Clinical Trials in Boston

Showing 4081-4100 of 17,836 trials

Improving Memory in Alzheimer's Disease With Noninvasive Brain Stimulation

NCT06094192

The investigators will evaluate the theory that Alzheimer's disease-related memory impairment derives from the inefficient orchestration of rhythmic activity at the level of large-scale cortical networks. The results as expected to elucidate AD-related pathophysiology and set groundwork for the development of drug-free interventions for improving memory in AD and related dementias.

Alzheimer Disease

Boston University Charles River Campus204 participantsStarted Dec 2023

Boston, Massachusetts, United States

RECRUITINGNA< 1 mile

Menstrual-phase-dependent Differences in Response to Sleep Loss

NCT05381532

This study is designed to assess how healthy premenopausal women respond to different patterns of sleep loss at different times in the menstrual cycle.

Sleep Deprivation

Brigham and Women's Hospital100 participantsStarted Oct 2022

Boston, Massachusetts, United States

Active Not RecruitingPhase 3< 1 mile

Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice and Pembrolizumab in Patients With Previously Untreated, Locally Advanced Inoperable or Metastatic Triple-Negative Breast Cancer

NCT05382286

The primary objective of this study is to compare the progression-free survival (PFS) between sacituzumab govitecan-hziy (SG) and pembrolizumab versus treatment of physician's choice (TPC) and pembrolizumab in participants with previously untreated, locally advanced inoperable or metastatic triple-negative breast cancer, whose tumors express programmed cell death ligand 1 (PD-L1).

Triple Negative Breast CancerPD-L1 Positive

Gilead Sciences443 participantsStarted Jul 2022

Anchorage, Alaska, United States • Tucson, Arizona, United States • Tucson, Arizona, United States +501 more locations

Improving Memory in Alzheimer's Disease With Noninvasive Brain Stimulation

Menstrual-phase-dependent Differences in Response to Sleep Loss

Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice and Pembrolizumab in Patients With Previously Untreated, Locally Advanced Inoperable or Metastatic Triple-Negative Breast Cancer

Find Trials by Condition in Boston

Vertical Soft Tissue Augmentation With CTG vs ADM

HLA Demographics Study in Adults With Type 1 Diabetes

Cobimetinib in Refractory Langerhans Cell Histiocytosis (LCH), and Other Histiocytic Disorders

Enhanced Local Intensified Radiation Therapy in Elderly Glioblastoma: A Phase 2 Hybrid Randomized Trial

A Pilot Clinical Trial Investigating the Effect of Cutaneous Cooling on Sebum Production

Study of Recombinant Protein Vaccines With Adjuvant as a Primary Series and as a Booster Dose Against COVID-19 in Adults 18 Years of Age and Older

Effects of Hypoglossal Nerve Stimulation on Cognition and Language in Down Syndrome and Obstructive Sleep Apnea

Study of LN-145, Autologous Tumor Infiltrating Lymphocytes in the Treatment of Patients With Cervical Carcinoma

Pragmatic Trial of Remote tDCS and Somatosensory Training for Phantom Limb Pain With Machine Learning to Predict Treatment Response

Development of Ingestible Biosensors to Enhance PrEP Adherence in Substance Users (PrEPSteps)

Efficacy and Safety of Obefazimod in Subjects With Moderately to Severely Active Crohn's Disease

Safety, Pharmacokinetics, and Preliminary Efficacy of Isatuximab in Patients Awaiting Kidney Transplantation

Phase III Radium 223 mCRPC-PEACE III

A Study to Assess Vamorolone in Becker Muscular Dystrophy (BMD)

Posaconazole (MK-5592) Intravenous and Oral in Children (<2 Years) With Invasive Fungal Infection (MK-5592-127)

Study of FIH of STX-241 in Locally Advanced or Metastatic NSCLC Resistant to EGFR TKIs

Global Trial in APG2575 for Patients With CLL/SLL