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Clareo Health | Melanoma Clinical Trials in Pittsburgh | 249 Studies

Clinical Trials MelanomaPittsburgh

Melanoma Clinical Trials in Pittsburgh

Find 249 clinical trials for melanoma near Pittsburgh, Pennsylvania. Connect with research centers in your area.

All Melanoma trials nationwide All trials in Pittsburgh

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Status

RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4Not applicable

Who can join

Healthy volunteers too

Showing 81-100 of 249 trials

CompletedIpilimumab With or Without High-Dose Recombinant Interferon Alfa-2b in Treating Patients With Stage III-IV Melanoma That Cannot Be Removed by SurgeryThis randomized phase II trial studies how well ipilimumab with or without high-dose recombinant interferon alpha-2b works in treating patients with stage III-IV melanoma that…NCT01708941·Birmingham, Alabama and 275 others

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Data from ClinicalTrials.govTerms

CompletedCP-675,206 Versus Either Dacarbazine Or Temozolomide In Patients Without Prior TherapyThis is a Phase 3, multi-national, open-label, 2-arm randomized study in patients with surgically incurable metastatic melanoma who have received no prior chemotherapy, or…NCT00257205·Huntsville, Alabama and 142 others

Active not recruitingA Clinical Study of Intismeran Autogene (V940) Plus Pembrolizumab in People With High-Risk Melanoma (V940-001)The purpose of this study is to learn if intismeran autogene which is an individualized neoantigen therapy (INT; formerly, called messenger ribonucleic acid \[mRNA\]-4157) with…NCT05933577·Springdale, Arkansas and 164 others

Active not recruitingA First-in-human Study to Learn How Safe the Study Drug BAY2965501 is, Find the Best Dose (Single Drug & Combination), How it Affects the Body, What Maximum Amount Can be Given, How it Moves Into, Through and Out of the Body, How it Acts on Different Tumors in Participants With Advanced Solid TumorsResearchers are looking for a better way to treat people who have advanced solid tumors.NCT05614102·Denver, Colorado and 20 others

RecruitingImmunotherapy in Combination With Prednisone and Sirolimus for Kidney Transplant Recipients With Unresectable or Metastatic Skin CancerThis phase II trial tests the combination of nivolumab and ipilimumab with sirolimus and prednisone for the treatment of skin (cutaneous) cancer that cannot be removed by surgery…NCT05896839·La Jolla, California and 25 others

TerminatedCMP-001 in Combination With Nivolumab Compared to Nivolumab Monotherapy in Subjects With Advanced MelanomaCMP-001-011 is a Phase 2/3 study of CMP-001 intratumoral (IT) and nivolumab intravenous (IV) compared to nivolumab monotherapy administered to participants with unresectable or…NCT04695977·Phoenix, Arizona and 19 others

CompletedAn Investigational Immuno-therapy Study to Evaluate Safety and Effectiveness in Patients With Melanoma That Has Spread to the Brain, Treated With Nivolumab in Combination With Ipilimumab, Followed by Nivolumab by ItselfThis is a study of Nivolumab combined with Ipilimumab followed by Nivolumab by itself for the treatment of patients with Melanoma that has spread to the brain.NCT02320058·Duarte, California and 35 others

CompletedImproving Adherence to Oral Cancer Agents and Self Care of Symptoms Using an IVRImproving Adherence to Oral Cancer Agents and Self Care of Symptoms Using an IVR The goals of this study are to improve adherence to oral chemotherapeutic medications and…NCT02043184·New Haven, Connecticut and 7 others

Active not recruitingTesting Longer Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With Cancer That Has Spread to the BrainThis phase III trial compares the effectiveness of fractionated stereotactic radiosurgery (FSRS) to usual care stereotactic radiosurgery (SRS) in treating patients with cancer…NCT06500455·Tucson, Arizona and 269 others

Active not recruitingDabrafenib and Trametinib Followed by Ipilimumab and Nivolumab or Ipilimumab and Nivolumab Followed by Dabrafenib and Trametinib in Treating Patients With Stage III-IV BRAFV600 MelanomaThis phase III trial studies how well initial treatment with ipilimumab and nivolumab followed by dabrafenib and trametinib works and compares it to initial treatment with…NCT02224781·Birmingham, Alabama and 837 others

Active not recruitingTesting the Addition of the Anti-cancer Drug, Tazemetostat, to the Usual Treatment (Dabrafenib and Trametinib) for Metastatic Melanoma That Has Progressed on the Usual TreatmentThis phase I/II trial investigates the best dose, possible benefits and/or side effects of tazemetostat in combination with dabrafenib and trametinib in treating patients with…NCT04557956·Aventura, Florida and 16 others

CompletedPhase 1/2 Study Exploring the Safety, Tolerability, and Efficacy of INCAGN01876 Combined With Immune Therapies in Advanced or Metastatic MalignanciesThe purpose of this study is to determine the safety, tolerability, and efficacy of INCAGN01876 when given in combination with immune therapies in subjects with advanced or…NCT03126110·Los Angeles, California and 37 others

CompletedMulticentre, Dose Finding, Ph II,CP-4055 in Comb. With Sorafenib - Patients With Metastatic Malignant MelanomaPatients with metastatic malignant melanoma will receive CP-4055 200 mg/m2/day intravenously (IV) on Day 1-5 every four weeks and sorafenib 400 mg b.i.d. (twice daily) every day…NCT00498836·Pittsburgh, Pennsylvania and 5 others

Active not recruitingStudy of ARRY-614 Plus Either Nivolumab or Nivolumab+IpilimumabIn this study, the Phase Ib portion aims to establish safety and tolerability of ARRY-614 with either nivolumab or ipilimumab and to determine a recommended phase II dose of…NCT04074967·Pittsburgh, Pennsylvania

CompletedSafety Study of Enoblituzumab (MGA271) in Combination With Pembrolizumab or MGA012 in Refractory CancerThe purpose of this study is to evaluate the safety of enoblituzumab (MGA271) in combination with Keytruda (pembrolizumab) when given to patients with B7-H3-expressing melanoma…NCT02475213·Scottsdale, Arizona and 19 others

RecruitingRP1 in Primary Melanoma to Reduce the Risk of Sentinel Lymph Node MetastasisThis early-phase study will examine Vusolimogene Oderparepvec, a genetically modified oncolytic viral strain of the herpes simplex type 1 (HSV-1) virus, with potential oncolytic…NCT06216938·Pittsburgh, Pennsylvania

Active not recruitingTesting the Combination of the Anti-cancer Drugs XL184 (Cabozantinib) and Nivolumab in Patients With Advanced Cancer and HIVThis phase I trial investigates the side effects of cabozantinib and nivolumab in treating patients with cancer that may have spread from where it first started to nearby tissue…NCT04514484·Chicago, Illinois and 2 others

Active not recruitingA Study of Safety and Efficacy of KFA115 Alone and in Combo With Pembrolizumab in Patients With Select Advanced CancersThe purpose of this study is to characterize the safety and tolerability of KFA115 and KFA115 in combination with pembrolizumab in patients with select advanced cancers, and to…NCT05544929·Boston, Massachusetts and 17 others

No longer availableExpanded Access Study of Melphalan With Delcath CS-PHP System in Patients With Ocular/Cutaneous Melanoma Mets to LiverThe safety and efficacy of CS-PHP-melphalan has been evaluated in a phase 3 trial conducted in the same patient population as well as using the same melphalan dosing as proposed…NCT01728051·Santa Monica, California and 5 others

CompletedSafety of TKI258 in Advanced/Metastatic Melanoma SubjectsThis study is an open-label, dose-escalating study to delineate the safety, pharmacokinetics (PK), and pharmacodynamics (PD) of TKI258.NCT00303251·Louisville, Kentucky and 2 others

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