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Clareo Health | Melanoma Clinical Trials in Massachusetts | 363 Studies

Clinical Trials MelanomaMassachusetts

Melanoma Clinical Trials in Massachusetts

Find 363 clinical trials for melanoma near Massachusetts. Connect with research centers in your area.

All Melanoma trials nationwide All trials in Massachusetts

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Status

RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4Not applicable

Who can join

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Showing 141-160 of 363 trials

CompletedBevacizumab Plus Ipilimumab in Patients With Unresectable Stage III or IV MelanomaThe purpose of this research study is to determine the safety of using the study drugs bevacizumab and ipilimumab together, and the doses in combination which can be given to…NCT00790010·Boston, Massachusetts and 2 others CompletedA Study to Test the Effect of the Drug Larotrectinib in Adults and Children With NTRK-fusion Positive Solid TumorsThis research study is done to test how well different types of cancer respond to the drug called larotrectinib.NCT02576431·Palo Alto, California and 97 others

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Data from ClinicalTrials.govTerms

Active not recruitingStudy Assessing MTD, Safety, Tolerability, PK and Anti-tumor Effects of LNS8801alone and With PembrolizumabThis Phase 1/2, first-in-human, open-label, multicenter study follows a 3+3 ascending dose escalation design to determine the MTD/RP2D and to characterize the safety…NCT04130516·Los Angeles, California and 9 others

RecruitingHigh-Intensity Exercise and High-Fiber Diet for Immunotherapy Outcomes in Melanoma Patients: The DUO TrialThe purpose of this study is to determine whether high-intensity exercise and high-fiber diet are feasible and improve various health outcomes among participants with advanced…NCT06298734·Boston, Massachusetts and 1 other

CompletedA Phase I Study of Oral LGX818 in Adult Patients With Advanced or Metastatic BRAF Mutant MelanomaCLGX818X2101 is a first-time in-human, phase I study to establish the maximum tolerated dose (MTD) and/or recommended phase 2 dose (RP2D) of daily administered LGX818 (daily…NCT01436656·Tampa, Florida and 23 others

CompletedInvestigate Safety, Pharmacokinetics and Pharmacodynamics of GSK2118436 & GSK1120212This was an open-label, dose escalation study to investigate the safety, pharmacokinetics, pharmacodynamics and clinical activity of GSK2118436 and GSK1120212 in combination.NCT01072175·Los Angeles, California and 14 others

TerminatedA Phase III Study to Test the Benefit of a New Kind of Anti-cancer Treatment in Patients With Melanoma, After Surgical Removal of Their TumorThe purpose of this clinical trial is to evaluate the benefit of the immunotherapeutic product GSK 2132231A in preventing disease relapse when given to melanoma patients, after…NCT00796445·Birmingham, Alabama and 256 others

CompletedAn Investigational Immuno-therapy Study of Nivolumab Combined With Ipilimumab Compared to Nivolumab by Itself After Complete Surgical Removal of Stage IIIb/c/d or Stage IV MelanomaThe purpose of this study is to determine whether an investigational immunotherapy Nivolumab, when combined with Ipilimumab, is more effective than Nivolumab by itself, in…NCT03068455·Tucson, Arizona and 123 others

TerminatedNemvaleukin Alfa Monotherapy and in Combination With Pembrolizumab in Patients With Advanced Cutaneous or Mucosal Melanoma - ARTISTRY-6This study observes the antitumor activity, safety, tolerability, PK, and pharmacodynamics in patients with inoperable and/or metastatic melanomaNCT04830124·La Jolla, California and 40 others

CompletedVaccine Therapy With High-Dose Interleukin-2 in Treating Patients With Metastatic MelanomaRATIONALE: Vaccines may make the body build an immune response that will kill tumor cells. Interleukin-2 may stimulate a person's white blood cells to kill melanoma cells.NCT00003568·Duarte, California and 8 others

CompletedInterferon Alfa and Thalidomide in Treating Patients With Stage IV MelanomaRATIONALE: Interferon alfa may interfere with the growth of cancer cells and slow the growth of the tumor.NCT00026520·Mobile, Alabama and 93 others

TerminatedBRIM-P: A Study of Vemurafenib in Pediatric Patients With Stage IIIC or Stage IV Melanoma Harboring BRAFV600 MutationsThis open-label, multicenter. single arm Phase I dose-escalation study with efficacy tail extension will evaluate the maximum tolerated dose/recommended dose, the safety and…NCT01519323·Los Angeles, California and 25 others

CompletedPembrolizumab (Anti-PD-1) and AMG386 (Angiopoietin-2 (Ang-2) in Patients With Advanced Solid TumorThis research study is studying an investigational combination of drugs as a possible treatment for advanced solid tumors: melanoma, ovarian, renal, or colorectal cancer.NCT03239145·Boston, Massachusetts and 1 other

Active not recruitingInfliximab for Treatment of Immune Checkpoint Inhibitor ColitisThe goal of this clinical trial is to compare the safety and effectiveness of infliximab compared to steroids for the treatment of immune checkpoint inhibitor-induced colitis (ICI…NCT04305145·Boston, Massachusetts and 1 other

CompletedLong-term Data Collection for Subjects in MDX-010 StudiesThe objective of this study is to collect disease status and overall survival information for all Subjects in MDX-010 studies.NCT00928031·Tuscon, Arizona and 10 others

UnknownA Dose-Escalation Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of IPI-549This dose-escalation study will evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of IPI-549 monotherapy and IPI-549 in combination with nivolumab in…NCT02637531·San Diego, California and 10 others

CompletedStudy to Evaluate Treatment of Dabrafenib Plus Trametinib in Subjects With BRAF Mutation-Positive Melanoma That Has Metastasized to the BrainThis is a multi-cohort, open label, Phase II study with Dabrafenib (GSK2118436) and Trametinib (GSK1120212) combination therapy in subject with BRAF mutation-positive melanoma…NCT02039947·Birmingham, Alabama and 46 others

No longer availableExpanded Access Program With Nivolumab in Combination With Ipilimumab in Patients With Tumors Unable to be Removed by Surgery or Metastatic MelanomaThe purpose of this study is to provide treatment with nivolumab in combination with ipilimumab to subjects who are anti-(CTLA)-4 and anti-PD-1 treatment-naive and have…NCT02186249·Gilbert, Arizona and 65 others

CompletedAn Open-Label, 2-Cohort, Multicenter, Study of Lenvatinib in Previously Treated Subjects With Unresectable Stage III or Stage IV MelanomaThe purpose of this study is to assess the objective response rate of lenvatinib in previously treated participants with American Joint Committee on Cancer (AJCC) unresectable…NCT01136967·Birmingham, Alabama and 94 others

WithdrawnEfficacy and Safety of a Nanofat-seeded Biological Scaffold in Healing Lower Limb Surgical DefectsLarge full-thickness skin defects, such as those resulting from trauma, large and giant congenital nevi, disfiguring scars, or tumor resection remain major clinical problems to…NCT03548610·Boston, Massachusetts

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