COPD Clinical Trials

Showing 761-780 of 1,730 trials

Comparative Effectiveness and Safety of Tiotropium and Olodaterol in Comparison to LABA/ICS

NCT04138758

The primary objective is to compare the effectiveness of maintenance therapy initiation with the combination treatment Tiotropium and Olodaterol (Olo+Tio) compared with LABA/ICS combination in COPD as the time to the first COPD exacerbation. Secondary objectives are to compare patients treated with Tio+Olo and patients treated with LABA/ ICS combination.

COPD

Boehringer Ingelheim42,953 participantsStarted Nov 2019

Watertown, Massachusetts, United States

UNKNOWN

Effect of BDP/Formoterol/G on Cough Efficacy in Moderate to Severe COPD Patients (EFFICACE)

NCT05114434

This prospective, single centre, 8 weeks, open-label study is designed to evaluate in real-life the effect of triple Beclometasone/Formoterol/Glycopyrronium (BDP/F/G) therapy on cough efficacy, assessed by cough peak flow (CPF), after 8 weeks' treatment in patients with moderate to severe COPD. The study's hypothesis is that in symptomatic moderate to severe COPD patients the administration of fixed dose combination BDP/F/G, by reducing lung hyperinflation (LH) and targeting small airways, may accordingly improve the cough efficacy. The increase in cough efficacy might in turn positively influence the quality of life of patients and underlie the prevention of acute exacerbations of COPD.

COPD, Chronic Obstructive Pulmonary Disease

University of Parma40 participantsStarted Nov 2021

Parma, Italy

TERMINATEDPhase 1

Study in Healthy Volunteers and COPD Patients to Evaluate the Efficacy and Safety of Inhaled TV46017

NCT02315131

The primary objective of the study is to characterize the safety profile and duration of bronchodilation of a single dose of inhaled TV46017

Chronic Obstructive Pulmonary Disease (COPD

Teva Branded Pharmaceutical Products R&D, Inc.53 participantsStarted Mar 2015

St Louis, Missouri, United States • Raleigh, North Carolina, United States • Adelaide, Australia +4 more locations

Comparative Effectiveness and Safety of Tiotropium and Olodaterol in Comparison to LABA/ICS

Effect of BDP/Formoterol/G on Cough Efficacy in Moderate to Severe COPD Patients (EFFICACE)

Study in Healthy Volunteers and COPD Patients to Evaluate the Efficacy and Safety of Inhaled TV46017

Related Searches

An Efficacy and Safety Profile of Inhaled TV48108 in Healthy Volunteers and COPD Patients

A Study of 3 Doses of Tiotropium Hydrofluoralkane (HFA) Breath Actuated Inhaler (BAI), in Patients With Chronic Obstructive Pulmonary Disease

Functional Proteomics of Alveolar Macrophages

2-arm Parallel Group Study of Fixed Combination of CHF 5993 vs Ultibro® in COPD Patients

Pharmacokinetic Interaction Study of Glycopyrrolate and Formoterol in Healthy Volunteers

An Open Label Placebo Study To Assess The Inhalation Profile Obtained By Acoustic Monitoring In COPD Patients Using The NEXThaler DPI

A Phase II, 5-way Cross-over Study to Evaluate the Pharmacodynamics of "Nexthaler" Dry Powder Inhaler in COPD Patients

Efficacy of Fixed Combination of Beclometasone + Formoterol + Glycopyrrolate Versus Foster® in COPD

A Study to Investigate the Pharmacokinetics, Safety and Tolerability of CHF 5993 pMDI in Subjects With Renal Impairment.

The Effect of HFNC on Exercise Capacity Compared to VM in COPD Patients Recovering From Acute Evacerbation

Diastolic Dysfunction and Pauci-inflammatory Acute Exacerbations of COPD

A Proof-of-mechanism Study of Multiple, Oral Doses of Fevipiprant (QAW039) in COPD Patients With Eosinophilia

Study on the Etiology, Risk Factors and Pathogenesis of COPD Based on Clinical Bioinformatics

Intervention for Resistant Pregnant Smokers

Respiratory Disorders Non-invasive Monitoring of Work of Breathing in Outpatients

Switch of Budesonide-formoterol Dry Powder Inhalers at Pharmacy in Norway

Studying the Airway Microenvironment in Patients Undergoing Surgical and Bronchoscopic Interventions for COPD