COPD Clinical Trials

Showing 1001-1020 of 1,730 trials

The Role of Congenital Mucosal Immune System in the Airways of Patients With Chronic Obstructive Pulmonary Disease

NCT04061122

The purpose of the study is to explore the role of congenital mucosal immune system in the airways of patients with COPD including the impact of ILCs (Innate lymphoid cells) on metabolism of epithelial cells.During the research the following methods will be applied: measurement of Volatile Organic Compounds (VOCS), airway epithelial cytology and culture.

COPD ExacerbationSmoking, Tobacco

Medical University of Lodz40 participantsStarted Jul 2018

Lodz, Poland

UNKNOWNPhase 2

Morphine to Maximize the Benefits of Exercise Training in COPD or ILD and Persistent Breathlessness

NCT03824834

The purpose of this study is to explore the role of low-dose immediate-release oral morphine as a novel adjunct pharmacotherapy to enable symptomatic adults with advanced chronic obstructive pulmonary disease (COPD) or interstitial lung disease (ILD) to exercise at higher intensities for longer durations and maximize the psycho-physiological benefits of a supervised exercise training program. We hypothesize that, compared to placebo, exercise training with oral morphine will result in relatively greater improvements in exercise endurance time and intensity ratings of perceived breathlessness during constant-load cardiopulmonary cycle exercise testing (CPET) at 75% of peak power output (PPO).

Chronic Obstructive Pulmonary DiseaseInterstitial Lung Disease

Dennis Jensen, Ph.D.40 participantsStarted Aug 2019

Montreal, Quebec, Canada

The Role of Congenital Mucosal Immune System in the Airways of Patients With Chronic Obstructive Pulmonary Disease

Morphine to Maximize the Benefits of Exercise Training in COPD or ILD and Persistent Breathlessness

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Effect of Acetazolamide on Right Ventricular Function at Rest in Patients With Respiratory Disease at Altitude

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Hospitalary Chronic Obstructive Pulmonary Disease Registry

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Evaluation of a Multi-professional Breathlessness Service for Patients With Breathlessness Due to Any Advanced Disease

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The Trajectory of Physical Activity Following Pulmonary Rehabilitation

Effects of Combined Cognitive Rehabilitation in COPD Patients

Efficacy and Mechanism of NIV in Relieving Dyspnea After Exercise in Patients With Stable Severe COPD

Evaluation of CO2 Rebreathing During Exercise With the Increasing Ventilation Assisted by NIV With a Dual-limb Circuit

A Study to Assess the Effects of PT001 and PT005 MDI on Specific Image Based Parameters in Subjects With Moderate to Severe COPD

Effectiveness of the Geriatric Activation Program Pellenberg (GAPP) on the Geriatric Rehabilitation Ward

Alpha-1 Carrier Genomics Study

Patient Oriented Discharge Summary Impact Study

Effectiveness of Vibrating Mesh Versus Small Volume Nebuliser in Chronic Obstructive Pulmonary Disease (COPD)

Structured Discharge and Follow-up Protocol for COPD Patients Receiving LTOT and NIV