Finding studies
Finding studies
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Lead
Yana Najjar
With
This single-arm Phase II study will evaluate the safety and efficacy of neoadjuvant RP2 in combination with nivolumab in adults with resectable advanced melanoma. Participants will receive RP2 and nivolumab prior to surgery, followed by adjuvant nivolumab after surgery. The study will assess pathologic response at surgery, treatment-related toxicity, tumor response, recurrence-free survival, and overall survival. Exploratory analyses will evaluate changes in immune and tumor biomarkers associated with treatment response.
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted