Clinical Trials in Boston

Showing 4241-4260 of 17,836 trials

Tucatinib, Trastuzumab, and Capecitabine for the Treatment of HER2+ LMD

NCT03501979

A phase 2 non-randomized study to assess the safety and efficacy of the combination of tucatinib and trastuzumab with capecitabine for the treatment of leptomeningeal metastases in HER2-neu positive breast cancer.

Metastatic Breast CancerLeptomeningeal Disease

University of Alabama at Birmingham17 participantsStarted Feb 2019

Birmingham, Alabama, United States • San Francisco, California, United States • Washington D.C., District of Columbia, United States +6 more locations

COMPLETEDPhase 3< 1 mile

Treatment of GVHD in Hematopoietic Stem Cell Transplant (HSCT) Recipients Using AAT Plus Corticosteroids (CS) Compared With Corticosteroids Alone

NCT04167514

Study CSL964\_5001 will investigate the efficacy of AAT with corticosteroids compared with corticosteroids alone as first line therapy for patients with high-risk acute GVHD

Graft Versus Host Disease (GVHD)

CSL Behring136 participantsStarted Jan 2020

Stanford, California, United States • Gainesville, Florida, United States • Tampa, Florida, United States +22 more locations

Tucatinib, Trastuzumab, and Capecitabine for the Treatment of HER2+ LMD

Treatment of GVHD in Hematopoietic Stem Cell Transplant (HSCT) Recipients Using AAT Plus Corticosteroids (CS) Compared With Corticosteroids Alone

Find Trials by Condition in Boston

Long-Term Evaluation of BIIB067 (Tofersen)

Mitral Valve Screening Survey

Genetic Testing in Screening Patients With Metastatic or Unresectable Colon or Rectal Cancer for a COLOMATE Trial

A Study of Donanemab (LY3002813) in Participants With Early Alzheimer's Disease (TRAILBLAZER-ALZ 2)

Clinical Trial of Brentuximab Vedotin in Classical Hodgkin Lymphoma

Study of RMC-9805 in Participants With KRAS G12D-Mutant Solid Tumors

A Study to Test the Effects of Riociguat in Patients With Pulmonary Hypertension Associated With Left Ventricular Systolic Dysfunction

A Study of LY3549492 in Adults With Obesity or Overweight With Type 2 Diabetes

Perioperative Pembrolizumab (MK-3475) Plus Neoadjuvant Chemotherapy Versus Perioperative Placebo Plus Neoadjuvant Chemotherapy for Cisplatin-eligible Muscle-invasive Bladder Cancer (MIBC) (MK-3475-866/KEYNOTE-866)

Effect of Evolocumab on Saphenous Vein Graft Patency Following Coronary Artery Bypass Surgery

A Study of EPX-100 (Clemizole Hydrochloride) in Participants With Dravet Syndrome

A Study of the Safety, Tolerability, and Pharmacokinetics of Dolutegravir in Neonates Exposed to HIV-1

A Study Investigating DNA-damage Response Agents in Molecularly Altered Advanced Cancer

A Study of LY3549492 in Healthy Weight Adult Participants

Multimodal Intervention for Cachexia in Advanced Cancer Patients Undergoing Chemotherapy

A Study of Two Different Doses of Cabozantinib (XL184) in Progressive, Metastatic Medullary Thyroid Cancer

A Study of Setanaxib Co-Administered With Pembrolizumab in Patients With Recurrent or Metastatic Squamous Cell Carcinoma of Head and Neck (SCCHN)

Multicenter Study to Evaluate the Clinical Outcome of PrimeTaper EV Implant in Single Tooth Restorations