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Clareo Health | Melanoma Clinical Trials in Massachusetts | 361 Studies

Clinical Trials MelanomaMassachusetts

Melanoma Clinical Trials in Massachusetts

Find 361 clinical trials for melanoma near Massachusetts. Connect with research centers in your area.

All Melanoma trials nationwide All trials in Massachusetts

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 161-180 of 361 trials

RecruitingSafety and Efficacy of NEO212 in Patients With Astrocytoma IDH-mutant, Glioblastoma IDH-wildtype or Brain MetastasisThis multi-site, Phase 1/2 clinical trial is an open-label study to identify the safety, pharmacokinetics, and efficacy of a repeated dose regimen of NEO212 alone for the…NCT06047379·Beverly Hills, California and 7 others Active not recruitingA Phase 1/2a Study of IMM-1-104 in Participants With Advanced or Metastatic Solid TumorsThis is an open-label, dose-exploration and expansion study to determine the safety, tolerability, pharmacokinetics, pharmacodynamics, and preliminary anti-tumor activity of…NCT05585320·Scottsdale, Arizona and 19 others

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Data from ClinicalTrials.govTerms

RecruitingInAdvance: Surveillance, Prevention, and Interception in a Population at Risk for CancerThis research study is creating a way to collect and store specimens and information from participants who may be at an increased risk of developing cancer, or has been diagnosed…NCT05463796·Boston, Massachusetts

TerminatedStudy of INBRX-105 and INBRX-105 With Pembrolizumab in Patients With Solid Tumors Including Head and Neck CancerThis is a first-in-human, open-label, nonrandomized, four-part trial to determine the safety profile and identify the maximum tolerated dose (MTD) and/or recommended Phase 2 dose…NCT03809624·Scottsdale, Arizona and 22 others

TerminatedHigh-Risk Skin Cancers With Atezolizumab Plus NT-I7The purpose of this study is to test whether the addition of NT-I7 to atezolizumab provides clinically meaningful outcomes for patients with anti-PD-1/PD-L1 naive or…NCT03901573·Duarte, California and 7 others

CompletedA Study of LY3214996 Administered Alone or in Combination With Other Agents in Participants With Advanced/Metastatic CancerThe purpose of this study is to determine the safety of an extracellular signal regulated kinase (ERK1/2) inhibitor LY3214996 administered alone or in combination with other…NCT02857270·Washington D.C., District of Columbia and 12 others

Active not recruitingPhysician/Patient Choice of Either High-Dose Recombinant Interferon Alfa-2B or Ipilimumab, Versus Pembrolizumab in Treating Patients With Stage III-IV High Risk Melanoma That Has Been Removed by SurgeryThis randomized phase III trial studies how well pembrolizumab works compared with the current standard of care, physician/patient choice of either high-dose recombinant…NCT02506153·Birmingham, Alabama and 575 others

Active not recruitingQUILT-3.055: A Study of Combination Immunotherapies in Patients Who Have Previously Received Treatment With Immune Checkpoint InhibitorsQUILT-3.055 is a Phase 2b, open-label, multicohort study investigating combination immunotherapies in patients with advanced solid tumors who have previously been treated with…NCT03228667·Anchorage, Alaska and 34 others

TerminatedCabozantinib-S-Malate and Vemurafenib in Treating Patients With Solid Tumors or Melanoma That is Metastatic or That Cannot Be Removed By SurgeryThis phase I trial studies the side effects and best dose of cabozantinib-s-malate when given together with vemurafenib in treating patients with solid tumors or melanoma that is…NCT01835184·Atlanta, Georgia and 2 others

Active not recruitingHigh-Dose Interferon Alfa in Treating Patients With Stage II or Stage III MelanomaRATIONALE: Interferon alfa may interfere with the growth of cancer cells.NCT00003641·Birmingham, Alabama and 532 others

Active not recruitingSX-682 Treatment in Subjects With Metastatic Melanoma Concurrently Treated With PembrolizumabCancers attract myeloid-derived suppressor cells (MDSCs) that prevent our own immune responses from destroying the cancer.NCT03161431·Miami, Florida and 5 others

TerminatedS9903: Whole Brain Radiotherapy Followed By Stereotactic Radiosurgery for Limited Malignant Melanoma Brain MetastasesRATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. Stereotactic radiosurgery may kill more tumor cells.NCT00003911·Mobile, Alabama and 85 others

Active not recruitingA Phase II Trial of PD-L1 Therapy Combined With Anti-VEGF Therapy in Unresectable or Metastatic MelanomaThis research study is studying a combination of two drugs that change the immune system and tumor as a possible treatment for metastatic or unresectable stage III or IV cutaneous…NCT04356729·Boston, Massachusetts and 2 others

CompletedA Safety, Tolerability and PK Study of DCC-2618 in Patients With Advanced MalignanciesThis is a Phase 1, open-label, first-in-human (FIH) dose-escalation study designed to evaluate the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD), and…NCT02571036·Scottsdale, Arizona and 25 others

UnknownStudy of NGM707 As Monotherapy and in Combination with Pembrolizumab in Advanced or Metastatic Solid Tumor MalignanciesStudy of NGM707 as Monotherapy and in Combination with Pembrolizumab in Advanced or Metastatic Solid Tumor MalignanciesNCT04913337·Los Angeles, California and 26 others

RecruitingSUPRAME-ACTengine® IMA203 vs. Investigator's Choice of Treatment in Previously Treated, Unresectable or Metastatic Cutaneous MelanomaThis clinical trial is a prospective, multicenter, open-label, randomized, actively controlled, parallel-group Phase 3 clinical trial to evaluate the efficacy, safety and…NCT06743126·Phoenix, Arizona and 70 others

TerminatedITIL-168 in Advanced MelanomaDELTA-1 is a phase 2 clinical trial to evaluate the efficacy and safety of ITIL-168 in adult subjects with advanced melanoma who have previously been treated with a PD-1 inhibitor.NCT05050006·La Jolla, California and 21 others

CompletedStudy of Nivolumab Given Sequentially With Ipilimumab in Subjects With Advanced or Metastatic Melanoma (CheckMate 064)The purpose of this study is to evaluate the safety and efficacy of a sequential combination therapy of Nivolumab and IpilimumabNCT01783938·Tampa, Florida and 10 others

UnknownGI Complications in Cancer Immunotherapy PatientsThe purpose of this study is to establish a prospective observational cohort of cancer immunotherapy patients with GI side effects in order to identify biomarkers that predict GI…NCT02784366·Boston, Massachusetts

CompletedAn Investigational Immuno-therapy Study to Evaluate Safety and Effectiveness in Patients With Melanoma That Has Spread to the Brain, Treated With Nivolumab in Combination With Ipilimumab, Followed by Nivolumab by ItselfThis is a study of Nivolumab combined with Ipilimumab followed by Nivolumab by itself for the treatment of patients with Melanoma that has spread to the brain.NCT02320058·Duarte, California and 35 others

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