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1–20 of 3,375
Completed
Supported Employment in Patient Aligned Care Teams
In response to the Rehabilitation Research and Development (RR\&D) Deployment Health Research, this study addresses the delivery of an evidenced-based vocational rehabilitation…
NCT02400736
·
Tuscaloosa, Alabama
Completed
A Study of LY2216684 in Participants With Major Depression Disorder
The primary objective of this study is to evaluate the long-term safety and tolerability of LY2216684 administered once daily in the adjunctive treatment with an Selective…
NCT01370499
·
Chiba and 8 others
Completed
D-serine Supplementation for Depression
The glutamate system is emerging as target for the development of novel antidepressant medication, in particular compounds modulating the NMDA receptor.
NCT04721249
·
Basel, Canton of Basel-City
Recruiting
Sleep TMS for Depression
The goal of this study is to establish the feasibility, tolerability, and preliminary efficacy of sleep-state transcranial magnetic stimulation (TMS) for enhancing plasticity in…
NCT06824415
·
Stanford, California
Unknown
Acupuncture for Patients With Major Depressive Disorder
Several studies investigating acupuncture for major depressive disorder (MDD) have been carried out.
NCT05106868
Terminated
A Study of Seltorexant as Adjunctive Therapy to Antidepressants in Adult and Elderly Participants With Major Depressive Disorder With Insomnia Symptoms Who Have Responded Inadequately to Antidepressant Therapy
The purpose of this study is to assess the efficacy of Seltorexant compared with placebo as adjunctive therapy to an antidepressant in improving depressive symptoms in…
NCT04532749
·
Phoenix, Arizona and 79 others
Active not recruiting
Mindfulness Engaged Neurostimulation for Depression
Repetitive Transcranial Magnetic stimulation (rTMS) is an FDA-approved therapy for treatment resistant depression (TRD) that involves brief magnetic stimulation pulses on the…
NCT06399406
·
La Jolla, California
Completed
DBS for Treatment Resistant Depression
The purpose of this study is to examine the effects of sub-callosal cingulate (SCC) deep brain stimulation (DBS) in patients with treatment resistant depression (TRD).
NCT01983904
·
Calgary, Alberta
Terminated
Comparison of Behavioral Activation and Antidepressant Medication in the Treatment of Adolescents With Depression
This study focuses on treating adolescents with depression. The study has two main purposes.
NCT01740726
·
Atlanta, Georgia
Recruiting
At-Home tDCS as Maintenance Therapy
The primary purpuse of this pilot study is to find out whether a home-based transcranial direct current stimulation (tDCS) program is feasible and well tolerated as maintenance…
NCT07269964
·
München, Bavaria and 1 other
Completed
Study of Safety, Tolerability and Pharmacokinetics of NRX-1074 in Normal Healthy Volunteers
The purpose of this study is to assess the safety and tolerability of multiple oral (PO) ascending doses of NRX-1074 in normal healthy volunteers.
NCT02366364
·
Chicago, Illinois
Completed
Effectiveness of rTMS With Double-Cone-Coil in Patients With Major Depression
Repetitive Transcranial Magnetic Stimulation (rTMS) is used to modulate the neuronal excitability in patients with depression.
NCT01460758
·
Regensburg
Withdrawn
Vortioxetine in Patients With Major Depressive Disorder and Coronary Artery Disease
This is a preliminary, open-label, clinical trial designed to assess the efficacy, safety, and tolerability of vortioxetine for the treatment of major depressive disorder in…
NCT02454426
·
Philadelphia, Pennsylvania
Completed
Comparing Group Therapies for Veterans With Depression and PTSD
Cognitive behavioral therapy (CBT) is a brief, efficient, and effective psychotherapy for individuals with depressive and PTSD.
NCT03979040
·
Charleston, South Carolina
Completed
Collaborative Depression Care Management in Treating Depressed Low-income Hispanics With Diabetes
This study will evaluate the effectiveness of culturally adapted depression treatment for reducing depressive symptoms and improving adherence to diabetes self-care regimens in…
NCT00709150
·
Los Angeles, California
Completed
A Qualitative Analysis of Youth Responses to Depression Education Delivered on Social Media
Depression is a common mental disorder among adolescents, with increased rates during the COVID-19 pandemic.
NCT07100548
·
Munich, Bavaria
Recruiting
Peripheral Neuroimmune Mechanisms of Hyperthermia
The goal of this study is to examine how whole-body hyperthermia affects the thermoinflammatory profile, which includes the combined immune and heat shock response, in patients…
NCT05366270
·
Boston, Massachusetts
Completed
Safety and Effectiveness Study of BCI-540 Versus Placebo in the Treatment of Major Depressive Disorder With Concomitant Anxiety
The purpose of this study is to determine whether BCI-540 80 mg given once daily (q.d.) or three times daily (t.i.d.) is effective in the treatment of major depression with…
NCT00621270
·
Edmonton, Alberta and 15 others
Active not recruiting
EMA-Guided Maintenance TMS for Depression
The goal of this study is to evaluate the use of ecological-momentary-assessment (EMA) as a method for scheduling maintenance treatments for patients with Major Depressive…
NCT06145594
·
Providence, Rhode Island
Completed
Sedating Antidepressant Improves Driving Safety in Patients With Major Depressive Disorder
This concurrent, two-part study will: I) Using overnight sleep recordings, evaluate the short- and long-term sleep-promoting effects of the antidepressant mirtazapine (Remeron)…
NCT00385437
·
Toronto, Ontario
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