Clinical Trials in Boston

Showing 6521-6540 of 13,548 trials

Study to Determine the Dose, the Safety and Effectiveness of a New Drug, Modified Release rhTSH, in Patients With Multinodular Goiter

NCT00454220

The purpose of this study is to determine the safety and effectiveness of 2 different doses of modified-release recombinant human thyroid stimulating hormone (MRrhTSH) when administered with radioiodine in patients with multinodular goiter, a condition that involves the enlargement of the thyroid gland. We will also evaluate the safety and effectiveness of radioiodine therapy alone in these patients. The goal of the treatment is to determine if there was a reduction in the size of the goiter and to study if goiter symptoms have improved after 6 months and after 36 months.

Multinodular Goiter

Genzyme, a Sanofi Company96 participantsStarted Jul 2007

Boston, Massachusetts, United States • Curitiba, Brazil • Rio de Janeiro, Brazil +8 more locations

UNKNOWN< 1 mile

Prevalence of Sleep Apnea and Atrial Fibrillation

NCT05155813

The investigators will screen consecutive patients presenting to the atrial fibrillation clinic for sleep apnea using a FDA-approved home sleep testing device, WatchPAT to determine prevalence of sleep apnea in a clinic-based sample.

Sleep ApneaAtrial Fibrillation

Brigham and Women's Hospital300 participantsStarted Feb 2022

Boston, Massachusetts, United States

COMPLETED< 1 mile

A Multicenter Observational Study to Evaluate the Effectiveness of Patisiran in Patients With Polyneuropathy of ATTRv Amyloidosis With a V122I or T60A Mutation

NCT04201418

To evaluate the effectiveness of patisiran in patients with ATTRv amyloidosis with polyneuropathy who have a V122I or T60A mutation.

Hereditary Transthyretin-mediated (ATTRv) AmyloidosisPolyneuropathy

Alnylam Pharmaceuticals67 participantsStarted Dec 2019

Los Angeles, California, United States • San Diego, California, United States • Aurora, Colorado, United States +24 more locations

Study to Determine the Dose, the Safety and Effectiveness of a New Drug, Modified Release rhTSH, in Patients With Multinodular Goiter

Prevalence of Sleep Apnea and Atrial Fibrillation

A Multicenter Observational Study to Evaluate the Effectiveness of Patisiran in Patients With Polyneuropathy of ATTRv Amyloidosis With a V122I or T60A Mutation

Find Trials by Condition in Boston

Aspirin and Zileuton and Biomarker Expression in Nasal Tissue of Current Smokers

Diagnostic and Prognostic Biomarkers for Childhood Bacterial Pneumonia

3D Virtual Planning for Tibial Plateau Fractures

Robot-Assisted Therapy and Motor Learning: An Active Learning Program for Stroke

Shared Decision Aid for Post-Total Knee Arthroplasty Opioid Prescribing

A Text Messaging (SMS) Intervention to Improve Adherence to Stimulant Medications in Children With ADHD

Combination Entecavir and Peginterferon Therapy in HBeAg-Positive Immune-Tolerant Adults With Chronic Hepatitis B

Pilot Study of Biopsy Scanner for Evaluation of Bronchoscopic Small Biopsy Specimens to Determine Adequacy

Comparative Study of the Topcon Tonometers CT-800 and TRK-2P and the Haag-Streit Goldmann Manual Tonometer and Topcon SP-1P

Comparative Study of Non-contact Tonometers for Intraocular Pressure and Corneal Cell Thickness Measurements

Comparative Study of Specular Microscopes for Endothelial and Corneal Cell Measurements

An Evaluation of the Clinical Utility and Safety of the Visant Medical Canalicular Plug

Study To Assess A Radiofrequency Microneedling Device For Dermatologic Conditions

Trial of Intraperitoneal (IP) Oxaliplatin in Combination With Intravenous FOLFIRI

Treatments for Improving Mood in Depressed Teens-3

BrUOG 295: Adjuvant FOLFOX-A For Resected Pancreatic Cancer: A Phase II Brown University Oncology Research Group Trial

Study of the Safety and Efficacy of Elagolix in Women With Polycystic Ovary Syndrome