Clinical Trials in Boston

Showing 2241-2260 of 17,836 trials

Single Use Bronchoscopes for Interventional Pulmonology

NCT06596655

The goal of this pilot single-arm crossover trial is to investigate the feasibility and safety of using single-use flexible bronchoscopes (SUFB) for routine diagnostic and therapeutic interventional pulmonary procedures instead of reusable flexible bronchoscopes (RFB). The main questions it aims to answer are: Was a decision to crossover from SUFB to RFB (at the discretion of the clinical bronchoscopist) made ? Bronchoscopist's assessment of the SUFB for each procedure (using a Likert scale 0-10) including: 1. Overall assessment 2. Scope quality 3. Scope handling 4. Scope maneuverability 5. Tool compatibility 6. Suction 7. Lavage 8. Safety 9. Image quality Participants will undergo bronchoscopy with single use bronchoscopes.

Bronchoscopic Interventions

Beth Israel Deaconess Medical Center20 participantsStarted May 2025

Boston, Massachusetts, United States

RECRUITINGPhase 1< 1 mile

Study of ONO-4685 in Patients With Relapsed or Refractory T Cell Lymphoma

NCT05079282

This study will investigate the safety, tolerability, pharmacokinetics, and preliminary efficacy of ONO-4685 in patients with relapsed or refractory T cell Lymphoma

Relapsed or Refractory T Cell Lymphoma

Ono Pharmaceutical Co., Ltd.217 participantsStarted Dec 2021

Birmingham, Alabama, United States • Duarte, California, United States • Orange, California, United States +17 more locations

Single Use Bronchoscopes for Interventional Pulmonology

Study of ONO-4685 in Patients With Relapsed or Refractory T Cell Lymphoma

Find Trials by Condition in Boston

Transcranial Magnetic Stimulation (TMS) in Obsessive Compulsive Disorder (OCD): Mechanisms and Biomarkers

A Study to Assess Disease Activity and Safety of Subcutaneous Lutikizumab (ABT-981) in Adult Participants With Moderate to Severe Hidradenitis Suppurativa Who Have Failed Anti-Tumor Necrosis Factor (TNF) Therapy and Who Are Naïve to Biologic Therapy

Supporting Our Caregivers In ADRD Learning (SOCIAL)

Eliminating Monitor Overuse Trial (EMO Trial)

Safety, Tolerability, PK, and PD Study of PGN-EDODM1 in Participants With Myotonic Dystrophy Type 1

Interaction of Melatonin and MTNR1B Genotype on Glucose Control - Study 1

Esophageal Cancer Multimodal Prehabilitation Study

Study of Bitopertin in Participants With EPP or XLP (APOLLO)

VOICE-Early Response to Vedolizumab and IL-23 Antagonists in Participants With Crohn's Disease: A Prospective Observational Study

Long-term Safety and Efficacy of Leniolisib in PIDs With Immune Dysregulation

A Study of Guselkumab Subcutaneous Therapy in Participants With Moderately to Severely Active Crohn's Disease

VK2735 for Weight Management Type 2 Diabetes Phase 3 (VANQUISH 2)

A Global Phase III Study of Rilvegostomig or Pembrolizumab Plus Chemotherapy for First-Line Treatment of Metastatic Non-squamous NSCLC

Clinical Study of Chondro-Gide® for Large Chondral Lesions in the Knee

A Study to Investigate the Effect on Lung Function of BDA Formulated With a Next Generation Propellant Compared With an Approved Asthma Treatment (BDA With HFA Propellant) in Participants With Asthma

A Study of Aticaprant 10 Milligrams (mg) as Adjunctive Therapy in Adult Participants With MDD With Moderate-to-severe Anhedonia and Inadequate Response to Current Antidepressant Therapy

A Study of TAK-360 in Adults With Narcolepsy Without Cataplexy (NT2)

SPI-62 as a Treatment for Hypercortisolism Related to a Benign Adrenal Tumor