Clinical Trials in Boston

Showing 5561-5580 of 13,548 trials

Pyruvate Kinase (PK) Deficiency Global Longitudinal Registry: Patient-Reported Outcomes (PRO)

NCT04964323

The primary objective of this study is to understand and characterize the health-related quality of life (HRQoL) and disease burden of adult participants with PK deficiency receiving routine clinical care. This study is an observational (i.e., noninterventional), longitudinal, multicenter, global registry for participants with PK deficiency, a rare nonspherocytic hemolytic anemia. This study will be open for enrollment for 2 years and all enrolled participants will be followed prospectively for up to 96 weeks. Data will be collected from participants who have provided informed consent and authorization pursuant to applicable laws and regulations.

Pyruvate Kinase DeficiencyPyruvate Kinase Deficiency AnemiaAnemia+1 more

Agios Pharmaceuticals, Inc.15 participantsStarted Jul 2021

Boston, Massachusetts, United States • Milan, Italy • Utrecht, Netherlands +2 more locations

WITHDRAWNPhase 1/2< 1 mile

Safety and Immunotherapeutic Activity of Cemiplimab in Participants With HBV on Suppressive Antiviral Therapy

NCT04046107

The purpose of this study is to evaluate the safety and immunotherapeutic activity of cemiplimab in participants with hepatitis B virus (HBV) on suppressive antiviral therapy.

Hepatitis B Virus

National Institute of Allergy and Infectious Diseases (NIAID)Started Jan 2024

San Francisco, California, United States • Atlanta, Georgia, United States • Boston, Massachusetts, United States +5 more locations

Pyruvate Kinase (PK) Deficiency Global Longitudinal Registry: Patient-Reported Outcomes (PRO)

Safety and Immunotherapeutic Activity of Cemiplimab in Participants With HBV on Suppressive Antiviral Therapy

Find Trials by Condition in Boston

A Study of Duvelisib in Participants With Refractory Indolent Non-Hodgkin Lymphoma

Low-Dose Atropine for Treatment of Myopia

Mifepristone and Misoprostol for Undesired Pregnancy of Unknown Location

Intermittent Hypoxia and Caffeine in Infants Born Preterm

Clinical Validation of An Optimized Multi-Target Stool DNA (Mt-sDNA 2.0) Test, for Colorectal Cancer Screening "BLUE-C"

Radiation-Free Technique for Evaluating Renal Scarring (RAFTERS)

Diagnostic Study of Patients With Acute Lymphoblastic Leukemia or Acute Promyelocytic Leukemia

Dociparstat Sodium (CX-01) Combined With Standard Induction Therapy for Newly Diagnosed Acute Myeloid Leukemia

Investigation to Minimize Prolapse Recurrence of the Vagina Using Estrogen

Efficacy and Safety Study of the Use of Benralizumab for Patients With Moderate to Severe Atopic Dermatitis

Observation or Radiation Therapy in Treating Patients With Grade I, Grade II, or Grade III Meningioma

Efficacy and Safety of Orally Administered BBT-401-1S in Subjects With Ulcerative Colitis

Study to Assess the Efficacy and Safety of Rilonacept Treatment in Participants With Recurrent Pericarditis

A Long-Term Extension Trial in Participants With Atopic Dermatitis Who Participated in Previous EDP1815 Trials

Evidence-based Stimulation Trial With Human rFSH in Europe and Rest of World 2

First-In-Man Study for an Ophthalmic Synthetic Tissue Substitute

Dose-Ranging Efficacy and Safety Study of Topical Rapamycin Cream for Facial Angiofibroma Associated With Tuberous Sclerosis Complex

Study of Emerfetamab (AMG 673) in Adults With Relapsed/Refractory Acute Myeloid Leukemia (AML)