Clinical Trials in Boston

Showing 9341-9360 of 13,548 trials

A Long-Term Extension Study of AT2101 (Afegostat Tartrate) in Type 1 Gaucher Patients

NCT00813865

This study evaluated the long-term safety and efficacy of afegostat tartrate in participants with Gaucher disease who were enrolled in a previous Phase 2 study of afegostat tartrate.

Gaucher DiseaseType 1 Gaucher DiseaseGaucher Disease, Type 1

Amicus Therapeutics8 participantsStarted May 2009

Coral Springs, Florida, United States • Decatur, Georgia, United States • Boston, Massachusetts, United States +1 more locations

COMPLETEDPhase 2< 1 mile

A Study of Oral AT2101 (Afegostat Tartrate) in Treatment-naive Patients With Gaucher Disease

NCT00446550

This study evaluated the safety and tolerability of afegostat tartrate in participants with type 1 Gaucher disease who were not receiving enzyme replacement therapy (ERT) or substrate reduction therapy (SRT).

Gaucher DiseaseType 1 Gaucher DiseaseGaucher Disease, Type 1

Amicus Therapeutics19 participantsStarted Jun 2008

Beverly Hills, California, United States • Coral Springs, Florida, United States • Decatur, Georgia, United States +8 more locations

COMPLETEDPhase 2< 1 mile

Everolimus (RAD001) for Children With Chemotherapy-Refractory Progressive or Recurrent Low-Grade Gliomas

NCT00782626

The purpose of this research study is to learn if the study drug RAD001 can shrink or slow the growth of low-grade gliomas. Additionally, the safety of RAD001 will be studied. RAD001 is a drug that may act directly on tumor cells by inhibiting tumor cell growth and proliferation.

GliomaLow-grade GliomaAstrocytoma

Dana-Farber Cancer Institute23 participantsStarted Jun 2009

Phoenix, Arizona, United States • Denver, Colorado, United States • Gainesville, Florida, United States +7 more locations

A Long-Term Extension Study of AT2101 (Afegostat Tartrate) in Type 1 Gaucher Patients

A Study of Oral AT2101 (Afegostat Tartrate) in Treatment-naive Patients With Gaucher Disease

Everolimus (RAD001) for Children With Chemotherapy-Refractory Progressive or Recurrent Low-Grade Gliomas

Find Trials by Condition in Boston

Dabrafenib in Treating Patients With Solid Tumors and Kidney or Liver Dysfunction

A Pilot Intervention With Families of Children With Special Health Care Needs

Closed-Loop Insulin Delivery in Children Less Than 7 Years of Age

Comparison of Two Behavioral Treatments for Stress Reduction

The Use of Certolizumab Pegol for Treatment of Active Crohn's Disease in Children and Adolescents

Connecticut Child STEPs

A Placebo Controlled Study of MR901 (Talaporfin Sodium Sodium + a Drug-activating Device) for the Relief of Lower Urinary Tract Symptoms Due to Benign Prostatic Hyperplasia

Smoking Cessation Study In Healthy Adolescent Smokers

A Clinical Decision Support Tool for Electronic Health Records

Exenatide Study of Cardiovascular Event Lowering Trial (EXSCEL): A Trial To Evaluate Cardiovascular Outcomes After Treatment With Exenatide Once Weekly In Patients With Type 2 Diabetes Mellitus

Phase II Study of Buparlisib + Docetaxel in Advanced or Metastatic Squamous Non-small Cell Lung Cancer (NSCLC) Patients

Efficacy and Safety of TBS-2 Testosterone Gel in Women With Acquired Female Orgasmic Disorder

Transfusion Requirements in Cardiac Surgery III

SOLUTION: Study of Oral Liprotamase Unit-Matched Therapy Of Non-Porcine Origin in Patients With Cystic Fibrosis

Study Evaluating Neratinib (HKI-272) In Combination With Vinorelbine In Subjects With Solid Tumors And Metastatic Breast Cancer

A Study of a Combination of Trastuzumab and Capecitabine With or Without Pertuzumab in Patients With HER2-positive Metastatic Breast Cancer (PHEREXA)

Two Part Study to Evaluate Pharmacokinetics, Safety, and Antiviral Activity of Elvitegravir Administered With a PI/r Background Regimen for ARV Treatment-Experienced Pediatric Participants