Clinical Trials in Boston

Showing 3621-3640 of 11,609 trials

Cabozantinib and Nivolumab for Carcinoid Tumors

NCT04197310

This research study, is studying the combination of cabozantinib and nivolumab in treating advanced carcinoid tumors. \- Carcinoid tumor is another term used to refer to neuroendocrine tumors that arise in organs such as the gastrointestinal tract, lungs, or thymus.

Carcinoid TumorCarcinoid Tumor of GI SystemNeuroendocrine Tumors

Dana-Farber Cancer Institute19 participantsStarted Dec 2019

Boston, Massachusetts, United States • Boston, Massachusetts, United States

Active Not RecruitingPhase 3< 1 mile

HERTHENA-Lung02: A Study of Patritumab Deruxtecan Versus Platinum-based Chemotherapy in Metastatic or Locally Advanced EGFRm NSCLC After Failure of EGFR TKI Therapy

NCT05338970

Disease progression is typical for patients with epidermal growth factor receptor mutated (EGFRm) non-small cell lung cancer (NSCLC). Standard platinum-based chemotherapy offers limited efficacy and an unfavorable safety profile.There is an urgent need for more effective and tolerable therapies for patients with EGFRm NSCLC who have exhausted available targeted therapies. Clinical evidence suggest that patritumab deruxtecan constitutes a promising investigational therapy for patients with EGFRm NSCLC.

Nonsquamous Non-small Cell Lung CancerEGFR L858REGFR Exon 19 Deletion

Daiichi Sankyo586 participantsStarted Jul 2022

Anchorage, Alaska, United States • Springdale, Arkansas, United States • Duarte, California, United States +179 more locations

Cabozantinib and Nivolumab for Carcinoid Tumors

HERTHENA-Lung02: A Study of Patritumab Deruxtecan Versus Platinum-based Chemotherapy in Metastatic or Locally Advanced EGFRm NSCLC After Failure of EGFR TKI Therapy

Find Trials by Condition in Boston

Phase 2 Platform Study in Patients With Advanced Non-Small Lung Cancer Who Progressed on First-Line Osimertinib Therapy (ORCHARD)

MBCT Via Group Videoconferencing for Acute Coronary Syndrome Patients With Depressive Symptoms: A Pilot RCT

The PROMISE Study: Duavee in Women With DCIS

Fluoxetine for Obsessive-Compulsive Disorder in Children and Adolescents With Bipolar Disorder

A Natural History Study of Biomarkers and Clinical Outcomes in Mucopolysaccharidosis Type IIIA (MPS IIIA; Sanfilippo Syndrome)

B244 Topical Spray for the Treatment of Pruritus in Adults With a History of Atopic Dermatitis

Trilaciclib in Patients Receiving Sacituzumab Govitecan-hziy for Triple Negative Breast Cancer

Trastuzumab Deruxtecan With Nivolumab in Advanced Breast and Urothelial Cancer

A Study of Loncastuximab Tesirine and Rituximab (Lonca-R) in Previously Untreated Unfit/Frail Participants With Diffuse Large B-cell Lymphoma (DLBCL)

Study of the Safety, Tolerability, Pharmacokinetics and Biomarker of DONQ52 in Celiac Disease Patients

A Study of Acute Respiratory Infections in Global Outpatient Setting

Study of the Safety and Efficacy of MR-100A-01 in Approximately 1200 Healthy Women for up to 13 Cycles

Avelumab in First-line NSCLC (JAVELIN Lung 100)

A Dose Finding Study of ZW49 in Patients With HER2-Positive Cancers

Multi-Center Study on Performance of the Ponto Implant System Using Minimally Invasive Ponto Surgery (in Adult Patients)

A Randomized Controlled Trial of TNK-tPA Versus Standard of Care for Minor Ischemic Stroke With Proven Occlusion

A Study on the Immune Response and Safety of an Adjuvanted Human Papillomavirus Vaccine When Given to Healthy Women 16 to 26 Years of Age

Efficacy and Safety of GWP42003-P Oral Solution in Children With Epilepsy With Myoclonic-atonic Seizures