About Pricing FAQs Blog

Loading clinical trials...

Your health journey, clearly organized.

Find Clinical Trials →

Legal

Privacy Policy
Terms of Service

© 2026 Clareo Health. All rights reserved.

CHARITE™ vs. ALIF 5-Year Follow-up | Clinical Trials | Clareo Health

Back to clinical trial search

COMPLETEDNCT00215332

CHARITE™ vs. ALIF 5-Year Follow-up

To assess the clinical and radiographic outcomes through 5-years following treatment with CHARITÉ™ Artificial Disc vs. the BAK Cage for treatment of degenerative disc disease at one level (L4-S1).

Lead sponsor: DePuy Spine•10 U.S. locations•View source on ClinicalTrials.gov

Clareo plain-language summary

What this study is about

Generating AI summary...

Save this trial guide to your notes

Keep your clinical trial research organized — questions to ask, what to expect, and key details.

Sponsors

Lead Sponsor

DePuy Spine

This study is an extension out to 5 year follow-up of a randomized comparative IDE trial of the CHARITÉ™ Artificial Disc vs. ALIF with the BAK cage for treatment of degenerative disc disease. The original 2-year trial demonstrated non-inferiority of the CHARITÉ™ compared to ALIF. This extension will continue to follow-up the original outcome measures and will also examine adjacent segment progression.

Age

All ages

Sex

ALL

Healthy Volunteers

No

Inclusion Criteria

•Participated in either the training or randomized arm of the CHARITÉ Artificial Disc IDE study,
•Still have the original implant they received in their index surgery.

Exclusion Criteria

•None

Related studies

Comparison of Clinical Outcomes, Complications Rate and Treatment Costs of Mini-TLIF and MIDLIF in the Treatment of Discogenic Low Back Pain

NCT07127380 · Lower Back Pain Chronic, Lumbar Degenerative Disease, and more

RECRUITINGPhase 3

A Study to Evaluate the Effectiveness of IDCT (Intradiscal Cell Therapy) in Subjects With One Level, Symptomatic Mild to Moderate Lumbar Degenerative Disc Disease

NCT07254806 · Degenerative Disc Disease

"Lumbar Operatively Inserted PerQdisc Artificial Implant Following Nulcectomy" (LOPAIN2)

NCT05508360 · Degenerative Disc Disease, Chronic Low-back Pain

MagnetOs Flex Matrix Compared to Trinity Elite Mixed With Local Autograft in Patients Undergoing up to Four-level Instrumented Posterolateral Fusion

NCT05037968 · Degenerative Disc Disease, Spine Fusion, and more

RECRUITINGPhase 4

Regional Anesthesia in Minimally Invasive Lumbar Spine Surgery

NCT05029726 · Lumbar Spinal Stenosis, Lumbar Disc Herniation, and more

View all related studies →

Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: April 13, 2015Terms

Trial snapshot

StatusCOMPLETED

Phase—

Enrollment367

Start dateMar 2005

Last updatedApr 13, 2015

Condition

Degenerative Disc Disease

Locations shown

Charite Site 13

Los Angeles, California

Charite Site 06

Golden, Colorado

Charite Site 11

Chicago, Illinois

For caregivers

Use Clareo to keep notes, questions, trial details, and next steps organized before and after appointments.

Start free trial →

Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: April 13, 2015Data synced to Clareo: May 17, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

View ClinicalTrials.gov Terms and Conditions