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Clareo Health | Brain Cancer Clinical Trials in Pittsburgh | 83 Studies

Clinical Trials Brain CancerPittsburgh

Brain Cancer Clinical Trials in Pittsburgh

Find 83 clinical trials for brain cancer near Pittsburgh, Pennsylvania. Connect with research centers in your area.

All Brain Cancer trials nationwide All trials in Pittsburgh

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 1-20 of 83 trials

TerminatedTP-38 Toxin in Treating Young Patients With Recurrent or Progressive Supratentorial High-Grade GliomaRATIONALE: The TP-38 toxin can locate tumor cells and kill them without harming normal cells. Giving TP-38 toxin directly into the tumor may kill more tumor cells.NCT00074334·Washington D.C., District of Columbia and 7 others TerminatedGamma-Secretase/Notch Signalling Pathway Inhibitor RO4929097 in Treating Patients With Recurrent or Progressive GlioblastomaThis phase II trial is studying how well gamma-secretase/Notch signalling pathway inhibitor RO4929097 works in treating patients with recurrent or progressive glioblastoma.NCT01122901·Atlanta, Georgia and 4 others CompletedAdavosertib and Local Radiation Therapy in Treating Children With Newly Diagnosed Diffuse Intrinsic Pontine GliomasThis phase I trial studies the side effects and the best dose of adavosertib when given together with local radiation therapy in treating children with newly diagnosed diffuse…NCT01922076·Birmingham, Alabama and 23 others

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Data from ClinicalTrials.govTerms

CompletedRamucirumab or Anti-PDGFR Alpha Monoclonal Antibody IMC-3G3 in Treating Patients With Recurrent Glioblastoma MultiformeRATIONALE: Monoclonal antibodies, such as ramucirumab and anti-PDGFR alpha monoclonal antibody IMC-3G3 (Olaratumab), can block tumor growth in different ways.NCT00895180·Birmingham, Alabama and 10 others

Active not recruitingA Study Comparing Niraparib With Temozolomide in Adult Participants With Newly-diagnosed, MGMT Unmethylated GlioblastomaThe goal of this Phase 3 clinical trial is to compare the efficacy of niraparib versus temozolomide (TMZ) in adult participants with newly-diagnosed, MGMT unmethylated…NCT06388733·Birmingham, Alabama and 94 others

CompletedBusulfan in Treating Children and Adolescents With Refractory CNS CancerRATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.NCT00006246·San Francisco, California and 7 others

CompletedTipifarnib in Treating Patients With Recurrent or Progressive Malignant GliomaRATIONALE: Tipifarnib may stop the growth of tumor cells by blocking the enzymes necessary for tumor cell growth.NCT00005859·Los Angeles, California and 10 others

CompletedErlotinib in Treating Patients With Recurrent Malignant Glioma or Recurrent or Progressive MeningiomaPhase I/II trial to study the effectiveness of erlotinib in treating patients who have recurrent malignant glioma or recurrent or progressive meningioma.NCT00045110·Los Angeles, California and 6 others

CompletedErlotinib and Temsirolimus in Treating Patients With Recurrent Malignant GliomaErlotinib and temsirolimus and may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.NCT00112736·Los Angeles, California and 7 others

CompletedRadiation Therapy Plus Chemotherapy in Treating Patients With Supratentorial Glioblastoma MultiformeRATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. Chemotherapy uses different ways to stop tumor cells from dividing so they stop growing or die.NCT00002545·Birmingham, Alabama and 259 others

CompletedPhase I Study of APX005M in Pediatric Central Nervous System TumorsThis phase I trial studies the side effects and best dose of APX005M in treating younger patients with primary malignant central nervous system tumor that is growing, spreading…NCT03389802·Los Angeles, California and 10 others

CompletedZactima With Temodar During Radiation Treatment for Newly Diagnosed Stage IV Brain TumorsPhase I: The purpose of this research study is to determine the safety of the combination treatment of ZD6474 (Vandetanib) with the standard therapy for glioblastomas and…NCT00441142·Boston, Massachusetts and 6 others

CompletedChemotherapy Plus Peripheral Stem Cell Transplantation in Treating Infants With Malignant Brain or Spinal Cord TumorsRATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.NCT00003141·Duarte, California and 70 others

Completedp28 in Treating Younger Patients With Recurrent or Progressive Central Nervous System TumorsThis phase I trial studies the side effects and best dose of azurin-derived cell-penetrating peptide p28 (p28) in treating patients with recurrent or progressive central nervous…NCT01975116·Los Angeles, California and 10 others

CompletedRadiation Therapy and Tamoxifen in Treating Adults With Newly Diagnosed Supratentorial Glioblastoma MultiformeRATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. Drugs such as tamoxifen may make the tumor cells more sensitive to radiation therapy.NCT00006388·Birmingham, Alabama and 256 others

CompletedCapecitabine and Radiation Therapy in Treating Young Patients With Newly Diagnosed, Nonmetastatic Brain Stem Glioma or High-Grade GliomaRATIONALE: Drugs used in chemotherapy, such as capecitabine, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from…NCT00357253·San Francisco, California and 11 others

CompletedPazopanib in Treating Patients With Recurrent GlioblastomaThis phase II trial is studying the side effects and how well pazopanib works in treating patients with recurrent glioblastoma.NCT00459381·Los Angeles, California and 8 others

CompletedMibefradil Dihydrochloride and Temozolomide in Treating Patients With Recurrent GliomaRATIONALE: Mibefradil dihydrochloride may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.NCT01480050·Birmingham, Alabama and 6 others

CompletedSU-101 Compared With Procarbazine in Treating Patients With Glioblastoma MultiformeRATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.NCT00003293·Phoenix, Arizona and 34 others

CompletedRadiation Therapy Followed by Carmustine in Treating Patients Who Have Supratentorial Glioblastoma MultiformeRATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells.NCT00006386·Birmingham, Alabama and 235 others

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