Clinical Trials in Boston

Showing 2001-2020 of 8,503 trials

Multicenter Symphony IL-6 Monitoring Sepsis ICU Study

NCT06181604

The primary objective of this study is to establish an IL-6 concentration cutoff and optimal time point(s) for using Symphony IL-6 that predict 28-day mortality in patients who are admitted or are intended to be admitted to the intensive care unit (ICU) diagnosed with sepsis or septic shock.

SepsisSeptic Shock

Bluejay Diagnostics, Inc.143 participantsStarted Jan 2024

Boston, Massachusetts, United States • St Louis, Missouri, United States • Brooklyn, New York, United States +4 more locations

COMPLETEDEARLY Phase 1< 1 mile

Vemurafenib in Children With Recurrent/Refractory BRAF Gene V600E (BRAFV600E)-Mutant Gliomas

NCT01748149

This is a multicenter, safety and pharmacokinetic trial to determine the MTD and/or select a recommended phase 2 dose (RP2D) of vemurafenib in children with recurrent or refractory gliomas containing the BRAFV600E or BRAF Ins T mutation.

Pediatric Recurrent/Refractory BRAFV600E-mutant Gliomas

University of California, San Francisco40 participantsStarted Apr 2014

Los Angeles, California, United States • Los Angeles, California, United States • Oakland, California, United States +18 more locations

Multicenter Symphony IL-6 Monitoring Sepsis ICU Study

Vemurafenib in Children With Recurrent/Refractory BRAF Gene V600E (BRAFV600E)-Mutant Gliomas

Find Trials by Condition in Boston

A Study in Adults and Adolescents With Angelman Syndrome (STARS)

A Study of DKN-01 and Lenalidomide/Dexamethasone in Patients With Relapsed or Refractory Multiple Myeloma

A Study to Evaluate the Incidence of Clinically Suspicious Lambert-Eaton Myasthenic Syndrome (LEMS) in Subjects Diagnosed With Small Cell Lung Cancer (SCLC)

Effective Interventions to Overcome Severe Gag Reflex

Nerve Excitability in Cisplatin-Induced Peripheral Neuropathy

Study to Evaluate EP547 in Subjects With Cholestatic Pruritus Due to Primary Biliary Cholangitis or Primary Sclerosing Cholangitis

Polygenic Risk-based Detection of Subclinical Coronary Atherosclerosis and Intervention With Statin and Colchicine

A Comparison of PT027 vs PT007 Used as Needed in Participants With Asthma

Connect® MM- The Multiple Myeloma Disease Registry

Responses to Message Source and Presentation Using Psychophysiology

Phase 3 Study to Evaluate the Safety and Efficacy of Hydrocortisone Acetate Suppositories

Topical Ruxolitinib Evaluation in Chronic Hand Eczema

A Phase 3 Study to Evaluate Safety and Biomarkers of Resmetirom (MGL-3196) in Patients With Non-alcoholic Fatty Liver Disease (NAFLD), MAESTRO-NAFLD-Open-Label-Extension (MAESTRO-NAFLD-OLE)

Trial of LAVA-1207 in Patients With Therapy Refractory Metastatic Castration Resistant Prostate Cancer (mCRPC) Resistant Prostate Cancer

A Study of INCB099280 in Combination With Adagrasib in Adults With Advanced Solid Tumors Harboring a KRASG12C Mutation

Study of Inupadenant (EOS100850) With Chemotherapy as Second Line Treatment for Nonsquamous Non-small Cell Lung Cancer

Transorb™ Self-Gripping Resorbable Mesh in High-risk Subjects Undergoing Open Repair of Ventral Hernia

A Study to Evaluate LTI-03 in Newly Diagnosed Idiopathic Pulmonary Fibrosis (IPF) Patients