Clinical Trials in Pittsburgh

Showing 5401-5420 of 16,007 trials

Staying Active With Arthritis: RCT of Physical Activity for Older Adults With Osteoarthritis and Hypertension

NCT01280903

The purpose of the Staying Active with Arthritis (STAR) research study is to determine if a 6-month program will improve leg exercise, fitness walking, and clinical outcomes (function, blood pressure, leg strength, pain, fatigue, and health-related quality of life) in older adults with osteoarthritis of the knee and high blood pressure.

Osteoarthritis, KneeHypertension

University of Pittsburgh182 participantsStarted Jan 2012

Pittsburgh, Pennsylvania, United States

COMPLETED< 1 mile

Epigenetic Effects on Traumatic Brain Injury Recovery

NCT04186429

Methylation of the brain-derived neurotrophic factor (BDNF) gene is involved in both the biological encoding of childhood adversity and neuroplasticity following traumatic brain injury (TBI). This research will characterize BDNF methylation during recovery from TBI in children and investigate this novel biomarker as a potential biological mechanism underlying the known association between childhood adversity and poorer neurobehavioral outcomes following TBI in childhood. Findings from this research will contribute to an improved understanding of why some children display good recovery following TBI, whereas many others suffer from chronic neurobehavioral impairments.

Traumatic Brain InjuryOrthopedic Injury

University of Pittsburgh401 participantsStarted Jul 2017

Pittsburgh, Pennsylvania, United States

Staying Active With Arthritis: RCT of Physical Activity for Older Adults With Osteoarthritis and Hypertension

Epigenetic Effects on Traumatic Brain Injury Recovery

Find Trials by Condition in Pittsburgh

Clinical Evaluation of the i-STAT TBI Test

Study to Assess Efficacy and Safety of Cx601, Adult Allogeneic Expanded Adipose-derived Stem Cells (eASC) for the Treatment of Complex Perianal Fistula(s) in Participants With Crohn's Disease (CD)

Open-Label, Phase 1 Study to Evaluate Duration of Severe Neutropenia After Same-Day Dosing of Eflapegrastim in Patients With Breast-Cancer

IMP4297 in Combination With Temozolomide in Patients With Advanced Solid Tumors and Small Cell Lung Cancer

A Randomized Phase 2 Trial of TAS-114 in Combination With S-1 Versus S-1

Zephyrus I: Evaluation of Efficacy and Safety of Pamrevlumab in Participants With Idiopathic Pulmonary Fibrosis (IPF)

Strategies to Assist With Management of Pain

Phase IIa Study Evaluating Safety and Efficacy of BL-8040 in Relapsed/Refractory AML Patients

A Study to Evaluate Analgesic Efficacy and Safety of PRF-110 for Post-surgical Pain

First-in-Human Study of EOS100850 (Inupadenant) in Patients with Cancer

Phase 1, First-in-human Study of Oral TP-1287 in Patients with Advanced Solid Tumors

Pilot Trial of the RUBI Program for Autistic Adults

A Safety and Efficacy Study in Patients With Gastric Cancer

Peer Mentorship to Improve Outcomes in Patients on Maintenance Hemodialysis

A Trial to Assess Steviol Glycosides on Acute Appetite Hormone Release

Clinical Trial Comparing C-Brace to Knee Ankle Foot Orthosis (KAFO)/Stance Control Orthosis (SCO)

Encore PFO Closure Device - The PerFOrm Trial

Target Controlled Infusion Using Propofol and Remifentanil for Moderate Sedation in Dentistry