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Clareo Health | Melanoma Clinical Trials in Ohio | 325 Studies

Clinical Trials MelanomaOhio

Melanoma Clinical Trials in Ohio

Find 325 clinical trials for melanoma near Ohio. Connect with research centers in your area.

All Melanoma trials nationwide All trials in Ohio

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

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Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 1-20 of 325 trials

TerminatedOral AMXT 1501 Dicaprate in Combination With IV DFMOA Phase 1B/2A study will be conducted to establish safety and dose level of AMXT 1501 dicaprate in combination with IV DFMO, in cancer patients.NCT05500508·Phoenix, Arizona and 6 others WithdrawnNeoadjuvant Nivolumab+Ipilimumab Followed by Adjuvant Nivolumab or Neoadjuvant Nivolumab+Ipilimumab Followed by Adjuvant Observation Compared With Adjuvant Nivolumab in Treatment-Naive High-risk Melanoma ParticipantsThe purpose of this study is to evaluate the role of neoadjuvant immunotherapy and to demonstrate high pathologic complete response (pCR) and near pCR rates in melanoma…NCT04495010·Gilbert, Arizona and 117 others

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Data from ClinicalTrials.govTerms

RecruitingA Study Assessing KB707 for the Treatment of Locally Advanced or Metastatic Solid TumorsKB707-01 is a Phase 1/2, open-label, multicenter, dose escalation and expansion study.NCT05970497·Los Angeles, California and 14 others

RecruitingTebentafusp Regimen Versus Investigator's Choice in Previously Treated Advanced Melanoma (TEBE-AM)The purpose of this study is to evaluate the efficacy and safety of tebentafusp-based regimens, including tebentafusp monotherapy and in combination with anti-PD1 vs investigator…NCT05549297·Phoenix, Arizona and 81 others

CompletedIpilimumab With or Without Talimogene Laherparepvec in Unresected MelanomaPhase 1b of the study will evaluate the safety of talimogene laherparepvec in combination with ipilimumab.NCT01740297·Tucson, Arizona and 39 others

CompletedA Study of RO5185426 in Patients With Metastatic MelanomaThis is an open-label, non-comparative, multicenter, expanded access study of RO5185426 in patients who have received prior systemic therapy for metastatic melanoma and who have…NCT01248936·Tucson, Arizona and 27 others

CompletedSafety and Efficacy Study of GC1008 to Treat Renal Cell Carcinoma or Malignant MelanomaThe purpose of this study is to determine the safety, tolerability, pharmacokinetics and pharmacodynamics of GC1008, a human anti-transforming growth factor-beta (TGFβ) monoclonal…NCT00356460·Bethesda, Maryland and 5 others

RecruitingPan-tumor MRD StudyThe purpose of this observational study is to collect clinical information, blood, and tumor tissue samples from participants diagnosed with stage I, stage II, or operable stage…NCT06605404·Birmingham, Alabama and 46 others

SuspendedPropranolol Hydrochloride and Pembrolizumab in Treating Patients With Stage IIIC-IV Melanoma That Cannot Be Removed by SurgeryThis phase Ib/II trial studies the side effects and best dose of propranolol hydrochloride when given together with pembrolizumab and how well they work in treating patients with…NCT03384836·Atlanta, Georgia and 3 others

TerminatedA Phase III Study to Test the Benefit of a New Kind of Anti-cancer Treatment in Patients With Melanoma, After Surgical Removal of Their TumorThe purpose of this clinical trial is to evaluate the benefit of the immunotherapeutic product GSK 2132231A in preventing disease relapse when given to melanoma patients, after…NCT00796445·Birmingham, Alabama and 256 others

RecruitingNatural Killer Cell Therapy (UD TGFbetai NK Cells) and Temozolomide for the Treatment of Stage IV Melanoma Metastatic to the BrainThis phase I/II trial tests the safety, side effects, and best dose of universal donor UD TGFbetai natural killer (NK) cells, and whether UD TGFbetai NK cells with temozolomide…NCT05588453·Columbus, Ohio

Active not recruitingDinaciclib in Treating Patients With Stage IV MelanomaThis phase II trial is studying the side effects and how well dinaciclib works in treating patients with stage IV melanoma.NCT00937937·Mobile, Alabama and 189 others

RecruitingStudy of RMC-6236 in Patients With Advanced Solid Tumors Harboring Specific Mutations in RASEvaluate the safety and tolerability of RMC-6236 in adults with specific RAS mutant advanced solid tumors.NCT05379985·Orange, California and 20 others

RecruitingStudy of AMXT 1501 and DFMO in Combination With Standard Therapies in Advanced Solid TumorsThis study will evaluate the safety, tolerability, and preliminary effectiveness of AMXT 1501 and DFMO when combined with standard treatments for advanced solid tumors.NCT07287917·Tucson, Arizona and 19 others

RecruitingA Clinical Study to Test if an Investigational Treatment Called BNT326 is Safe and Potentially Beneficial When Used Alone or in Combination With Other Investigational Treatments Such as BNT327, for People With Advanced Malignant TumorsThis study will evaluate the safety, efficacy, optimal dose, and pharmacokinetics (PK) of BNT326 as monotherapy (Part 1) and as combination treatment with immunotherapeutic agents…NCT07070232·Phoenix, Arizona and 75 others

CompletedA Study of CDX-1127 (Varlilumab) in Patients With Select Solid Tumor Types or Hematologic CancersThis is a study of CDX-1127, a therapy that targets the immune system and may act to promote anti-cancer effects.NCT01460134·Scottsdale, Arizona and 9 others

CompletedStudy of ILX651 in Patients With Inoperable Locally Advanced or Metastatic MelanomaThis is a Phase II, non-randomized, open label study of ILX651 in patients with inoperable locally advanced or metastatic melanoma.NCT00068211·Scottsdale, Arizona and 18 others

TerminatedKZR-261 in Subjects With Advanced Solid MalignanciesA first-in-human, open-label, multicenter, Phase 1 study of KZR-261 designed to assess the safety and tolerability, preliminary anti-tumor activity, and pharmacokinetics (PK) of…NCT05047536·Los Angeles, California and 11 others

CompletedCarboplatin and Paclitaxel With or Without Sorafenib Tosylate in Treating Patients With Stage III or Stage IV Melanoma That Cannot Be Removed by SurgeryThis randomized phase III trial studies carboplatin, paclitaxel, and sorafenib tosylate to see how well they work compared to carboplatin and paclitaxel in treating patients with…NCT00110019·Birmingham, Alabama and 218 others

TerminatedAutologous Dendritic Cell-Tumor Cell Immunotherapy for Metastatic MelanomaThe purpose of this research is to evaluate the safety and effectiveness of tumor cell therapy.NCT01875653·Irvine, California and 17 others

Other Conditions in Ohio

Breast Cancer Lung Cancer Prostate Cancer Colorectal Cancer Leukemia Lymphoma