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Clareo Health | Melanoma Clinical Trials in Pittsburgh | 248 Studies

Clinical Trials MelanomaPittsburgh

Melanoma Clinical Trials in Pittsburgh

Find 248 clinical trials for melanoma near Pittsburgh, Pennsylvania. Connect with research centers in your area.

All Melanoma trials nationwide All trials in Pittsburgh

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

Who can join

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Showing 61-80 of 248 trials

TerminatedDabrafenib/Trametinib, BRAF or BRAF AND MEK Pre-op With BRAF and MEK Post-op, Phase IIB, Melanoma With Brain Mets,Biomarkers and MetabolitesThis is a global, multi-centre, open-label, study of GSK2118436 conducted in up to 30 evaluable subjects with resectable, BRAF V600E or V600K mutation-positive metastatic melanoma…NCT01978236·Pittsburgh, Pennsylvania and 2 others CompletedBiological Therapy in Treating Children With Refractory or Recurrent Neuroblastoma or Other TumorsRATIONALE: Biological therapies such as hu14.18-interleukin-2 fusion protein use different ways to stimulate the immune system and stop cancer cells from growing.NCT00003750·Little Rock, Arkansas and 58 others

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Data from ClinicalTrials.govTerms

CompletedA Study of XmAb®20717 in Subjects With Selected Advanced Solid TumorsThis is a Phase 1, multiple dose, ascending dose escalation study to define a MTD/RD and regimen of XmAb20717, to describe safety and tolerability, to assess PK and…NCT03517488·Los Angeles, California and 16 others

CompletedMulticentre, Dose Finding, Ph II,CP-4055 in Comb. With Sorafenib - Patients With Metastatic Malignant MelanomaPatients with metastatic malignant melanoma will receive CP-4055 200 mg/m2/day intravenously (IV) on Day 1-5 every four weeks and sorafenib 400 mg b.i.d. (twice daily) every day…NCT00498836·Pittsburgh, Pennsylvania and 5 others

CompletedPhotodynamic Therapy in Treating Patients With Stage III or Stage IV MelanomaRATIONALE: Photodynamic therapy uses light and drugs that make cancer cells more sensitive to light to kill tumor cells. Photodynamic therapy may be effective in treating melanoma.NCT00007969·Denver, Colorado and 5 others

RecruitingA Study to Investigate the Efficacy and Safety of an Infusion of IOV-4001 in Adult Participants With Unresectable or Metastatic Melanoma or Stage III or IV Non-small-cell Lung CancerThis is a study to investigate the efficacy and safety of an infusion of IOV-4001 in adult participants with unresectable or metastatic melanoma or advanced non-small-cell lung…NCT05361174·Los Angeles, California and 10 others

TerminatedTrial of Intratumoral Injections of TTI-621 in Subjects With Relapsed and Refractory Solid Tumors and Mycosis FungoidesThis is a multicenter, open-label, phase 1 study conducted to test intratumoral injections of TTI-621 in subjects that have relapsed and refractory percutaneously accessible solid…NCT02890368·Duarte, California and 6 others

Active not recruitingTacrolimus, Nivolumab, and Ipilimumab in Treating Kidney Transplant Recipients With Selected Unresectable or Metastatic CancersThis phase I trial studies how well tacrolimus, nivolumab, and ipilimumab work in treating kidney transplant recipients with cancer that cannot be removed by surgery…NCT03816332·Tampa, Florida and 6 others

CompletedVaccine Therapy in Treating Patients With Stage III or Stage IV MelanomaRATIONALE: Vaccines made from a person's dendritic cells mixed with tumor peptides and proteins may help the body build an effective immune response to kill tumor cells.NCT00390338·Pittsburgh, Pennsylvania and 1 other

CompletedA Study to Compare Nivolumab Drug Product Process D to Nivolumab Drug Product Process C in Participants With Stage IIIa/b/c/d or Stage IV Melanoma After Complete ResectionThe purpose of this study is to compare the drug levels, immunogenicity and safety of Nivolumab Process D to Nivolumab Process C after complete resection of stage IIIa/b/c/d or…NCT03980314·Hartford, Connecticut and 36 others

Active not recruitingA Trial to See if the Combination of Fianlimab With Cemiplimab Works Better Than Pembrolizumab for Preventing or Delaying Melanoma From Coming Back After it Has Been Removed With SurgeryThis study is researching an experimental drug called REGN3767, also known as fianlimab (R3767), when combined with another medication called cemiplimab (each individually called…NCT05608291·La Jolla, California and 210 others

CompletedA Study for the Treatment of Unresectable Stage III or Metastatic Stage IV MelanomaA study with YM155 for the treatment of unresectable stage III or metastatic stage IV melanoma.NCT00281541·Tuscon, Arizona and 8 others

TerminatedStudy of Nanrilkefusp Alfa Alone and With Pembrolizumab in Adult Patients With Advanced/Metastatic Solid TumorsA multicenter open-label phase 1/1b study to evaluate the safety and preliminary efficacy of nanrilkefusp alfa as monotherapy and in combination with pembrolizumab in patients…NCT04234113·New Haven, Connecticut and 11 others

CompletedVolociximab in Combination With DTIC in Patients With Metastatic Melanoma Not Previously Treated With ChemotherapyThis clinical trial is being conducted to determine tumor response and preliminary safety of a monoclonal antibody that specifically binds to a cell surface receptor (α5β1…NCT00099970·Birmingham, Alabama and 6 others

CompletedA Study to Compare BMS-936558 to the Physician's Choice of Either Dacarbazine or Carboplatin and Paclitaxel in Advanced Melanoma Patients That Have Progressed Following Anti-CTLA-4 Therapy (CheckMate 037)The purpose of the study is to estimate the response rate and compare overall survival of patients taking BMS-936558 to those taking study physician's choice of either Dacarbazine…NCT01721746·Phoenix, Arizona and 94 others

CompletedTreatment for Subjects With Unresectable Stage III or Stage IV MelanomaThis is a randomized, double blind, placebo controlled, multicenter, phase II study to compare the anti-tumor activity as measured by progression-free survival (PFS) and the…NCT00110994·Tucson, Arizona and 13 others

Active not recruitingSafety of SBRT With Anti-PD1 and Anti-IL-8 for the Treatment of Multiple Metastases in Advanced Solid Tumors and MelanomaNivolumab (and other agents affecting the anti-programmed death-1 \[anti-PD-1\] pathway) have demonstrated anti-tumor activity in multiple tumor types.NCT04572451·Chicago, Illinois and 1 other

Active not recruitingNeoadjuvant PD-1 Inhibitor Dostarlimab (TSR-042) vs. Combination of Tim-3 Inhibitor Cobolimab (TSR-022) and PD-1 Inhibitor Dostarlimab (TSR-042) in MelanomaThe purpose of this study is to test the effects of anti-PI-1 inhibitor (TSR-042) or anti-PD-1/anti-TIM-3 combination (TSR-042 / TSR-022) in patients with operable melanoma.NCT04139902·Washington D.C., District of Columbia and 4 others

Active not recruitingA First-in-human Study to Learn How Safe the Study Drug BAY2965501 is, Find the Best Dose (Single Drug & Combination), How it Affects the Body, What Maximum Amount Can be Given, How it Moves Into, Through and Out of the Body, How it Acts on Different Tumors in Participants With Advanced Solid TumorsResearchers are looking for a better way to treat people who have advanced solid tumors.NCT05614102·Denver, Colorado and 20 others

CompletedMDX-010 Antibody, MDX-1379 Melanoma Vaccine, or MDX-010/MDX-1379 Combination Treatment for Patients With Unresectable or Metastatic MelanomaThe purpose of this study is to determine the safety and efficacy of MDX-010 (ipilimumab, BMS-734016) (anti-CTLA4) in combination with MDX-1379 (gp100, BMS-734019) in patients…NCT00094653·Tucson, Arizona and 208 others

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