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Regional Anesthesia in Patients Undergoing Colon-Rectal Surgery
This study will compare recurrence rates in patients with colorectal cancer who will be randomly assigned to epidural anesthesia/analgesia combined with general anesthesia or to general anesthesia followed by opioid analgesia.
The study population will consist of patients who are scheduled for open laparoscopic or laparoscopic assisted surgery for colon cancer. Patients will randomized into one of two groups. The intervention group will receive combined regional and general anesthesia during surgery. Postoperative pain treatment will be based on regional anesthesia techniques. The Control group will receive general anesthesia during surgery. Postoperative pain treatment will be based primarily on opioids. After surgery, patients will be followed daily during their hospital stay. Patients will be contacted by telephone every 6 months for five years. Quality of life questionnaires will be administered at these follow ups.
Age
18 - 85 years
Sex
ALL
Healthy Volunteers
No
Cleveland Clinic
Cleveland, Ohio, United States
Hospital Italiano de Buenos Aires
Buenos Aires, Argentina
University of Dusseldorf
Düsseldorf, Germany
Start Date
December 1, 2007
Primary Completion Date
November 1, 2013
Completion Date
November 1, 2013
Last Updated
September 15, 2016
Regional anesthesia and analgesia
PROCEDURE
general anesthesia followed by opioid analgesia
DRUG
Lead Sponsor
The Cleveland Clinic
NCT04704661
NCT04674267
Data Source & Attribution
This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.
Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.
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