States +33 more locations

Autus Valve Continued Access Study (CAS)

Study of Efficacy and Safety of LXH254 Combinations in Patients With Previously Treated Unresectable or Metastatic Melanoma

Find Trials by Condition in Boston

A Study With NKT5097 for Adults With Advanced/Metastatic Solid Tumors

CAR- PRISM (PRecision Intervention Smoldering Myeloma)

A Clinical Study to Test if an Investigational Treatment Called BNT326 is Safe and Potentially Beneficial When Used Alone or in Combination With Other Investigational Treatments Such as BNT327, for People With Advanced Malignant Tumors

A Study of Zilovertamab Vedotin (MK-2140) as Monotherapy and in Combination in Participants With Aggressive and Indolent B-cell Malignancies (MK-2140-006)

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

Improving the Quality of Care for Asthma Patients at Risk of Exacerbations

Atrial Fibrillation Risk Estimation With Single-lead Handheld Electrocardiograms

Healthy And Positive Pathways for Young People With Type 1 Diabetes (HAPPY T1D)

Investigation of Anatomical Correlates of Speech Discrimination

A Study of Dotinurad Versus Allopurinol in Participants With Gout

A Study Comparing KB803 and Matched Placebo in Patients With Dystrophic Epidermolysis Bullosa

Phase 3 Study of ALXN1850 in Pediatric Participants With HPP Previously Treated With Asfotase Alfa

A Study to Test Whether Survodutide (BI 456906) Helps People Living With Overweight or Obesity Who do Not Have Diabetes to Lose Weight

A Study of an Intermittent ADT Approach With Apalutamide Monotherapy in Participants With mCSPC

Study of BG-T187 Alone and in Combination With Other Therapeutic Agents in Participants With Advanced Solid Tumors

A Long-term Safety and Efficacy Study Evaluating APG777 in Atopic Dermatitis

Lp(a) Lowering Study of Pelacarsen (TQJ230) With Background Inclisiran in Participants With Elevated Lp(a) and Established ASCVD

Study Evaluating the Efficacy and Safety of Povorcitinib in Adults With Chronic Spontaneous Urticaria