Manipulating the Microbiome in IBD by Antibiotics and FMT

Exclusion Criteria

• •Change in dose or intervals of anti-TNF within the past 2 months prior to admission.
• •Disease confined to the rectum (Proctitis).
• •Antibiotic use in the past 4 weeks.
• •Any known erosive inflammation anywhere in the small bowel or esophagus.
• •Any proven infection such as positive stool culture, parasite or C. difficile, urinary tract infection, cellulitis, abscess, pneumonia, line-infections etc.
• •Fever \>38.5, or \>38.0c thought to be unrelated to the inflammatory process of active UC.
• •The probable need for second line medical therapy (infliximab, cyclosporine, tacrolimus) or colectomy within 5 days of enrollment, as judged by the caring physician.
• •Known allergy to more than one antibiotic regimen from the list below.
• •Pregnancy.