Clinical Trials in Boston

Showing 2221-2240 of 17,836 trials

Assess Long-Term Safety of Danicopan Add-on Therapy in Participants With Paroxysmal Nocturnal Hemoglobinuria: Analysis of IPIG-Registry Data

NCT07413250

This is a noninterventional registry-based cohort study utilizing data collected on danicopan-treated patients with paroxysmal nocturnal hemoglobinuria (PNH) through the International PNH Interest Group (IPIG) PNH registry. The primary objectives seek to characterize the long-term safety profile of danicopan as add-on therapy to ravulizumab/eculizumab in participants with PNH.

Paroxysmal Nocturnal HemoglobinuriaPNH

Alexion Pharmaceuticals, Inc.50 participantsStarted Jan 2026

Boston, Massachusetts, United States

Active Not Recruiting< 1 mile

REgiStry Of the NAtural History of recurreNt periCarditis in pEdiatric and Adult Patients

NCT04687358

The registry will focus on furthering the understanding of the natural history of recurrent pericarditis (RP), as well as document RP-related clinical, health-related quality of life (HRQoL), and economic burden and will assist the medical community to refine or develop data-driven recommendations for clinical management of RP patients to optimize clinical outcomes. It also aims to generate data in support of the impact of rilonacept on clinical outcomes in a real-world population.

Recurrent Pericarditis

Kiniksa Pharmaceuticals International, plc500 participantsStarted Mar 2021

Anchorage, Alaska, United States • Tucson, Arizona, United States • La Jolla, California, United States +26 more locations

Assess Long-Term Safety of Danicopan Add-on Therapy in Participants With Paroxysmal Nocturnal Hemoglobinuria: Analysis of IPIG-Registry Data

REgiStry Of the NAtural History of recurreNt periCarditis in pEdiatric and Adult Patients

Find Trials by Condition in Boston

Assessment of the Efficacy and Safety of Olaparib Monotherapy Versus Physicians Choice Chemotherapy in the Treatment of Metastatic Breast Cancer Patients With Germline BRCA1/2 Mutations.

Study of the CDK4/6 Inhibitor Palbociclib (PD-0332991) in Combination With the PI3K/mTOR Inhibitor Gedatolisib (PF-05212384) for Patients With Advanced Squamous Cell Lung, Pancreatic, Head & Neck and Other Solid Tumors

Specialized Pro-resolving Lipid Mediators and Treatment Resistant Depression

TIL Therapy in cSCC and MCC

Study to Assess Safety, Efficacy and Persistence of ACE1831, in Subjects With IgG4-Related Disease

A Study to Test if Fremanezumab is Effective in Preventing Migraine in Children and Adolescents

Acceptance and Commitment Therapy to Improve Social Support for Veterans With PTSD

Changing Lives and Changing Outcomes-9 at Worcester Recovery Center and Hospital

A Study of a Potential Disease Modifying Treatment in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation

Dominantly Inherited Alzheimer Network Trial: An Opportunity to Prevent Dementia. A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset Alzheimer's Disease Caused by a Genetic Mutation. Master Protocol DIAN-TU-001

Compassionate Use of Concizumab if You Have Haemophilia

Adult Congenital Heart Disease International EValuation of the Effectiveness of SGLT2i Registry

Post Market Clinical Follow-up (PMCF) Study of the A.L.P.S. Proximal Humerus Plating System

A Real World Study to Globally Assess Disease Burden in Adolescent and Adult Participants With Alopecia Areata, Vitiligo, or Hidradenitis Suppurativa

A Study of Atezolizumab Versus Placebo as Adjuvant Therapy in Participants With High-risk Muscle-invasive Bladder Cancer (MIBC) Who Are ctDNA Positive Following Cystectomy

5-SENSE Score Validation Study

Comparing Telephone Symptom Monitoring Interventions for Managing Symptoms and Psychological Distress During Oral Anti-Cancer Treatment

A Study Evaluating the Efficacy and Safety of Crovalimab Versus Eculizumab in Participants With Paroxysmal Nocturnal Hemoglobinuria (PNH) Not Previously Treated With Complement Inhibitors