Clinical Trials in Boston

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Cediranib Maleate in Treating Patients With Recurrent or Newly Diagnosed Metastatic Head and Neck Cancer

NCT00458978

This phase II trial is studying how well cediranib maleate works in treating patients with recurrent or newly diagnosed metastatic head and neck cancer. Cediranib maleate may stop the growth of head and neck cancer by blocking some of the enzymes needed for cell growth and by blocking blood flow to the tumor.

Recurrent Hypopharyngeal Squamous Cell CarcinomaRecurrent Laryngeal Squamous Cell CarcinomaRecurrent Laryngeal Verrucous Carcinoma+20 more

National Cancer Institute (NCI)6 participantsStarted Feb 2007

Boston, Massachusetts, United States

COMPLETEDPhase 1/2< 1 mile

A Phase 1-2 Study of PRT-201 Administered in Chronic Kidney Disease (CKD) Patients

NCT00679991

PRT-201 is a protein that causes long lasting dilation of blood vessels when applied to the outside surface of the blood vessel. The purpose of this study is to determine if PRT-201, when applied to a limited segment of blood vessel immediately after surgery to create an arteriovenous fistula (AVF), is safe, dilates the blood vessel, and increases blood flow through the AVF.

Chronic Kidney Disease

Proteon Therapeutics66 participantsStarted Nov 2008

Indianapolis, Indiana, United States • Iowa City, Iowa, United States • Portland, Maine, United States +8 more locations

Cediranib Maleate in Treating Patients With Recurrent or Newly Diagnosed Metastatic Head and Neck Cancer

A Phase 1-2 Study of PRT-201 Administered in Chronic Kidney Disease (CKD) Patients

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Increasing Evidence-based Clinical Practices in VA

Predicting Treatment Response to Stimulants in Adult ADHD Using Functional Magnetic Resonance Imaging

Interdisciplinary Study of Two Novel Anticonvulsants in Alcoholism

CSP #512 - Options in Management With Anti-Retrovirals

Ketoconazole, Hydrocortisone and Dutasteride in Asymptomatic Hormone Refractory Prostate Cancer

The Surgical Benefit and Pt.Tolerability Between Two Different Bowel Cleansing Regimens Performed Prior to Pelvic Reconstructive Surgery. Does One Bowel Cleansing Regimen Improve the Surgeons Visual Field Significantly Better Than the Other.

The Effects on Growth and Tolerance of a Routine Infant Formula Fed to Term Infants

Study of Technology-assisted Treatment of Adolescent Depression

Implementation, Fidelity, and Outcomes Following Novel and Usual Critical Time Intervention Training

A Study of Fluzone® High-Dose Vaccine Compared With Fluzone® Vaccine In Elderly Adults

Soft Tissue Ultrasound of Infections

A Study of LY2189265 Compared to Sitagliptin in Participants With Type 2 Diabetes Mellitus on Metformin

An Open-Label, Multi-Center Clinical Trial of Eculizumab in Pediatric Patients With Atypical Hemolytic-Uremic Syndrome

A Study of Retreatment With MabThera (Rituximab) in Combination With Methotrexate in Patients With Rheumatoid Arthritis (RA)

Safety of Exenatide Once Weekly in Patients With Type 2 Diabetes Mellitus Treated With Thiazolidinedione Alone or Thiazolidinedione in Combination With Metformin

Safety and Efficacy Study of Metaglidasen in Type 2 Diabetes in Patients Suboptimally Controlled on Insulin

Study to Evaluate the Efficacy of Rotigotine on Parkinson's Disease-Associated Pain

Comparison of Indacaterol 150 mcg Once Daily (o.d.) With Salmeterol/Fluticasone Propionate 50 mcg/500 mcg Twice Daily (b.i.d.)