Clinical Trials in Boston

Showing 6541-6560 of 13,548 trials

Digitally Assisted Recovery Coach

NCT05393544

The aims of this proof-of-concept study are to determine the feasibility of 1) using a smartphone app ("Lifeguard") to facilitate engagement with a peer recovery coach, 2) monitoring post-detox using a modified Brief Addiction Monitor, and 3) assessing linkage to care post-detox.

Alcohol Use DisorderAlcohol Withdrawal

Brigham and Women's Hospital10 participantsStarted Nov 2021

Boston, Massachusetts, United States

COMPLETEDPhase 3< 1 mile

Radiation Therapy With or Without Optional Tamoxifen in Treating Women With Ductal Carcinoma in Situ

NCT00003857

RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. Estrogen can stimulate the growth of breast cancer cells. Hormone therapy using tamoxifen may fight breast cancer by blocking the uptake of estrogen by the tumor cells. It is not yet known if radiation therapy is more effective than observation, with or without tamoxifen, in treating ductal carcinoma in situ. PURPOSE: Randomized phase III trial to compare the effectiveness of radiation therapy with that of observation, with or without tamoxifen, in treating women who have ductal carcinoma in situ.

Breast Cancer

Radiation Therapy Oncology Group636 participantsStarted Dec 1999

Mobile, Alabama, United States • Fairbanks, Alaska, United States • Phoenix, Arizona, United States +366 more locations

Digitally Assisted Recovery Coach

Radiation Therapy With or Without Optional Tamoxifen in Treating Women With Ductal Carcinoma in Situ

Find Trials by Condition in Boston

Long-Term Treatment and Follow up of Subjects Completing 24 Months of Treatment With Tesevatinib on Study KD019-101

Safety and Efficacy of ATIR101 as Adjunctive Treatment to Blood Stem Cell Transplantation From a Haploidentical Family Donor Compared to Post-transplant Cyclophosphamide in Patients With Blood Cancer

A Study to Evaluate Efficacy and Safety of AG-348 in Not Regularly Transfused Adult Participants With Pyruvate Kinase Deficiency (PKD)

Combination Chemotherapy With or Without Hypofractionated Radiation Therapy Before Surgery in Treating Patients With Pancreatic Cancer

Memory Aid by Intranasal Insulin in Diabetes (MemAID)

Kidney Precision Medicine Project

A Study Evaluating CPI-1205 in Patients With B-Cell Lymphomas

Safety and Efficacy of NBI-98854 in Pediatric Subjects With Tourette Syndrome

CHoice of OptImal transCatheter trEatment for Mitral Insufficiency Registry

Struvite Stones Antibiotic Study

Adherence With Continuous-dose Oral Contraceptive: Evaluation of Self-Selection and Use

Neoadjuvant Therapy in Clinical Stage I-III HER2-positive Breast Cancer.

Efficacy and Safety of Vedolizumab Subcutaneously (SC) as Maintenance Therapy in Ulcerative Colitis

Gene Transfer Clinical Study in Crigler-Najjar Syndrome

Phenotypes, Biomarkers and Pathophysiology in Spastic Ataxias

A Study to Investigate the Safety and Efficacy of Emapalumab, an Anti-IFN-gamma mAb in Patients With Systemic Juvenile Idiopathic Arthritis (sJIA) or Adult-onset Still's Disease (AOSD) Developing Macrophage Activation Syndrome/Secondary HLH (MAS/sHLH)

Objective Pain Measurement Using a Wearable Biosensor and a Mobile Platform in Patients With Endometriosis

First in Human Testing of Dose-escalation of SAR440234 in Patients With Acute Myeloid Leukemia, Acute Lymphoid Leukemia and Myelodysplastic Syndrome