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Clareo Health | Colorectal Cancer Clinical Trials in Ohio | 390 Studies

Clinical Trials Colorectal CancerOhio

Colorectal Cancer Clinical Trials in Ohio

Find 390 clinical trials for colorectal cancer near Ohio. Connect with research centers in your area.

All Colorectal Cancer trials nationwide All trials in Ohio

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Status

RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4Not applicable

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Showing 41-60 of 390 trials

CompletedSotorasib and Panitumumab Versus Investigator's Choice for Participants With Kirsten Rat Sarcoma (KRAS) p.G12C MutationThe aim of the study is to compare progression-free survival (PFS) in previously treated participants with Kirsten rat sarcoma (KRAS) p.G12C mutated colorectal cancer (CRC)…NCT05198934·Birmingham, Alabama and 104 others

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Data from ClinicalTrials.govTerms

CompletedCOM701 (an Inhibitor of PVRIG) in Subjects With Advanced Solid Tumors.This is a Phase 1 open label sequential dose escalation and cohort expansion study evaluating the safety, tolerability and preliminary clinical activity of COM701 as monotherapy…NCT03667716·Los Angeles, California and 10 others

CompletedBevacizumab and Oxaliplatin Combined With Irinotecan or Leucovorin and Fluorouracil in Treating Patients With Metastatic or Recurrent Colorectal CancerRATIONALE: Drugs used in chemotherapy, such as oxaliplatin, irinotecan, leucovorin, and fluorouracil, work in different ways to stop the growth of tumor cells, either by killing…NCT00098787·Greenbrae, California and 109 others

RecruitingPhase 1 Study Evaluating the Safety and PK of ADU-1805 in Advanced Solid TumorsThis first-in-human, open-label, multicenter, multi-arm dose-escalation study is designed to evaluate the safety, PK, and PD of ADU-1805, an anti- SIRPα monoclonal antibody, as…NCT05856981·Detroit, Michigan and 10 others

No longer availableRegorafenib in Subjects With Metastatic Colorectal Cancer (CRC) Who Have Progressed After Standard TherapyThis is a phase III B, prospective, interventional, open-label, single-arm, multicenter study to provide regorafenib to subjects diagnosed with metastatic colorectal cancer who…NCT01538680·Duarte, California and 206 others

WithdrawnRegional Anesthesia in Colon Rectal SurgeryThis study will compare recurrence rates in patients with colorectal cancer who will be randomly assigned to epidural anesthesia/analgesia combined with general anesthesia or to…NCT00684229·Cleveland, Ohio and 2 others

CompletedDetection of Advanced Colorectal Neoplasia by Stool DNA in Inflammatory Bowel DiseaseThis study aims to determine the performance of the Exact IBD-ACRN surveillance test to detect colorectal cancer (CRC) and colorectal neoplasia in patients with inflammatory bowel…NCT01819766·Phoenix, Arizona and 25 others

CompletedA Multicenter Phase 2 Study of CI-1040 in Patients With Advanced Nonsmall-Cell Lung, Breast, Colon and Pancreatic CancerCI-1040 is an experimental drug that is being tested in patients who have advanced colorectal and lung cancer who failed no more than one prior chemotherapy regimen, breast cancer…NCT00034827·Birmingham, Alabama and 29 others

RecruitingStudy of RMC-9805 in Participants With KRAS G12D-Mutant Solid TumorsThis study is to evaluate the safety and tolerability of RMC-9805 as monotherapy and in combination with RMC-6236 in adults with KRAS G12D-mutant solid tumors.NCT06040541·Sacramento, California and 16 others

CompletedA Study Combining FOLFOX or FOLFIRI With AG-013736 or Bevacizumab (Avastin) in Patients With Metastatic Colorectal Cancer After Failure Of One First Line RegimenThe study is designed to demonstrate that the combination of AG-013736 with either FOLFIRI or FOLFOX is superior to FOLFIRI or FOLFOX in combination with bevacizumab (Avastin) in…NCT00615056·Mobile, Alabama and 82 others

TerminatedPF-06671008 Dose Escalation Study in Advanced Solid TumorsThe study will evaluate the safety, pharmacokinetics and pharmacodynamics of increasing doses of PF-06671008 in patients with advanced solid tumors with the potential to have…NCT02659631·Harrison, New York and 8 others

CompletedOpen-label, Single Arm Trial of BI 695502 in Patients With Previously Untreated Metastatic Colorectal CancerThe objective of this trial is to evaluate the safety and tolerability of BI 695502 in combination with leucovorin/5-fluorouracil/oxaliplatin (mFOLFOX6) and as maintenance therapy…NCT02776683·Phoenix, Arizona and 45 others

CompletedSWOG-S9635 Fluorouracil Plus Ethynyluracil in Advanced Colorectal Cancer Not Responded to FluorouracilRATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.NCT00003254·Mobile, Alabama and 85 others

CompletedQUILT-2.018: Safety & Efficacy of FOLFIRI With AMG 479 or AMG 655 vs FOLFIRI Alone in KRAS-mutant Metastatic Colorectal CarcinomaThis is a phase 2, multicenter, randomized, double-blind, double-dummy, placebo-controlled, three-arm trial to be conducted in the United States, Europe, and Asia.NCT00813605·Beverly Hills, California and 66 others

CompletedGene Testing in Patients With Colon CancerRATIONALE: Analyzing the structure of genes found in a person's cancer cells may help doctors improve methods of treating patients with colon cancer.NCT00003571·Birmingham, Alabama and 43 others

RecruitingA Study of PARG Inhibitor ETX-19477 in Patients With Advanced Solid MalignanciesThis is a two-part, open-label, multicenter, dose escalation and dose expansion study designed to evaluate the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PDx)…NCT06395519·Phoenix, Arizona and 13 others

RecruitingPost-Market Study of the Signia Circular Stapler With Tri-Staple Technology in Left-sided Colon, Sigmoid, and Rectal ResectionsThe purpose of this study is to evaluate the safety and performance of the Signia™ power handle, Signia™ circular adapter, and Signia™ Tri-Staple™ 2.0 circular reloads (hereafter…NCT07351071·New Haven, Connecticut and 9 others

CompletedA Study of Napabucasin (BBI-608) in Combination With FOLFIRI in Adult Patients With Previously Treated Metastatic Colorectal CancerThis is an international multi-center, prospective, open-label, randomized, adaptive design phase 3 trial of the cancer stem cell pathway inhibitor napabucasin plus standard…NCT02753127·Birmingham, Alabama and 210 others

RecruitingHistotripsy Plus Chemotherapy vs Chemotherapy Alone for Advanced Colorectal Liver MetastasisThe goal of this clinical trial is to learn if histotripsy plus chemotherapy works to treat unresectable, bilobar liver- confined colorectal cancer liver metastasis (CRLM).NCT07044362·Cleveland, Ohio

CompletedNintedanib (BIBF 1120) vs Placebo in Refractory Metastatic Colorectal Cancer (LUME-Colon 1)The objective of this Phase III study is to evaluate the efficacy of nintedanib in patients with metastatic colorectal cancer (mCRC) after failure of previous treatment with…NCT02149108·Los Angeles, California and 128 others

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Other Conditions in Ohio

Breast Cancer Lung Cancer Prostate Cancer Melanoma Leukemia Lymphoma