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Clareo Health | Melanoma Clinical Trials in Pittsburgh | 249 Studies

Clinical Trials MelanomaPittsburgh

Melanoma Clinical Trials in Pittsburgh

Find 249 clinical trials for melanoma near Pittsburgh, Pennsylvania. Connect with research centers in your area.

All Melanoma trials nationwide All trials in Pittsburgh

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Status

RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4Not applicable

Who can join

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Showing 21-40 of 249 trials

CompletedPhase 1 Study of GRN-1201 in HLA-A*02 Subjects With Resected MelanomaThis is a study of an investigational cancer vaccine called GRN-1201. Treatment with the GRN-1201 vaccine is a type of immunotherapy.NCT02696356·Cincinnati, Ohio and 3 others CompletedA Study of Lymphoseek® as a Lymphoid Tissue Targeting Agent in Pediatric Patients With Melanoma, Rhabdomyosarcoma, or Other Solid Tumors Who Are Undergoing Lymph Node MappingOpen label, non-randomized, multi-center, within-subject comparative study to evaluate the tolerability and the diagnostic utility of Lymphoseek with optional comparison to VBD in…NCT02509598·Jacksonville, Florida and 5 others CompletedVolociximab in Combination With DTIC in Patients With Metastatic Melanoma Not Previously Treated With ChemotherapyThis clinical trial is being conducted to determine tumor response and preliminary safety of a monoclonal antibody that specifically binds to a cell surface receptor (α5β1…NCT00099970·Birmingham, Alabama and 6 others

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Data from ClinicalTrials.govTerms

CompletedA Study of Tasisulam in Treating Participants With Malignant MelanomaThe primary purpose of this study is to determine the objective response rate (complete and partial response) for participants who receive tasisulam after one prior systemic…NCT00383292·Los Angeles, California and 12 others

CompletedSafety Study of Modified Vaccinia Virus to CancerThe purpose of this study is to determine the safety and maximum tolerated dose from injecting this vaccinia virus into tumors or infusion.NCT00574977·Pittsburgh, Pennsylvania

TerminatedA Phase III Study to Test the Benefit of a New Kind of Anti-cancer Treatment in Patients With Melanoma, After Surgical Removal of Their TumorThe purpose of this clinical trial is to evaluate the benefit of the immunotherapeutic product GSK 2132231A in preventing disease relapse when given to melanoma patients, after…NCT00796445·Birmingham, Alabama and 256 others

Active not recruitingTesting Two Different Treatment Schedules of Dabrafenib and Trametinib for Skin Cancer Which Has SpreadThis phase II trial compares the effect of dabrafenib and trametinib given continuously to given with a break in treatment (intermittent) in treating patients with stage III-IV…NCT02196181·Birmingham, Alabama and 751 others

TerminatedGamma-Secretase/Notch Signalling Pathway Inhibitor RO4929097 in Treating Patients With Stage IV MelanomaThis phase II trial is studying how well gamma-secretase/Notch signalling pathway inhibitor RO4929097 works in treating patients with stage IV melanoma.NCT01120275·Mobile, Alabama and 177 others

CompletedVaccine Therapy Using Melanoma Peptides for Cytotoxic T Cells and Helper T Cells in Treating Patients With Metastatic MelanomaRATIONALE: Vaccines made from peptides may make the body build an immune response to kill tumor cells.NCT00071981·Palo Alto, California and 64 others

CompletedNeoadjuvant Combination Biotherapy With Pembrolizumab and High Dose IFN-alfa2bThis study plans to to estimate the safety profile of the combination biotherapy regimen consisting of standard-dose interferon alpha-2b (HDI) and anti-PD1 monoclonal antibody…NCT02339324·Buffalo, New York and 1 other

CompletedStudy of CP-675,206 in Refractory MelanomaCP-675,206 is a fully human monoclonal antibody (mAb). It binds to the CTLA4 molecule, which is expressed on the surface of activated T lymphocytes.NCT00254579·Scottsdale, Arizona and 64 others

Active not recruitingTacrolimus, Nivolumab, and Ipilimumab in Treating Kidney Transplant Recipients With Selected Unresectable or Metastatic CancersThis phase I trial studies how well tacrolimus, nivolumab, and ipilimumab work in treating kidney transplant recipients with cancer that cannot be removed by surgery…NCT03816332·Tampa, Florida and 6 others

TerminatedA Study Evaluating the Safety and Antitumor Activity of IPI-504, in Patients With Metastatic MelanomaTo evaluate the antitumor activity of IPI-504 in patients with metastatic melanoma.NCT00627419·Tuscon, Arizona and 16 others

RecruitingSUPRAME-ACTengine® IMA203 vs. Investigator's Choice of Treatment in Previously Treated, Unresectable or Metastatic Cutaneous MelanomaThis clinical trial is a prospective, multicenter, open-label, randomized, actively controlled, parallel-group Phase 3 clinical trial to evaluate the efficacy, safety and…NCT06743126·Phoenix, Arizona and 70 others

TerminatedTovorafenib (DAY101) Monotherapy for Patients With Melanoma and Other Solid TumorsThis is a Phase 2, multi-center, open-label to evaluate the efficacy and safety of tovorafenib (DAY101) in participants ≥12 years of age with recurrent or progressive melanoma or…NCT04985604·Los Angeles, California and 19 others

CompletedSafety, Tolerability and Efficacy Study of the Monoclonal Antibody, CT-011, in Patients With Metastatic MelanomaThe purpose of this research study is to see if the study drug, CT-011, is safe to give and if it helps people with melanoma that has spread to other areas of their body.NCT01435369·New Haven, Connecticut and 17 others

Active not recruitingEffectiveness Study of Nivolumab Compared to Placebo in Prevention of Recurrent Melanoma After Complete Resection of Stage IIB/C MelanomaThe purpose of this study is to determine the effectiveness of nivolumab adjuvant immunotherapy compared to placebo in adults and pediatric participants after complete resection…NCT04099251·Birmingham, Alabama and 129 others

CompletedInterferon Alfa-2b With or Without Radiation Therapy in Treating Patients With Melanoma That Has Metastasized to Lymph Nodes in the Neck, Under the Arm, or in the GroinRATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. Interferon alfa-2b may interfere with the growth of cancer cells.NCT00003444·Atlanta, Georgia and 22 others

CompletedTreatment of Advanced Melanoma With MK-3475 and PeginterferonThis study is to test how safe it is to give the combination of PEG IFN-α2b (SYLATRON) and MK-3475, an investigational drug, to patients with advanced melanoma.NCT02112032·Pittsburgh, Pennsylvania

TerminatedStudy Of Zelboraf (Vemurafenib) in Patients With Locally-Advanced, Unresectable, Stage IIIc Or Metastatic Melanoma and Activating Exon 15 BRAF Mutations Other Than V600EThis is an open-label, multicenter, single-agent, phase II study of continuous oral Zelboraf (vemurafenib) in participants with locally-advanced, unresectable, stage IIIc or…NCT01586195·Tucson, Arizona and 14 others

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