Predicting Treatment Response to Stimulants in Adult ADHD Using Functional Magnetic Resonance Imaging

Exclusion Criteria

• •A history of non-response or intolerance to stimulants at adequate doses as determined by the clinician
• •Pregnant or nursing females
• •Serious, unstable medical illnesses including hepatic, renal, gastroenterological, respiratory, cardiovascular, endocrinologic (thyroid), neurologic (seizure), immunologic, or hematologic disease
• •Glaucoma
• •Clinically unstable psychiatric conditions including suicidality, homocidality, bipolar disorder, psychosis, or lifetime history of a clinically serious condition potentially exacerbated by a stimulant, such as mania or psychosis
• •Tics or diagnosis of Tourette's syndrome
• •Current (within 3 months) DSM-IV criteria for abuse or dependence with any psychoactive substance other than nicotine
• •Current use of psychotropic medications
• •Current use of MAO Inhibitor or use within the past two weeks
• •Claustrophobia or an standard contraindications to MRI scanning (metal in body)
• •Investigator and his/her immediate family; defined as the investigator's spouse, parent, child, grandparent or grandchild