Clinical Trials in Pittsburgh

Showing 6841-6860 of 16,007 trials

SBRT With Cetuximab +/- Docetaxel Followed by Adjuvant Cetuximab +/- Docetaxel in Recurrent, Previously-Irradiated SCCHN

NCT02057107

The aim of this trial is to examine the addition of docetaxel on disease progression, metastasis and survival of patients otherwise treated with SBRT and cetuximab alone. To better resolve the impact of the experimental treatment the presence/absence of prior cetuximab treatment will be determine before assigning treatment to either cetuximab and SBRT only or cetuximab, SBRT, and docetaxel.

Previously-IrradiatedSquamous Cell Carcinoma of the Head and Neck Cancer

Heath Skinner40 participantsStarted Jul 2013

Pittsburgh, Pennsylvania, United States

TERMINATEDPhase 1/2< 1 mile

Live Biotherapeutic Product MRx0518 and Pembrolizumab Combination Study in Solid Tumors

NCT03637803

This is an open label, safety and preliminary efficacy study of MRx0518 in combination with pembrolizumab in patients with solid tumours (non small cell lung cancer, renal cell carcinoma, bladder cancer or melanoma). Subjects will be treated with IV pembrolizumab every 3 weeks and 1 capsule twice daily of MRx0518. Treatment will continue as long as clinically relevant, until disease progression, unacceptable AEs or withdrawal of consent up to a maximum of 35 cycles (approx. 2 years).

OncologySolid TumorNon Small Cell Lung Cancer+3 more

4D pharma plc63 participantsStarted Jan 2019

Kansas City, Kansas, United States • Pittsburgh, Pennsylvania, United States • Houston, Texas, United States +2 more locations

SBRT With Cetuximab +/- Docetaxel Followed by Adjuvant Cetuximab +/- Docetaxel in Recurrent, Previously-Irradiated SCCHN

Live Biotherapeutic Product MRx0518 and Pembrolizumab Combination Study in Solid Tumors

Find Trials by Condition in Pittsburgh

Aromatherapy for Improving Post-Surgical Quality of Life

A Phase 1 Trial of CD33xCD3 BsAb in Pediatric Patients With Relapsed or Refractory Acute Myeloid Leukemia

Terbinafine HCl 250 mg Tablet Formulations Under Non-Fasting Conditions

Dimethyl Fumarate (DMF) Observational Study

Open-Label Study of Leuco-methylthioninium Bis(Hydromethanesulfonate) (LMTM) in Subjects With Alzheimer's Disease or Behavioral Variant Frontotemporal Dementia (bvFTD)

Single-Ascending Dose Study of JK07 in Subjects With HFpEF

A Study of Nivolumab or Nivolumab Plus Experimental Medication BMS-986205 With or Without Bacillus Calumette-Guerin (BCG) in BCG Unresponsive Bladder Cancer That Has Not Invaded Into the Muscle Wall of the Bladder

Comparing NUC-1031 Plus Cisplatin to Gemcitabine Plus Cisplatin in Patients With Advanced Biliary Tract Cancer

Rate of Atrial Fibrillation Through 12 Months in Patients With Recent Ischemic Stroke of Presumed Known Origin

Study of Diroximel Fumarate in the Real-World Setting

A Randomized, Controlled Trial of Ganaxolone in Patients With Infantile Spasms

Thrombosomes® in Bleeding Thrombocytopenic Patients Study

Convalescent Plasma to Limit SARS-CoV-2 Associated Complications

Aligning Medications With What Matters Most

An Study of Patidegib Topical Gel, 2%, for the Reduction of Disease Burden of Persistently Developing Basal Cell Carcinomas in Patients With Non-Gorlin High Frequency BCC

A Clinical Study of Efficacy, Safety, Tolerability and PK of ND0612H in Subjects With Advanced Parkinson's Disease

A Trial Comparing Nonacog Beta Pegol (N9-GP) and ALPROLIX® in Patients With Haemophilia B

A Study to Assess S-217622 in Participants With Mild and Moderate Hepatic Impairment and Healthy Control Participants