Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Point Therapeutics
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Histologically or cytologically confirmed melanoma that is metastatic (unresectable Stage IV per AJCC 2002)
Patients with measurable disease defined as at least one measurable index lesion with clearly defined margins
ECOG Performance Status of 0, 1, or 2
Expected survival ≥12 weeks
Written informed consent
You may not be if
More than 1 prior chemotherapy or biotherapy regimen for Stage IV melanoma
Radiation therapy to \>50% of the bone marrow. Patients must not have had prior radiotherapy to index lesions unless they have clearly progressive disease in this site or there is measurable disease outside the area of prior radiation.
Clinically significant laboratory abnormalities
CNS metastases
Any malignancy within the 5 years immediately prior to the first dose of study medication with the exception of basal cell or non-metastatic squamous cell carcinoma of the skin, and carcinoma in-situ of the cervix
The need for chronic (i.e., \>7 days) oral or intravenous corticosteroid therapy
Any comorbidity or condition which, in the opinion of the investigator, may interfere with the assessments and procedures of this protocol
Patients who are within 30 days of chemotherapy, radiation therapy, immunotherapy, or other investigational medication for melanoma. Patients must have recovered from all of the side effects of treatment in order to be enrolled.
