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Clareo Health | Melanoma Clinical Trials in Massachusetts | 361 Studies

Clinical Trials MelanomaMassachusetts

Melanoma Clinical Trials in Massachusetts

Find 361 clinical trials for melanoma near Massachusetts. Connect with research centers in your area.

All Melanoma trials nationwide All trials in Massachusetts

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Status

RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 141-160 of 361 trials

TerminatedINCB039110 in Combination With Dabrafenib and Trametinib in Patients With BRAF-mutant Melanoma and Other Solid Tumors.This research study is studying a combination of drugs as a possible treatment for BRAF-mutant melanoma.NCT03272464·Boston, Massachusetts TerminatedA Phase 1 Study of [225Ac]-FPI-1434 InjectionThis is a first-in-human Phase 1/2, non-randomized, multi-centre, open-label clinical study designed to investigate safety, tolerability, PK, and preliminary anti-tumour activity…NCT03746431·Duarte, California and 12 others WithdrawnEfficacy and Safety of a Nanofat-seeded Biological Scaffold in Healing Lower Limb Surgical DefectsLarge full-thickness skin defects, such as those resulting from trauma, large and giant congenital nevi, disfiguring scars, or tumor resection remain major clinical problems to…NCT03548610·Boston, Massachusetts

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Data from ClinicalTrials.govTerms

Active not recruitingA Study of ABBV-927 and ABBV-181, an Immunotherapy, in Participants With Advanced Solid TumorsThis is a dose-escalation study designed to evaluate the safety, pharmacokinetics, and pharmacodynamics of ABBV-927, and to determine the maximum tolerated dose (MTD) or…NCT02988960·Los Angeles, California and 21 others

TerminatedPhase 1b Safety Study of CMB305 in Patients With Locally Advanced, Relapsed, or Metastatic Cancer Expressing NY-ESO-1This is a Phase 1b, open label, multi-center study of CMB305 (sequentially administered LV305 \[a dendritic cell-targeting viral vector expressing the NY-ESO-1 gene\] and G305…NCT02387125·Santa Monica, California and 7 others

CompletedEfficacy Study of Nivolumab Compared to Ipilimumab in Prevention of Recurrence of Melanoma After Complete Resection of Stage IIIb/c or Stage IV MelanomaThe purpose of this study is to determine whether nivolumab is better than ipilimumab to prevent recurrence of melanoma.NCT02388906·Little Rock, Arkansas and 135 others

Active not recruitingAn Efficacy Study of Adjuvant Treatment With the Personalized Cancer Vaccine mRNA-4157 and Pembrolizumab in Participants With High-Risk Melanoma (KEYNOTE-942)The purpose of this study is to assess whether postoperative adjuvant therapy with mRNA-4157 and pembrolizumab improves recurrence free survival (RFS) compared to pembrolizumab…NCT03897881·Tucson, Arizona and 22 others

UnknownIntensity-Modulated or Proton Radiation Therapy for Sinonasal MalignancyThe purpose of this study is to test the hypothesis that 1)intensity-modulated radiotherapy (IMRT) or proton radiation therapy would result in improved local control rate and…NCT01586767·Boston, Massachusetts and 1 other

CompletedA Study of XmAb®22841 Monotherapy & in Combination w/ Pembrolizumab in Subjects w/ Selected Advanced Solid TumorsThis is a Phase 1, multiple dose, ascending-dose escalation study and expansion study designed to define a maximum tolerated dose and/or recommended dose of XmAb22841 monotherapy…NCT03849469·Encinitas, California and 27 others

UnknownDose Escalation of RMC-4630 Monotherapy in Relapsed/Refractory Solid TumorsThe purpose of this study is to evaluate the safety, tolerability, pharmacokinetic (PK), and pharmacodynamic (PD) profiles of escalating doses of RMC-4630 monotherapy in adult…NCT03634982·Scottsdale, Arizona and 11 others

CompletedIpilimumab With or Without Bevacizumab in Treating Patients With Stage III-IV Melanoma That Cannot Be Removed by SurgeryThis randomized phase II trial studies how well ipilimumab with or without bevacizumab works in treating patients with stage III-IV melanoma that cannot be removed by surgery.NCT01950390·Birmingham, Alabama and 481 others

TerminatedStudy of Intratumorally Administered Stimulator of Interferon Genes (STING) Agonist E7766 in Participants With Advanced Solid Tumors or Lymphomas - INSTAL-101This is an open label, multicenter, phase 1/1b study to assess safety/tolerability and preliminary clinical activity of E7766 as a single agent administered intratumorally in…NCT04144140·New Haven, Connecticut and 12 others

CompletedStudy of Cabozantinib (XL184) in Adults With Advanced MalignanciesThis is a Phase 2 study to evaluate the efficacy and safety of cabozantinib (XL184) in subjects with selected advanced tumor types.NCT00940225·Scottsdale, Arizona and 46 others

CompletedAdoptive Transfer of MART1/Melan-A CTL for Malignant MelanomaRATIONALE: Cytotoxic T lymphocytes (CTL) are cells of the immune system that can fight infections and cancer.NCT00512889·Boston, Massachusetts

CompletedIn Vitro Expanded Autologous Invariant Natural Killer Cells in CancerThe purpose of this research study is to determine whether we can purify and grow a population of cells from the participants blood (iNKT cells) and then safely give them back to…NCT00631072·Boston, Massachusetts and 1 other

Active not recruitingA Study Evaluating AB248 Alone or in Combination With Pembrolizumab in Adult Patients With Solid TumorsThis is a phase I, First-in-Human (FIH), open-label study to evaluate the safety, tolerability, pharmacokinetic (PK) profile, and preliminary efficacy of AB248 as monotherapy OR…NCT05653882·Duarte, California and 19 others

TerminatedA Study Evaluating the Safety and Antitumor Activity of IPI-504, in Patients With Metastatic MelanomaTo evaluate the antitumor activity of IPI-504 in patients with metastatic melanoma.NCT00627419·Tuscon, Arizona and 16 others

CompletedA Study to Investigate the Safety, Pharmacokinetics, Pharmacodynamics, and Anti-Cancer Activity of Trametinib in Combination With Palbociclib in Subjects With Solid TumorsThis is a dose-escalation, Phase I/II, open-label, three-part study.NCT02065063·Boston, Massachusetts and 2 others

CompletedA Phase 3 Study of Pembrolizumab + Epacadostat or Placebo in Subjects With Unresectable or Metastatic Melanoma (Keynote-252 / ECHO-301)The purpose of the study is to assess the efficacy, safety, and tolerability when combining pembrolizumab with epacadostat or placebo in participants with unresectable or…NCT02752074·Birmingham, Alabama and 128 others

CompletedSafety, Tolerability, Immunogenicity, and Antitumor Activity of GEN-009 Adjuvanted VaccineIn this study, Genocea is evaluating an investigational, personalized adjuvanted vaccine, GEN-009, that is being developed for the treatment of patients with solid tumors.NCT03633110·La Jolla, California and 10 others

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