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Clareo Health | Pancreatic Cancer Clinical Trials in Massachusetts | 382 Studies

Clinical Trials Pancreatic CancerMassachusetts

Pancreatic Cancer Clinical Trials in Massachusetts

Find 382 clinical trials for pancreatic cancer near Massachusetts. Connect with research centers in your area.

All Pancreatic Cancer trials nationwide All trials in Massachusetts

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 61-80 of 382 trials

CompletedStudy of Nanoliposomal Irinotecan (Nal-IRI)-Containing Regimens Versus Nab-paclitaxel Plus Gemcitabine in Patients With Previously Untreated, Metastatic Pancreatic AdenocarcinomaThis is an open-label, phase 2 non-comparative study to assess the safety, tolerability, and preliminary efficacy of nal-IRI in combination with other anticancer therapies in…NCT02551991·Mobile, Alabama and 35 others

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Data from ClinicalTrials.govTerms

TerminatedBinimetinib and Encorafenib for the Treatment of Pancreatic Cancer in Patients With a Somatic BRAF V600E MutationThis phase II trial studies the side effects and how well the combination of binimetinib and encorafenib work in treating patients with pancreatic cancer with a somatic BRAF V600E…NCT04390243·Phoenix, Arizona and 4 others

CompletedA Phase 1B Study of Canakinumab, Spartalizumab, Nab-paclitaxel, and Gemcitabine in Metastatic Pancreatic Cancer (PC) PatientsThis study combines canakinumab (ACZ885), a high-affinity human anti-interleukin-1β (IL-1β) monoclonal antibody (mAb), and spartalizumab (PDR001), a mAb directed against human…NCT04581343·Boston, Massachusetts and 1 other

UnknownThe Safety and Pharmacokinetics Preliminary Efficacy of IMP7068 in Patients With Advanced Solid TumorsA Phase 1 Dose Escalation and Expansion Study of IMP7068 Monotherapy in Advanced Solid TumorsNCT04768868·Atlanta, Georgia and 15 others

Active not recruitingNivolumab and Ipilimumab in Treating Patients With Rare TumorsThis phase II trial studies nivolumab and ipilimumab in treating patients with rare tumors.NCT02834013·Birmingham, Alabama and 1006 others

WithdrawnA Pilot Study of BXCL701 in Patients With Pancreatic CancerA study to assess the biochemical and immunomodulatory effects of BXCL701 in pancreatic cancer.NCT04123574·Boston, Massachusetts and 1 other

CompletedA Study to Collect Survival Data on Patients Previously Enrolled in Abraxane Pancreatic Cancer Study CA046.A study to collect survival data on patients previously enrolled in Abraxane pancreatic cancer study CA046.NCT02021500·Scottsdale, Arizona and 38 others

Approved for marketingExpanded Access for the Treatment of Cancers With Rearranged During Transfection (RET) ActivationExpanded access for participants with cancer with RET activation who are ineligible for an ongoing selpercatinib (also known as LOXO-292) clinical trial or have other…NCT03906331·Goodyear, Arizona and 63 others

TerminatedStudy of the CHK1 Inhibitor BBI-355, an ecDNA-directed Therapy (ecDTx), and the RNR Inhibitor BBI-825, in Subjects With Tumors With Oncogene AmplificationsBBI-355 is an oral, potent, selective checkpoint kinase 1 (or CHK1) small molecule inhibitor in development as an ecDNA (extrachromosomal DNA) directed therapy (ecDTx).NCT05827614·Los Angeles, California and 15 others

CompletedA Phase 1 Study of Pegilodecakin (LY3500518) in Participants With Advanced Solid TumorsThis is a first-in-human, open-label, dose escalation study to evaluate the safety and tolerability of pegilodecakin in participants with advanced solid tumors, dosed daily…NCT02009449·Los Angeles, California and 9 others

RecruitingSpevatamig (PT886) as Monotherapy or in Combination With Chemo and/or ICI, for the Treatment of Patients With Advanced Gastric, Gastroesophageal Junction, Pancreatic Ductal or Biliary Tract Carcinomas (the TWINPEAK Study)This is a first-in-human, Phase 1/2, open-label, dose escalation and dose expansion and combination study designed to evaluate the safety, tolerability, pharmacokinetics…NCT05482893·Duarte, California and 10 others

CompletedMasitinib in Combination With Gemcitabine for Treatment of Patients With Advanced/Metastatic Pancreatic CancerThe objective of this study is to compare the efficacy and safety of masitinib in combination with gemcitabine to placebo in combination with gemcitabine in patients with…NCT00789633·Norwich, Connecticut and 67 others

RecruitingA Study Evaluating FMC-376 in Participants With KRAS G12C Mutated Solid TumorsThe goal of this clinical trial is to evaluate FMC-376 in participants with advanced solid tumors with KRAS G12C mutations.NCT06244771·La Jolla, California and 25 others

CompletedStudy of XB002 in Subjects With Solid Tumors (JEWEL-101)This is a Phase 1, open-label, multicenter, dose-escalation and expansion study evaluating the safety, tolerability, PK, pharmacodynamics, and clinical antitumor activity of XB002…NCT04925284·Birmingham, Alabama and 94 others

CompletedAdjuvant Chemoradiotherapy and Interferon Alfa in Treating Patients With Resected Pancreatic CancerRATIONALE: Drugs used in chemotherapy, such as fluorouracil and cisplatin, work in different ways to stop tumor cells from dividing so they stop growing or die.NCT00059826·Gainesville, Florida and 13 others

CompletedRadiation w/FOLFIRINOX-Losartan for Pancreatic CancerThis is a Phase II clinical trial, which tests the safety and effectiveness of an investigational combination of drugs to learn whether the combination of drugs works in treating…NCT01821729·Boston, Massachusetts

CompletedStudy Evaluating Efficacy and Safety of FFX Versus Combination of CPI-613 With mFFX in Patients With Metastatic Adenocarcinoma of the PancreasA prospective, multicenter, open label, randomized phase III study to evaluate efficacy and safety of FFX versus CPI-613 + mFFX in patients with metastatic adenocarcinoma of the…NCT03504423·Gilbert, Arizona and 73 others

CompletedA Study of Botensilimab in Participants With Metastatic Pancreatic CancerThe goal of this clinical trial is to test if the addition of botensilimab to standard chemotherapy improves the efficacy compared to just chemotherapy alone in participants with…NCT05630183·Scottsdale, Arizona and 35 others

RecruitingStudy to Evaluate the Safety, Tolerability & Efficacy of TNG462 in Combination in PDAC & NSCLC PatientsTNG462-C102 is a Phase 1/2, open-label, multicenter study designed to determine the safety, tolerability, PK, PD, and preliminary antineoplastic activity of oral TNG462 in…NCT06922591·Scottsdale, Arizona and 17 others

CompletedA Study of LGK974 in Patients With Malignancies Dependent on Wnt LigandsThe primary purpose of this study was to find the recommended dose of LGK974 as a single agent and in combination with PDR001 that can be safely given to adult patients with…NCT01351103·Los Angeles, California and 19 others

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