Clinical Trials in Boston

Showing 1641-1660 of 17,836 trials

Autus Valve Continued Access Study (CAS)

NCT07466745

Prospective, single-arm, multi-center, continued access study of the Autus Size-Adjustable Valve in pediatric patients aged 18 months to 16 years requiring surgical pulmonary valve replacement. The Autus Valve may be expanded pre-implant to match the subject's body size. Subjects will be evaluated prior to the Autus Valve implant procedure, immediately post-implantation, at hospital discharge, 30 days, 6 months, and annually through 10 years. The Autus Valve may be expanded post-implant via transcatheter balloon dilation to accommodate growth of the subject.

Congenital Heart Disease

Autus Valve Technologies, Inc.36 participantsStarted Apr 2026

Los Angeles, California, United States • Aurora, Colorado, United States • Atlanta, Georgia, United States +7 more locations

COMPLETEDNA< 1 mile

Healthy And Positive Pathways for Young People With Type 1 Diabetes (HAPPY T1D)

NCT05413239

In this 2-year randomized clinical trial, we will implement and assess the impact of a behavioral/psychoeducational intervention to reduce diabetes distress and improve glycemic outcomes in adolescents and young adults, aged 14-25 years, with T1D in order to optimize their short-term and long-term health.

Type 1 Diabetes

Joslin Diabetes Center217 participantsStarted Jul 2022

Palo Alto, California, United States • Boston, Massachusetts, United States

Autus Valve Continued Access Study (CAS)

Healthy And Positive Pathways for Young People With Type 1 Diabetes (HAPPY T1D)

Find Trials by Condition in Boston

A Clinical Study to Test if an Investigational Treatment Called BNT326 is Safe and Potentially Beneficial When Used Alone or in Combination With Other Investigational Treatments Such as BNT327, for People With Advanced Malignant Tumors

Atrial Fibrillation Risk Estimation With Single-lead Handheld Electrocardiograms

A Long-term Extension Study of PCI-32765 (Ibrutinib)

A Pilot Study to Assess Effects of Self-Administered Nitrous Oxide (SANO) on Urodynamic Study (UDS) Parameters

A Study of Zilovertamab Vedotin (MK-2140) as Monotherapy and in Combination in Participants With Aggressive and Indolent B-cell Malignancies (MK-2140-006)

CAR- PRISM (PRecision Intervention Smoldering Myeloma)

A Study to Evaluate XEN1101 as Adjunctive Therapy in Primary Generalized Tonic-Clonic Seizures

Genetic and Neural Predictors of Adolescent Depression

A Study of Dotinurad Versus Allopurinol in Participants With Gout

Clinical Trial to Evaluate the Safety and Effectiveness of Using the Tendyne Transcatheter Mitral Valve System for the Treatment of Symptomatic Mitral Regurgitation

Evaluate Efficacy and Safety of POS to Improve Distance-corrected Near Visual in Participants With Presbyopia

Study to Assess the Adverse Events of Oral ABBV-932 in Adult Participants With Depressive Episodes Associated With Bipolar I or II Disorder

An Open-label Study to Assess Safety and Efficacy of SZC in Paediatric Patients With Hyperkalaemia

A Study of an Intermittent ADT Approach With Apalutamide Monotherapy in Participants With mCSPC

A Study to Assess the Efficacy and Safety of Afimkibart (RO7790121) in Participants With Moderate to Severe Atopic Dermatitis

Study of BG-T187 Alone and in Combination With Other Therapeutic Agents in Participants With Advanced Solid Tumors

A Long-term Safety and Efficacy Study Evaluating APG777 in Atopic Dermatitis

A Study of Teclistamab in Participants With Relapsed or Refractory Multiple Myeloma