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Clareo Health | Depression Clinical Trials in Chicago | 177 Studies

Clinical Trials DepressionChicago

Depression Clinical Trials in Chicago

Find 177 clinical trials for depression near Chicago, Illinois. Connect with research centers in your area.

All Depression trials nationwide All trials in Chicago

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

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Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 141-160 of 177 trials

TerminatedEfficacy and Safety Study of NeuroStar TMS Therapy in Patients With Major Depressive Disorder With Postpartum OnsetThe purpose of this study is to evaluate the safety and effectiveness of acute NeuroStar TMS therapy in women who have postpartum depression.NCT01842542·Hartford, Connecticut and 7 others RecruitingA Study of Seltorexant as Monotherapy in Adults and Elderly Participants With Major Depressive DisorderThe main purpose of this study is to assess how well the study drug (JNJ-42847922) works (efficacy) compared with placebo in improving depressive symptoms in participants with…NCT07573176·Bryant, Arkansas and 38 others

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Data from ClinicalTrials.govTerms

TerminatedSelective Serotonin Reuptake Inhibitors (SSRIs) in Borderline Personality DisorderThe goal of this study is to examine the effectiveness the selective serotonin reuptake inhibitor (SSRI) escitalopram (also known by the trade name "Lexapro") in reducing desire…NCT01103180·Chicago, Illinois

RecruitingClinical Assessment of Response in the Treatment of Depression With Daytime Sleepiness Using SolriamfetolCLARITY (Clinical Assessment of Response in the Treatment of Depression with Daytime Sleepiness Using Solriamfetol) is a Phase 3, double-blind, placebo-controlled, multicenter…NCT07484217·Tucson, Arizona and 39 others

CompletedCombining Medications to Enhance Depression OutcomesThis study will compare whether a combination of antidepressant medications is better than one antidepressant medication alone when given as initial treatment for people with…NCT00590863·Tuscaloosa, Alabama and 14 others

CompletedA Efficacy Study of PRX-00023 in Patients With Major Depressive DisorderThe purpose of this randomized, double-blind, placebo-controlled study is to assess the safety and efficacy of PRX-00023 in patients with major depressive disorder.NCT00448292·Mesa, Arizona and 20 others

RecruitingA Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive DisorderThe purpose of this study is to determine the efficacy, safety and tolerability of CYB003 compared to matching placebo as adjunctive treatment in patients with MDD.NCT06793397·Birmingham, Alabama and 78 others

CompletedUnobtrusive Monitoring of Affective Symptoms and Cognition Using Keyboard Dynamics (UnMASCK)Mood disorders are associated with significant financial and health costs for the United States, partially due to cognitive problems in these patients that can worsen disease…NCT04358900·Chicago, Illinois

CompletedStudy of 6(S)-5-MTHF Among Selective Serotonin Reuptake Inhibitor-Resistant Outpatients With Major Depressive DisorderThe purpose of the study is to test whether oral 6(S)-5-MTHF (Deplin) is safe and effective in relieving depression when it is added to standard kinds of antidepressants called…NCT00955955·San Diego, California and 5 others

Completed54135419SUI3001: A Study to Evaluate the Efficacy and Safety of Intranasal Esketamine in Addition to Comprehensive Standard of Care for the Rapid Reduction of the Symptoms of Major Depressive Disorder, Including Suicidal Ideation, in Adult Participants Assessed to be at Imminent Risk for SuicideThe purpose of the study is to evaluate the efficacy of intranasal esketamine 84 milligram (mg) compared with intranasal placebo in addition to comprehensive standard of care in…NCT03039192·Birmingham, Alabama and 55 others

CompletedOpen-Label Safety Study of AXS-05 in Subjects With DepressionAn open-label, long-term, safety study of AXS-05 in patients with major depressive disorder (MDD), including treatment resistant depression.NCT04039022·Phoenix, Arizona and 50 others

CompletedNeuroStar TMS Therapy System: Utilization and OutcomesThe major objective of this observational study is to describe clinical outcomes of patients receiving treatment with the NeuroStar TMS Therapy system in routine clinical practice.NCT01114477·Phoenix, Arizona and 43 others

TerminatedA Study to Evaluate the Safety and Efficacy of TS-121 as an Adjunctive Treatment for Major Depressive DisorderThe purpose of this study is to evaluate the safety, tolerability, and efficacy of TS-121 as an adjunctive treatment for patients with major depressive disorder with an inadequate…NCT03093025·Little Rock, Arkansas and 21 others

TerminatedDeep Brain Stimulation for Major Depressive DisorderThis study is designed as a prospective, multi-centered, double-blind, randomized, controlled 12-month pivotal study to evaluate the safety and efficacy of the ANS Libra® Deep…NCT00617162·Stanford, California and 12 others

CompletedStudy to Evaluate the Efficacy and Safety of Adjunctive Pimavanserin in Major Depressive Disorder (CLARITY)To assess the efficacy of pimavanserin compared to placebo when given adjunctively to a selective serotonin reuptake inhibitor (SSRI)/serotonin-norepinephrine reuptake inhibitor…NCT03018340·Birmingham, Alabama and 35 others

CompletedA Study of Psilocybin for Major Depressive Disorder (MDD)One hundred participants, ages 21 to 65, who meet Diagnostic and Statistical Manual of Mental Disorders (DSM-5) criteria for major depressive disorder (MDD) will be stratified by…NCT03866174·San Francisco, California and 10 others

CompletedThinking Skills for Work in Severe Mental IllnessThe purpose of this study is help people with serious mental illness and receiving vocational rehabilitation get and keep the job they want by improving their thinking skills…NCT01926613·Chicago, Illinois and 1 other

CompletedA Study of Rapastinel as Adjunctive Therapy in Major Depressive Disorder (RAP-MD-02)This study will evaluate the efficacy, safety, and tolerability of two doses of rapastinel, 225 milligrams (mg) and 450 mg, compared to placebo adjunctive to antidepressant…NCT02943564·Birmingham, Alabama and 65 others

CompletedStudy Evaluating Desvenlafaxine Succinate Sustained Release (DVS SR) Versus Placebo in Peri- and Postmenopausal WomenDesvenlafaxine succinate (DVS) is a potent and selective serotonin and norepinephrine reuptake inhibitor (SNRI).NCT00369343·Birmingham, Alabama and 36 others

CompletedProject to Improve Symptoms and Mood in People With Spinal Cord InjuryDepression is likely the most prevalent and disabling psychological complication associated with spinal cord injury (SCI).NCT00592384·Birmingham, Alabama and 5 others

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