Rheumatoid Arthritis Clinical Trials in Philadelphia

Showing 3361-3380 of 3,895 trials

Research Study of Greater Occipital Nerve Block As A Treatment For Prolonged Migraine Attacks

NCT00329732

Greater Occipital Nerve Blocks (GONB) are a common procedure used for the treatment of headache. The GONB procedure involves a series of injections into the greater occipital nerve (a spinal nerve located at the back of your head). The purpose of this study is to determine whether GONB is effective for the treatment of prolonged migraine attacks. This study is placebo controlled, which means that half of the patients participating will receive injections of active study drug (lidocaine plus bupivicaine) and half of the patients will receive injections of saline (placebo). The study is also blinded which means that neither you nor the study staff will know whether you received active study drug or placebo. The study remains blinded only for the first 30 minutes, at which point additional treatments (including GONB) can be administered at the discretion of your treating physician. 40 patients are expected to participate in this research study. This study is being conducted at Thomas Jefferson University only.

Migraine

Thomas Jefferson University2 participantsStarted Mar 2006

Philadelphia, Pennsylvania, United States

COMPLETEDPhase 3< 1 mile

Age-Related Eye Disease Study 2 (AREDS2)

NCT00345176

Oral supplementation with the Age-Related Eye Disease Study (AREDS) formulation (antioxidant vitamins C and E, beta carotene, and zinc) has been shown to reduce the risk of progression to advanced age-related macular degeneration (AMD). Observational data suggest that increased dietary intake of lutein + zeaxanthin (carotenoids), omega-3 long-chain polyunsaturated fatty acids (docosahexaenoic acid \[DHA\] + eicosapentaenoic acid \[EPA\]), or both might further reduce this risk. AREDS2 was designed to test whether adding lutein + zeaxanthin, DHA + EPA, or lutein + zeaxanthin and DHA + EPA to the AREDS formulation might further reduce the risk of progression to advanced AMD. A secondary goal was to test the effects of eliminating beta carotene and reducing zinc dose in the AREDS formulation.

National Eye Institute (NEI)4,203 participantsStarted Sep 2006

Birmingham, Alabama, United States • Little Rock, Arkansas, United States • Beverly Hills, California, United States +88 more locations

Research Study of Greater Occipital Nerve Block As A Treatment For Prolonged Migraine Attacks

Age-Related Eye Disease Study 2 (AREDS2)

Rheumatoid Arthritis Trials in Other Cities

Effect of Inorganic Nitrates (Beetroot Juice) on Arterial Hemodynamics and Exercise Capacity

Eating RePace Study

Nitric Oxide Administration for Acute Respiratory Distress Syndrome

Stepped Preventive Care to Reduce the Impact of Acute Pediatric Injury

Effects Of GW679769 On Bladder Nerve Function And Symptoms Of Overactive Bladder In Spinal Cord Injury Patients

Phase IIa Study of Multiple Doses of AbGn-168H by iv Infusion in Moderate to Severe Chronic Plaque Psoriasis Patients

Safety and Efficacy of AFQ056 in Adolescent Patients With Fragile X Syndrome

Cediranib Maleate and Cilengitide in Treating Patients With Progressive or Recurrent Glioblastoma

CHARITE™ vs. ALIF 5-Year Follow-up

Acamprosate in Alcoholics With Comorbid Anxiety or Depression

Anti-TF Antibody (ALT-836) to Treat Septic Patients With Acute Lung Injury or Acute Respiratory Distress Syndrome

Safety and Efficacy Study of Ad2/Hypoxia Inducible Factor (HIF)-1α/VP16 Gene Transfer in Patients With Intermittent Claudication

Effect of Teriparatide on Hip Fracture Healing

Grass Observational Study

A Multi-center Study to Evaluate the Safety and Efficacy of PEP005 (Ingenol Mebutate) Gel, When Used to Treat Actinic Keratoses on Non-head Locations (Trunk and Extremities)

Re-Engineering Systems for the Primary Care Treatment for PTSD

A Study of Retreatment With MabThera (Rituximab) in Combination With Methotrexate in Patients With Rheumatoid Arthritis (RA)

Effects of Tofacitinib (CP-690,550) on Magnetic Resonance Imaging (MRI)- Assessed Joint Structure In Early Rheumatoid Arthritis (RA)

Other Conditions in Philadelphia