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Improved Pre-Operative Staging of Pancreatic Cancer Using Superparamagnetic Iron Oxide Magnetic Resonance Imaging (SPIO MRI)
The purpose of this research study is to see if a specific kind of MRI, called Ultrasmall Superparamagnetic Iron Oxide Magnetic Resonance Imaging (USPIO MRI), which uses an FDA-approved therapeutic agent(Feraheme) to see if it is able to identify small and otherwise undetectable lymph node metastases in people who have pancreatic cancer and are scheduled for surgical resection.
* On the first day, study participants will undergo 2 MRI examinations. A scan will be done prior to administration of the contrast agent (Feraheme) and then a second scan immediately after administration. On the second day, study participants will be asked to return for a third MRI. * All MRI scans will be done at Massachusetts General Hospital.
Age
18 - No limit years
Sex
ALL
Healthy Volunteers
No
Massachusetts General Hospital
Boston, Massachusetts, United States
Start Date
July 1, 2008
Primary Completion Date
February 1, 2012
Completion Date
February 1, 2013
Last Updated
July 25, 2017
35
ACTUAL participants
Superparamagnetic Iron Oxide Magnetic Resonance Imaging
DRUG
Lead Sponsor
Massachusetts General Hospital
NCT04550494
NCT05053971
Data Source & Attribution
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