Clinical Trials in Boston

Showing 4261-4280 of 17,836 trials

Study of RMC-9805 in Participants With KRAS G12D-Mutant Solid Tumors

NCT06040541

This study is to evaluate the safety and tolerability of RMC-9805 as monotherapy and in combination with RMC-6236 in adults with KRAS G12D-mutant solid tumors.

Non-small Cell Lung Cancer (NSCLC)Colorectal Cancer (CRC)Pancreatic Ductal Adenocarcinoma (PDAC)+1 more

Revolution Medicines, Inc.604 participantsStarted Sep 2023

Sacramento, California, United States • New Haven, Connecticut, United States • Sarasota, Florida, United States +14 more locations

COMPLETEDPhase 2< 1 mile

A Phase II Study of Eribulin and Pembrolizumab in Soft Tissue Sarcomas

NCT03899805

This research study is studying a combination of drugs (chemotherapy + Immunotherapy) as a possible treatment for liposarcoma, leiomyosarcoma, or undifferentiated pleomorphic sarcoma that has spread and has not responded to standard treatment.

SarcomaLiposarcomaLeiomyosarcoma+1 more

Dana-Farber Cancer Institute57 participantsStarted Jun 2019

Boston, Massachusetts, United States • Boston, Massachusetts, United States

Study of RMC-9805 in Participants With KRAS G12D-Mutant Solid Tumors

A Phase II Study of Eribulin and Pembrolizumab in Soft Tissue Sarcomas

Find Trials by Condition in Boston

A Study to Evaluate the Safety and Efficacy of NG101 in Adult Participants With Symptomatic Diabetic or Idiopathic Gastroparesis

Symptom Management Implementation of Patient Reported Outcomes in Oncology

A Study of Mirvetuximab Soravtansine vs. Investigator's Choice (IC) of Chemotherapy in Platinum-Resistant, Advanced High-Grade Epithelial Ovarian, Primary Peritoneal, or Fallopian Tube Cancers With High Folate Receptor-Alpha (FRα) Expression

Efficacy & Safety Study of Bilateral IVT Injection of GS010 in LHON Subjects Due to the ND4 Mutation for up to 1 Year

The Diabetes Prevention Program Outcomes Study AD/ADRD Project

Life-Steps Counseling to Enhance Adherence and Engagement in PrEP Care

Clinical and Basic Investigations Into Congenital Disorders of Glycosylation

Perioperative Pembrolizumab (MK-3475) Plus Neoadjuvant Chemotherapy Versus Perioperative Placebo Plus Neoadjuvant Chemotherapy for Cisplatin-eligible Muscle-invasive Bladder Cancer (MIBC) (MK-3475-866/KEYNOTE-866)

Study of Uterine Prolapse Procedures - Randomized Trial

The Rhode Island Prescription and Illicit Drug Study

A Study Assessing Adverse Events and Disease Activity When Comparing Intravenously (IV) Infused ABBV-400 to Trifluridine and Tipiracil (LONSURF) Oral Tablets Plus IV Infused Bevacizumab in Adult Participants With c-Met Protein Above Cutoff Level Above Refractory Metastatic Colorectal Cancer

Acalabrutinib, Obinutuzumab and Chlorambucil in Treatment naïve CLL

A Study to Evaluate AB308 in Combination With AB122 in Participants With Advanced Malignancies

A Study to Investigate the Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD) of RO7248824 in Participants With Angelman Syndrome (AS)

Proof of Concept Study of SAR443122 in Patients With Cutaneous Lupus Erythematosus

Open-Label Extension Study for Subjects With H1 Antihistamine Refractory Chronic Spontaneous Urticaria Completing Study AK006-001

A Safety and Pharmacokinetics Study of IDP-122 Lotion in Pediatric Participants With Plaque Psoriasis

Multicenter Study to Evaluate the Clinical Outcome of PrimeTaper EV Implant in Single Tooth Restorations