Clinical Trials in Pittsburgh

Showing 15321-15340 of 18,076 trials

Phase I/II Trial of Intracerebral IL13-PE38QQR Infusions in Pediatric Patients With Recurrent Malignant Glioma

NCT00378235

IL13-PE38QQR is an oncology drug product consisting of IL13 (interleukin-13) and PE38QQR (a bacteria toxin). IL3-PE38QQR is a protein that exhibits cell killing activity against a variety of IL13-receptor positive tumor cell lines indicating that it may show a therapeutic benefit. In reciprocal competition experiments, the interaction between IL13-PE38QQR and the IL13 receptors was shown to be highly specific for human glioma cells.

Recurrent Malignant Glioma

INSYS Therapeutics Inc

San Francisco, California, United States • Washington D.C., District of Columbia, United States • Chicago, Illinois, United States +7 more locations

COMPLETEDPhase 3< 1 mile

Advanced Chronic Myelogenous Leukemia (CML) - Follow On: Study of BMS-354825 in Subjects With CML

NCT00123487

This is a phase III study of BMS-354825 in subjects with chronic myelogenous leukemia in accelerated phase, or in myeloid or lymphoid blast phase or with Philadelphia chromosome positive (Ph+) acute lymphoblastic leukemia who are resistant or intolerant to imatinib mesylate (Gleevec).

Myeloid Leukemia, Chronic, Accelerated PhaseLeukemia, Lymphoblastic, Acute, Philadelphia-Positive

Bristol-Myers Squibb638 participantsStarted Jun 2005

Birmingham, Alabama, United States • Loma Linda, California, United States • Los Angeles, California, United States +116 more locations

Phase I/II Trial of Intracerebral IL13-PE38QQR Infusions in Pediatric Patients With Recurrent Malignant Glioma

Advanced Chronic Myelogenous Leukemia (CML) - Follow On: Study of BMS-354825 in Subjects With CML

Find Trials by Condition in Pittsburgh

Study to Assess the Clinical Efficacy and Safety of Intravitreal Aflibercept Injection (IAI;EYLEA®;BAY86-5321) in Patients With Branch Retinal Vein Occlusion (BRVO)

Safety and Efficacy of LX4211 With Metformin in Type 2 Diabetes Patients With Inadequate Glycemic Control on Metformin

Maraviroc in Rheumatoid Arthritis

Registry of AngioJet Use in the Peripheral Vascular System

Efficacy Study of REOLYSIN® in Combination With Paclitaxel and Carboplatin in Platinum-Refractory Head and Neck Cancers

Efficacy and Safety of Gadobutrol 1.0 Molar (Gadovist) for Breast Magnetic Resonance Imaging (MRI)

A Sleep Laboratory Study to Investigate the Safety and Efficacy of the Rotigotine Skin Patch in Subjects With Restless Legs Syndrome and End-Stage Renal Disease Requiring Hemodialysis

A Safety and Efficacy Study of Canagliflozin in Older Patients (55 to 80 Years of Age) With Type 2 Diabetes Mellitus

An Exploratory Genetic Study in Participants With Psoriasis

Efficacy of Electrical Stimulation for Dysphagia in Head & Neck Cancer Patients

Type 2 Diabetes Evaluation of Ranolazine in Subjects With Chronic Stable Angina

Evaluate the Efficacy and Safety of ABT-126 in Subjects With Mild to Moderate Alzheimer's Disease on Stable Doses of Acetylcholinesterase Inhibitors

Treatment Trial for Psychogenic Nonepileptic Seizures

Study of A Cell-Phone System to Improve Health of Youth With Diabetes

Responsive Feeding Study

Low-Dose or High-Dose Conditioning Followed by Peripheral Blood Stem Cell Transplant in Treating Patients With Myelodysplastic Syndrome or Acute Myelogenous Leukemia

An Exploratory Study of FP01 Lozenges in Subjects With Chronic Refractory Cough

ToGA Study - A Study of Herceptin (Trastuzumab) in Combination With Chemotherapy Compared With Chemotherapy Alone in Patients With HER2-Positive Advanced Gastric Cancer