Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Shaare Zedek Medical Center
Age
2–75
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Children over the age the 2 years and adults of all ages with established diagnosis of UC using standard criteria (26, 27).
Admission for IV steroid therapy
PUCAI of at least 65 points at admission (i.e. severe attack)
PUCAI\>45 at enrollment
Ability to swallow antibiotics (pills or syrup)
You may not be if
Change in dose or intervals of anti-TNF within the past 2 months prior to admission.
Disease confined to the rectum (Proctitis).
Antibiotic use in the past 4 weeks.
Any known erosive inflammation anywhere in the small bowel or esophagus.
Any proven infection such as positive stool culture, parasite or C. difficile, urinary tract infection, cellulitis, abscess, pneumonia, line-infections etc.
Fever \>38.5, or \>38.0c thought to be unrelated to the inflammatory process of active UC.
The probable need for second line medical therapy (infliximab, cyclosporine, tacrolimus) or colectomy within 5 days of enrollment, as judged by the caring physician.
Known allergy to more than one antibiotic regimen from the list below.
Pregnancy.
Clareo Health | Manipulating the Microbiome in IBD by Antibiotics and FMT