Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Genta Incorporated
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Histologically confirmed diagnosis of melanoma
Progressive disease that is not surgically resectable, or metastatic Stage IV
Low-normal LDH, defined as ≤ 0.8 times the upper limit of normal
No prior chemotherapy
Measurable disease
ECOG performance status ≤ 1
At least 4 weeks and recovery from effects of major prior surgery or other therapy, including immunotherapy, radiation therapy, or cytokine, biologic or vaccine therapy
Prior immunotherapy allowed
Adequate organ function
You may not be if
Prior cytotoxic chemotherapy, including regional perfusion, or prior Genasense treatment
Primary ocular or mucosal melanoma
Bone-only metastatic disease
History or presence of brain metastasis or leptomeningeal disease
Significant medical disease other than cancer
Organ allograft
Clareo Health | Trial of Dacarbazine With or Without Genasense in Advanced Melanoma
