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RAD001 and Neurocognition in PTEN Hamartoma Tumor Syndrome | Clinical Trials | Clareo Health

COMPLETEDPhase 1/2

RAD001 and Neurocognition in PTEN Hamartoma Tumor Syndrome

A Randomized Double-Blind Controlled Trial of Everolimus in Individuals With PTEN Mutations (RAD001XUS257T)

NCT02991807•Boston Children's Hospital

View on ClinicalTrials.gov

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Conditions

PTEN Gene MutationPTEN Hamartoma Tumor Syndrome

Interventions

RAD001

Placebo

Locations

United States

Locations (3)

Stanford University

Palo Alto, California, United States

Boston Children's Hospital

Boston, Massachusetts, United States

Cleveland Clinic

Cleveland, Ohio, United States

Key Dates

Start Date

June 12, 2017

Primary Completion Date

February 18, 2021

Completion Date

December 22, 2021

Last Updated

February 17, 2025

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Sponsors

Lead Sponsor

Boston Children's Hospital

Collaborators

National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
Office of Rare Diseases (ORD)
National Center for Advancing Translational Sciences (NCATS)
Novartis Pharmaceuticals
PTEN Research
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

Detailed Description

Full Eligibility Criteria

Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: February 17, 2025Data synced to Clareo: April 27, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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