Clinical Trials in Boston

Showing 5541-5560 of 17,836 trials

P-PSMA-101 CAR-T Cells in the Treatment of Subjects With Metastatic Castration-Resistant Prostate Cancer (mCRPC) and Advanced Salivary Gland Cancers (SGC)

NCT04249947

An open-label, multi-center, single and cyclic ascending dose study of P-PSMA-101 autologous CAR-T cells in patients with mCRPC and SGC.

Prostatic Neoplasms, Castration-ResistantNeoplasms by Histologic TypeNeoplasms, Prostate+14 more

Poseida Therapeutics, Inc.40 participantsStarted Feb 2020

Duarte, California, United States • San Diego, California, United States • San Francisco, California, United States +7 more locations

COMPLETEDNA< 1 mile

SibACCESS: Developing a Telehealth Intervention to Address Unmet Psychosocial Needs of Siblings of Children With Cancer

NCT04889755

This study aims to address barriers to psychosocial care for siblings of children with cancer by piloting a group-based telehealth program for adolescent siblings of youth with cancer. The pilot trial will be preceded by a treatment development stage during which study staff will interview English- and Spanish-speaking families and psychosocial providers to assess preferences for program content, format, timing, and cultural feasibility and acceptability, while considering ideas to minimize participation barriers. Information from interviews will inform any revisions to the proposed pilot program. Then, the new SibACCESS program will be tested with a small group of families located in Massachusetts, Delaware, or Rhode Island using video-teleconferencing technology. Families will complete exit interviews to assess program acceptability and perceived benefits.

SiblingsChildhood CancerPediatric Cancer+1 more

Boston University Charles River Campus6 participantsStarted Feb 2023

Boston, Massachusetts, United States

P-PSMA-101 CAR-T Cells in the Treatment of Subjects With Metastatic Castration-Resistant Prostate Cancer (mCRPC) and Advanced Salivary Gland Cancers (SGC)

SibACCESS: Developing a Telehealth Intervention to Address Unmet Psychosocial Needs of Siblings of Children With Cancer

Find Trials by Condition in Boston

MCT for the Harvard/UCSF ROBIN Center

Safety and Effectiveness of the MiniMed™ 780G System With DS5 CGM

RAD001 and Neurocognition in PTEN Hamartoma Tumor Syndrome

A Study of KB-0742 in Participants With Relapsed or Refractory Solid Tumors Including Platinum Resistant High Grade Serous Ovarian Cancer (HGSOC)

Mapping the Genotype, Phenotype, and Natural History of Phelan-McDermid Syndrome

Neuroblastoma Precision Trial

Effect of Using Placental Membranes on Healing and Post-op Pain After Gum Surgery

TAC T-cells for the Treatment of Claudin 18.2 Positive Solid Tumors (TACTIC-3)

Study of the Efficacy of Lurasidone in Cognitive Functioning in Bipolar Patients

Schedule Intervention to Increase Sustainable Walking Activity in Midlife Working Adults

Evaluation of Brimonidine Tartrate/Ketotifen Fumarate Combination for the Treatment of Allergic Conjunctivitis

A Study to Assess the Safety, Tolerability and Efficacy of IONIS-AGT-LRx in Hypertensive Participants With Uncontrolled Blood Pressure

BioProtect Balloon Implant™ Balloon System Pivotal Study BP-007

Evaluation of the Safety and Effectiveness of Bilateral Exablate Ablation of the Pallidothalamic Tract (PTT) for the Treatment of the Motor Complications of Parkinson's Disease (PD)

A Study to Assess the Pharmacodynamics of VK0214 in Male Subjects With AMN

A Safety, Tolerability, and Efficacy Study of BMN 190 in Pediatric Patients < 18 Years of Age With CLN2 Disease

A Phase 1b Study of Imvotamab in Moderate to Severe Rheumatoid Arthritis

A Study of Lumasiran in Infants and Young Children With Primary Hyperoxaluria Type 1