A Multicenter Phase 2 Study of CI-1040 in Patients With Advanced Nonsmall-Cell Lung, Breast, Colon and Pancreatic Cancer

Inclusion Criteria

• •Patients who are at least 18 years or older who have pathological or hiostological confirmation of colorectal, nonsmall cell lung cancer, breast, or pancreas cancer.
• •No more than 1 prior chemo for lung or colon cancer, no more than 2 for breast no prior chemotherapy for pancreas cancer.
• •Original or recent tumor tissue must be available.
• •Patients must have been off prior chemoptherapy for 4 weeks and radiation for 3 weeks.
• •Patients must have adequate renal, liver, and bone marrow function, not have serious infection or life-threatening illness (unrelated to tumor).
• •Must be able to swallow capsules and not have gastrointestinal disorders that may affect absorption of the drug.