Clinical Trials in Boston

Showing 1141-1160 of 8,503 trials

A 90 Day Observational Study as an Extension to the Phase 3,Open Labeled Exploratory Study of RELiZORB

NCT05635747

Children with inadequate intestinal absorption due to loss of large amounts of small bowel require intravenous nutrition (feeding through the vein) to sustain hydration and nutrition to avoid starvation and dehydration; however, intravenous (IV) nutrition can lead to complications including liver failure. Tube feeding directly to the small intestine avoids the complications of IV nutrition, but fats are not fully digestible due to inadequate bowel function. We propose to predigest the fat using a small cartridge attached to the feeding tube to allow for rapid absorption with the possibility of reducing or eliminating the need for intravenous nutrition. Goal of the observational study is to determine safety and tolerability of Relizorb Enzyme Cartridge for an additional 90 days after the original trial

Short Bowel SyndromeMalabsorption

Boston Children's Hospital32 participantsStarted Sep 2022

Boston, Massachusetts, United States

Active Not RecruitingPhase 2< 1 mile

Wide Excision Alone as Treatment for Ductal Carcinoma in Situ of The Breast

NCT00165256

The purpose of this study is to determine if wide excision (surgical removal) alone is adequate treatment for small, grade 1 or 2 ductal carcinoma in situ (DCIS) of the breast.

Ductal Carcinoma in Situ of the Breast

Dana-Farber Cancer Institute158 participantsStarted May 1995

Boston, Massachusetts, United States • Boston, Massachusetts, United States

COMPLETEDPhase 2< 1 mile

Acute Video-oculography for Vertigo in Emergency Rooms for Rapid Triage (AVERT)

NCT02483429

AVERT is a randomized controlled trial comparing video-oculography (VOG)-guided care to standard care to assess accuracy of diagnoses and initial management decisions for emergency department (ED) patients with a chief symptom of vertigo or dizziness suspected to be of vestibular cause. The trial will test the hypothesis that VOG-guided rapid triage (VRT) will accurately, safely, and efficiently differentiate peripheral from central vestibular disorders in ED patients presenting acute vertigo or dizziness, and that doing so has the potential to improve post-treatment clinical outcomes for these patients.

VertigoDizziness

Johns Hopkins University130 participantsStarted Dec 2017

Peoria, Illinois, United States • Baltimore, Maryland, United States • Boston, Massachusetts, United States +2 more locations

A 90 Day Observational Study as an Extension to the Phase 3,Open Labeled Exploratory Study of RELiZORB

Wide Excision Alone as Treatment for Ductal Carcinoma in Situ of The Breast

Acute Video-oculography for Vertigo in Emergency Rooms for Rapid Triage (AVERT)

Find Trials by Condition in Boston

Prevention of Colorectal Cancer Through Multiomics Blood Testing

Pilot Study Evaluating the Impact of Stress Reduction on Atherosclerotic : Heart and Mind Study

Impact of Transcutaneous Vagal Nerve Stimulation on Stress Response in Major Depression

Testing the Drug Atezolizumab or Placebo With Usual Therapy in First-Line HER2-Positive Metastatic Breast Cancer

Bioavailability of Ration Items Containing Tart Cherry Extract

The Effects of Cold Adaptation on Skin Blood Flow, Hand Function, and Comfort in Healthy Adults

Training for Urinary Leakage Improvement After Pregnancy

BrUOG 397: NEO Rad (LOW): Neoadjuvant Low Dose Stereotactic Body Radiotherapy, Ipilimumab and Nivolumab

Head and Neck Cancer Study Project in the Geriatric Population

A Phase 2b Study to Evaluate Rezpegaldesleukin (Rezpeg) in the Treatment of Severe to Very Severe Alopecia Areata in Adult Patients (Rezolve AA)

Study to Evaluate the Efficacy and Safety of Pemigatinib in Participants With Previously Treated Glioblastoma or Other Primary Central Nervous System Tumors Harboring Activating FGFR1-3 Alterations

Observational Study Protocol: LIVER-R

Research Study Investigating How Well NDec Works in People With Sickle Cell Disease

Dose Escalation and Expansion Study to Evaluate the Safety, PK, PD and Efficacy of ZE46-0134 in Adults With FLT3 Mutated or Spliceosome Mutated Relapsed or Refractory Acute Myeloid Leukemia

Acute Hip Fracture Study in Patients 65 Years or Greater

A Study of Radiation Dosimetry, Safety, and Tolerability of Extended Lutetium (177Lu) Vipivotide Tetraxetan Treatment in Chemo-naïve Adults With Metastatic Castration-resistant Prostate Cancer: RADIOpharmaceutical DOSimetry Evaluation (RADIODOSE) Study

Diabetes-Centered Evaluation of Revascularization Strategy of Functional and Imaging-CombiNEd State-of-the-Art Percutaneous Coronary Intervention or Coronary-Artery Bypass Grafting in Patients With Diabetes Mellitus and Multivessel Coronary Artery Disease