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Clareo Health | Melanoma Clinical Trials in Pittsburgh | 248 Studies

Clinical Trials MelanomaPittsburgh

Melanoma Clinical Trials in Pittsburgh

Find 248 clinical trials for melanoma near Pittsburgh, Pennsylvania. Connect with research centers in your area.

All Melanoma trials nationwide All trials in Pittsburgh

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Status

RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 41-60 of 248 trials

TerminatedA Study to Assess Adjuvant Immunotherapy With Nivolumab Plus Relatlimab Versus Nivolumab Alone After Complete Resection of Stage III-IV MelanomaThe purpose of this study is to assess nivolumab plus relatlimab fixed-dose combination (FDC) versus nivolumab alone in participants with completely resected stage III-IV melanoma.NCT05002569·Birmingham, Alabama and 183 others

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Data from ClinicalTrials.govTerms

RecruitingMC1R-targeted Alpha-particle Monotherapy and Combination Therapy Trial With Nivolumab in Adults With Advanced MelanomaIn this first-in human, phase I/IIa study, the safety and efficacy of \[212Pb\]VMT01, an alpha-particle emitting therapeutic agent targeted to melanocortin sub-type 1 receptor…NCT05655312·Orange, California and 12 others

CompletedSafety Study of Modified Vaccinia Virus to CancerThe purpose of this study is to determine the safety and maximum tolerated dose from injecting this vaccinia virus into tumors or infusion.NCT00574977·Pittsburgh, Pennsylvania

CompletedMelanoma Molecular Profiling AnalysisThere is a significant need to develop new and more effective ways to treat melanoma that will decrease patient morbidity and mortality.NCT00889980·Pittsburgh, Pennsylvania

RecruitingPatient Preference for Subcutaneous vs. Intravenous Immune TherapyThe study will evaluate patient and Health Care Professional- reported preference for Subcutaneous (SC) compared with IV nivolumab administration or similarly for SC compared with…NCT07223424·Pittsburgh, Pennsylvania

Active not recruitingTargeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas, or Multiple Myeloma (The MATCH Screening Trial)This phase II MATCH screening and multi-sub-trial studies how well treatment that is directed by genetic testing works in patients with solid tumors, lymphomas, or multiple…NCT02465060·Birmingham, Alabama and 1409 others

TerminatedA Phase 1a/1b Study of ACTM-838 in Patients With Advanced Solid TumorsThis is a first in human (FIH) 2-part study using ACTM-838 in patients with advanced solid tumors resistant to standard of care treatment.NCT06336148·Los Angeles, California and 4 others

CompletedStudy of VE800 and Nivolumab in Patients With Selected Types of Advanced or Metastatic CancerThis study evaluated the safety and efficacy of VE800 in combination with nivolumab in patients with selected types of advanced or metastatic cancerNCT04208958·Scottsdale, Arizona and 17 others

CompletedStudy of CP-675,206 in Refractory MelanomaCP-675,206 is a fully human monoclonal antibody (mAb). It binds to the CTLA4 molecule, which is expressed on the surface of activated T lymphocytes.NCT00254579·Scottsdale, Arizona and 64 others

CompletedPilot Study Evaluating Sulforaphane in Atypical Nevi-Precursor LesionsThis is a pilot study to see if oral administration of freeze dried, powdered broccoli sprouts have any effect on whether moles end up becoming melanoma.NCT01568996·Pittsburgh, Pennsylvania

RecruitingA First-In Human (FIH) Study to Find Out How Well REGN10597 Medicine Given Alone or in Combination With Cemiplimab Works in Adult Participants Who Have Cancer With Tumors That Have Spread in Their BodyThis study is researching an experimental drug called REGN10597 alone or in combination with another drug called cemiplimab (called "study drug(s)").NCT06413680·Los Angeles, California and 10 others

CompletedStudy of TLR9 Agonist Vidutolimod (CMP-001) in Combination With Nivolumab vs. NivolumabThe main goal of this research study is to determine how nivolumab and nivolumab/Vidutolimod (CMP-001) combination affect the likelihood of destroying melanoma involving lymph…NCT04401995·Pittsburgh, Pennsylvania

Active not recruitingVeliparib, Paclitaxel, and Carboplatin in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery and Liver or Kidney DysfunctionThis phase I trial studies the side effects and the best dose of veliparib when given together with paclitaxel and carboplatin in treating patients with solid tumors that are…NCT01366144·Duarte, California and 16 others

CompletedLUMINOS-102: Lerapolturev With or Without Immune Checkpoint Blockade in Advanced PD-1 Refractory MelanomaA Phase 2 study to investigate the efficacy and safety of lerapolturev alone or in combination with a programmed death receptor-1 (anti-PD-1) inhibitor.NCT04577807·Scottsdale, Arizona and 11 others

Active not recruitingA Trial to Learn if Fianlimab and Cemiplimab Are Safe and Work Better Than Anti-PD1 Alone in Adult Participants With Resectable Stage 3 or 4 MelanomaThis study is researching an experimental drug called REGN3767, also known as fianlimab (R3767), when combined with another medication called cemiplimab (each individually called…NCT06190951·La Jolla, California and 103 others

CompletedA Study of Vemurafenib in Previously Treated Patients With Metastatic MelanomaThis open-label single arm study will assess the efficacy, safety and tolerability of Vemurafenib in previously treated patients with metastatic melanoma.NCT00949702·Los Angeles, California and 14 others

CompletedNeoadjuvant Combination Therapy With Ipilimumab and HighDose IFN-α2b for MelanomaThe purpose of this study is to evaluate the safety and potential effectiveness of a new treatment for advanced and recurrent melanoma involving the combination of Ipilimumab and…NCT01608594·Pittsburgh, Pennsylvania

CompletedTreatment of Advanced Melanoma With MK-3475 and PeginterferonThis study is to test how safe it is to give the combination of PEG IFN-α2b (SYLATRON) and MK-3475, an investigational drug, to patients with advanced melanoma.NCT02112032·Pittsburgh, Pennsylvania

CompletedCP-675,206 In Patients With Advanced MelanomaThe purpose of this study is to assess the efficacy, safety, and tolerability of monoclonal antibody therapy using 2 regimens for the treatment of advanced melanomaNCT00086489·Los Angeles, California and 8 others

TerminatedA Phase 1/2 Randomized, Blinded, Placebo Controlled Study of Ipilimumab in Combination With Epacadostat or Placebo in Subjects With Unresectable or Metastatic MelanomaThe study design included an open-label, dose escalation phase followed by a blinded, randomized phase, which combined epacadostat (an oral IDO1 inhibitor) with an approved…NCT01604889·Los Angeles, California and 6 others

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