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Clareo Health | Lung Cancer Clinical Trials in Ohio | 878 Studies

Clinical Trials Lung CancerOhio

Lung Cancer Clinical Trials in Ohio

Find 878 clinical trials for lung cancer near Ohio. Connect with research centers in your area.

All Lung Cancer trials nationwide All trials in Ohio

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4Not applicable

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Showing 1-20 of 878 trials

TerminatedStudy to Evaluate Safety, Pharmacokinetics, and Efficacy of Rociletinib (CO-1686) in Previously Treated Mutant Epidermal Growth Factor Receptor (EGFR) in Non-Small Cell Lung Cancer (NSCLC) PatientsRociletinib is a novel, potent, small molecule irreversible tyrosine kinase inhibitor (TKI) that selectively targets mutant forms of the epidermal growth factor receptor (EGFR)…NCT01526928·Duarte, California and 48 others

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Data from ClinicalTrials.govTerms

CompletedA Study Of PF-06463922 An ALK/ROS1 Inhibitor In Patients With Advanced Non Small Cell Lung Cancer With Specific Molecular AlterationsPhase 1 and 2 trial to study the safety, pharmacokinetics, pharmacodynamics, patient reported outcomes and efficacy of PF-06463922 in ALK + advanced non-small cell lung cancer…NCT01970865·Fayetteville, Arkansas and 76 others

CompletedA Global Study to Assess the Effects of MEDI4736 (Durvalumab), Given as Monotherapy or in Combination With Tremelimumab Determined by PD-L1 Expression Versus Standard of Care in Patients With Locally Advanced or Metastatic Non Small Cell Lung CancerThis study is a Phase III, randomised, open label, multi-centre study assessing the efficacy and safety of MEDI4736 (durvalumab) versus Standard of Care in NSCLC patients with…NCT02352948·Chandler, Arizona and 200 others

CompletedA Phase 1b Study of MEDI4736 in Combination With Tremelimumab in Subjects With Advanced Non-small Cell Lung CancerThe purpose of this study is to determine if MEDI4736 will be adequately tolerated in combination with tremelimumab in subjects with advanced non-small cell lung cancer (NSCLC).NCT02000947·Birmingham, Alabama and 68 others

TerminatedMarrow Infiltrating Lymphocytes - Non-Small Cell Lung Cancer (MILs™ - NSCLC) Alone or in Combination With Nivolumab With or Without Tadalafil in Locally Advanced and Unresectable or Metastatic NSCLCThe purpose of this study is to determine the safety and efficacy of MILs™ - NSCLC alone and in combination with nivolumab with or without tadalafil in subjects with locally…NCT04069936·Duarte, California and 9 others

Active not recruitingBeamion LUNG-2: A Study to Test Whether Zongertinib (BI 1810631) Helps People With Advanced Non-small Cell Lung Cancer With HER2 Mutations Compared With Standard TreatmentThis study is open to adults 18 years and older with advanced or metastatic non-small cell lung cancer.NCT06151574·Huntsville, Alabama and 162 others

Active not recruitingEnhanced Dermatological Care to Reduce Rash and Paronychia in Epidermal Growth Factor Receptor (EGRF)-Mutated Non-Small Cell Lung Cancer (NSCLC) Treated First-line With Amivantamab Plus LazertinibThe purpose of this study is to evaluate whether enhanced dermatologic management can reduce incidence of grade greater than or equal to (\>=) 2 dermatologic adverse events of…NCT06120140·Chandler, Arizona and 92 others

CompletedChemotherapy and Radiation in Treating Participants With Stage 3 Non-Small Cell Lung CancerThis study will compare the overall survival of participants with locally-advanced, Stage III Non-Small Cell Lung Cancer (NSCLC) with nonsquamous cell histology.NCT00686959·Birmingham, Alabama and 132 others

Active not recruitingTesting the Addition of Radiation Therapy to the Usual Treatment (Immunotherapy With or Without Chemotherapy) for Advanced Stage Non-small Cell Lung Cancer Patients Who Are PD-L1 NegativeThis phase II/III trial compares the addition of radiation therapy to the usual treatment (immunotherapy with or without chemotherapy) versus (vs.) usual treatment alone in…NCT04929041·Phoenix, Arizona and 168 others

Active not recruitingStudy of JANX008 in Subjects With Advanced or Metastatic Solid Tumor MalignanciesThis study is a first-in-human (FIH), Phase 1/1b, open-label, multicenter dose escalation and dose expansion study to assess the safety, tolerability, pharmacokinetics (PK)…NCT05783622·Duarte, California and 17 others

CompletedErlotinib + Bevacizumab for PS 2 Chemotherapy Naïve Non-Small Cell Lung CancerThe strategy for combining therapeutic agents in cancer treatments has been successful in multiple tumor types, including NSCLC.NCT00367601·Galesburg, Illinois and 12 others

TerminatedTIGER-3: Open Label, Multicenter Study of Rociletinib (CO-1686) Mono Therapy Versus Single-agent Cytotoxic Chemotherapy in Patients With Mutant EGFR NSCLC Who Have Failed at Least One Previous EGFR-Directed TKI and Platinum-doublet ChemotherapyThe purpose of this study is to compare the anti-tumor efficacy of oral single-agent rociletinib, as measured by investigator assessment of the PFS, with that of single-agent…NCT02322281·Bakersfield, California and 79 others

CompletedA Study of DF6002 Alone and in Combination With NivolumabThe purpose of this study is to evaluate the safety, tolerability, drug-levels, drug-effects and preliminary anti-tumor activity of DF6002 alone and in combination with Nivolumab…NCT04423029·Orange, California and 31 others

RecruitingLung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung CancerThis screening and multi-sub-study randomized phase II/III trial will establish a method for genomic screening of similar large cancer populations followed by assigning and…NCT03851445·Birmingham, Alabama and 1228 others

CompletedA Double-blind Study Evaluating IPI-504 and Docetaxel in Patients With Non-Small Cell Lung CancerThe purpose of this study is to compare the impact of IPI-504 in combination with docetaxel to placebo in combination with docetaxel on life expectancy in patients with Non Small…NCT01362400·Chandler, Arizona and 64 others

Active not recruitingTesting the Safety of M6620 (VX-970) When Given With Standard Whole Brain Radiation Therapy for the Treatment of Brain Metastases From Non-small Cell Lung Cancer, Small Cell Lung Cancer, or Neuroendocrine TumorsThis phase I trial studies the side effects and best dose of berzosertib (M6620 \[VX-970\]) when given together with whole brain radiation therapy in treating patients with…NCT02589522·Duarte, California and 8 others

Active not recruitingSacituzumab Tirumotecan (MK-2870) Versus Chemotherapy in Previously Treated Advanced or Metastatic Nonsquamous Non-small Cell Lung Cancer (NSCLC) With EGFR Mutations or Other Genomic Alterations (MK-2870-004)The purpose of this study is to evaluate sacituzumab tirumotecan versus chemotherapy (docetaxel or pemetrexed) for the treatment of previously-treated non-small cell lung cancer…NCT06074588·Los Angeles, California and 194 others

CompletedPembrolizumab/Vibostolimab Coformulation (MK-7684A) or Pembrolizumab/Vibostolimab Coformulation Plus Docetaxel Versus Docetaxel for Metastatic Non Small Cell Lung Cancer (NSCLC) With Progressive Disease After Platinum Doublet Chemotherapy and Immunotherapy (MK-7684A-002, KEYVIBE-002)The main purpose of this study is to compare pembrolizumab/vibostolimab coformulation (MK-7684A) plus docetaxel or pembrolizumab/vibostolimab coformulation to normal saline…NCT04725188·Los Angeles, California and 94 others

CompletedBrentuximab Vedotin With Pembrolizumab in Metastatic Solid TumorsThis trial will find out whether brentuximab vedotin and pembrolizumab work together to treat different types of cancer.NCT04609566·Tucson, Arizona and 89 others

CompletedA Phase 2 Study to Determine the Safety and Efficacy of BIND-014 (Docetaxel Nanoparticles for Injectable Suspension) as Second-line Therapy to Patients With Non-Small Cell Lung CancerThe purpose of this study is to evaluate the efficacy and safety of BIND-014 in patients with advanced non-small cell lung cancer (NSCLC).NCT01792479·Goodyear, Arizona and 16 others

Other Conditions in Ohio

Breast Cancer Prostate Cancer Colorectal Cancer Melanoma Leukemia Lymphoma