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Clareo Health | Melanoma Clinical Trials in Massachusetts | 363 Studies

Clinical Trials MelanomaMassachusetts

Melanoma Clinical Trials in Massachusetts

Find 363 clinical trials for melanoma near Massachusetts. Connect with research centers in your area.

All Melanoma trials nationwide All trials in Massachusetts

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Status

RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4Not applicable

Who can join

Healthy volunteers too

Showing 181-200 of 363 trials

CompletedA Study of the Effects of ALKS 4230 (Nemvaleukin Alfa) on Subjects With Solid TumorsTo better understand the safety and tolerability of ALKS 4230 in humansNCT02799095·Denver, Colorado and 30 others Active not recruitingStudy of Safety and Efficacy of DKY709 Alone or in Combination With PDR001 in Patients With Advanced Solid Tumors.This is a phase I/Ib, open label study.NCT03891953·Boston, Massachusetts and 8 others

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Data from ClinicalTrials.govTerms

CompletedA Study of BMS-986253 in Combination With Nivolumab or Nivolumab Plus Ipilimumab in Advanced CancersThe purpose of this study is to investigate experimental medication BMS-986253 in combination with Nivolumab or Nivolumab plus Ipilimumab in participants with advanced cancers.NCT03400332·Springdale, Arkansas and 71 others

TerminatedIpilimumab With or Without Dabrafenib, Trametinib, and/or Nivolumab in Treating Patients With Melanoma That Is Metastatic or Cannot Be Removed by SurgeryThis randomized phase I trial studies the side effects and best way to give ipilimumab with or without dabrafenib, trametinib and/or nivolumab in treating patients with melanoma…NCT01940809·Boston, Massachusetts and 1 other

TerminatedThe Effects of Vemurafenib + Cobimetinib on Immunity in Patients With MelanomaThis study is for patients with malignant melanoma which has spread beyond the local area and cannot be surgically removed, and who have melanoma tumors that are accessible for…NCT01813214·Washington D.C., District of Columbia and 3 others

TerminatedPhase I-Ib/II Study of MBG453 as Single Agent and in Combination With PDR001 in Patients With Advanced MalignanciesThe purpose of this first-in-human study of MBG453 was to characterize the safety, tolerability, pharmacokinetics, pharmacodynamics and anti-tumor activity of MBG453 administered…NCT02608268·Baltimore, Maryland and 13 others

CompletedIpilimumab With or Without Bevacizumab in Treating Patients With Stage III-IV Melanoma That Cannot Be Removed by SurgeryThis randomized phase II trial studies how well ipilimumab with or without bevacizumab works in treating patients with stage III-IV melanoma that cannot be removed by surgery.NCT01950390·Birmingham, Alabama and 481 others

Active not recruitingA Study of TSR-022 in Participants With Advanced Solid Tumors (AMBER)This is a first-in-human study evaluating the anti-T cell immunoglobulin and mucin containing protein-3 (TIM-3) antibody TSR-022.NCT02817633·Goodyear, Arizona and 88 others

Active not recruitingStudy of LY3410738 Administered to Patients With Advanced Solid Tumors With IDH1 or IDH2 MutationsThis is an open-label, multicenter Phase 1 study to evaluate safety, tolerability and preliminary efficacy of oral LY3410738 in patients with isocitrate dehydrogenase 1 (IDH1)…NCT04521686·Phoenix, Arizona and 32 others

CompletedSargramostim, Vaccine Therapy, or Sargramostim and Vaccine Therapy in Preventing Disease Recurrence in Patients With Melanoma That Has Been Removed By SurgeryThis randomized phase III trial studies sargramostim or vaccine therapy alone to see how well they work compared to sargramostim and vaccine therapy together in preventing disease…NCT01989572·Birmingham, Alabama and 147 others

TerminatedPembrolizumab With Talimogene Laherparepvec or Placebo in Unresected MelanomaThe primary objectives of the Phase 1b part of the study are to evaluate the safety, as assessed by incidence of dose limiting toxicity (DLT), of talimogene laherparepvec in…NCT02263508·Birmingham, Alabama and 160 others

CompletedStudy of Nivolumab Given Sequentially With Ipilimumab in Subjects With Advanced or Metastatic Melanoma (CheckMate 064)The purpose of this study is to evaluate the safety and efficacy of a sequential combination therapy of Nivolumab and IpilimumabNCT01783938·Tampa, Florida and 10 others

UnknownVaccine Therapy in Treating Patients With Stage III or Stage IV MelanomaRATIONALE: Vaccines made from a patient's dendritic cells may make the body build an immune response to kill tumor cells.NCT00085397·Boston, Massachusetts and 2 others

CompletedStudy in Patients With Unresectable And Metastatic Melanoma: The Optimize StudyThis study evaluates the different patterns of care for patients who have unresectable or metastatic melanoma.NCT02780089·Muscle Shoals, Alabama and 65 others

CompletedStudy of CP-675,206 in Refractory MelanomaCP-675,206 is a fully human monoclonal antibody (mAb). It binds to the CTLA4 molecule, which is expressed on the surface of activated T lymphocytes.NCT00254579·Scottsdale, Arizona and 64 others

TerminatedPROCLAIM: CX-072-002: Study of PD-L1 Probody Therapeutic CX-072 in Combination With Other Anticancer Therapy in Adults With Solid TumorsTo obtain evidence of antitumor effect of CX-072 in combination with anticancer therapy in adult patients with solid tumor based upon overall response rate by Response Evaluation…NCT03993379·Duarte, California and 26 others

CompletedStudy of Cabozantinib (XL184) in Adults With Advanced MalignanciesThis is a Phase 2 study to evaluate the efficacy and safety of cabozantinib (XL184) in subjects with selected advanced tumor types.NCT00940225·Scottsdale, Arizona and 46 others

Active not recruitingTesting the Addition of Navitoclax to the Combination of Dabrafenib and Trametinib in People Who Have BRAF Mutant MelanomaThis phase I/II trial studies the side effects and best dose of dabrafenib, trametinib, and navitoclax and to see how well they work in treating patients with BRAF mutant melanoma…NCT01989585·Phoenix, Arizona and 48 others

CompletedSafety, Tolerability and Efficacy Study of the Monoclonal Antibody, CT-011, in Patients With Metastatic MelanomaThe purpose of this research study is to see if the study drug, CT-011, is safe to give and if it helps people with melanoma that has spread to other areas of their body.NCT01435369·New Haven, Connecticut and 17 others

Active not recruitingNeoantigen Vaccine Plus Locally Administered Ipilimumab and Systemic Nivolumab in Advanced MelanomaThis research study is investigating a new type of personalized neoantigen vaccine, NeoVax, plus Montanide® in combination with Ipilimumab (Yervoy™) and Nivolumab (Opdivo®) as a…NCT03929029·Boston, Massachusetts

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